Profile

Tan ZhangWake Forest School of Medicine

Tan Zhang

Assistant Professor,

Contact Information

Academic: 336-716-9820 | Department: 336-716-6918

Education & Training

  • M.D., Qingdao Medical College-China, 1998
  • Ph.D., Peking University, 2004
  • Fellowship, Musculoskeletal, National Institues of Health, 2009
  • Fellowship, Geriatric Medicine, WFU School of Medicine, 2013

Memberships

  • Biophysics Society
Tan Zhang

Tan Zhang

Assistant Professor, Gerontology and Geriatric Medicine

Research Interests

Troponin T; Muscle, Skeletal; Aging; Cell Nucleus; Pericytes
More »

Contact Information

Academic: 336-716-9820 | Department: 336-716-6918

Recent Publications

Intramyocellular lipid and impaired myofiber contraction in normal weight and obese older adults. Choi SJ, Files DC, Zhang T, Wang ZM, Messi ML, Gregory H, Stone J, Lyles MF, Dhar S, Marsh AP, Nicklas BJ, Delbono O.. J Gerontol A Biol Sci Med Sci. 2016;71(4):557-564.

Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice. Zhang T, Pereyra AS, Wang ZM, Birbrair A, Reisz JA, Files DC, Purcell L, Feng X, Messi ML, Feng H, Chalovich J, Jin JP, Furdui C, Delbono O.. Aging Cell. 2016;15(3):488-498.

Pericytes at the intersection between tissue regeneration and pathology. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Clin Sci (Lond). 2015;128(2):81-93.

Improved knee extensor strength with resistance training associates with muscle specific miRNAs in older adults. Zhang T, Birbrair A, Wang ZM, Messi ML, Marsh AP, Leng I, Nicklas BJ, Delbono O.. Exp Gerontol. 2015;62():7-13.

Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting. Files DC, Liu C, Pereyra A, Wang ZM, Aggarwal NR, D'Alessio FR, Garibaldi BT, Mock JR, Singer BD, Feng X, Yammani RR, Zhang T, Lee AL, Philpott S, Lussier S, Purcell L, Chou J, Seeds M, King LS, Morris PE, Delbono O.. Sci Transl Med. 2015;7(278):278ra32.

Troponin T3 regulates nuclear localization of the calcium channel Cavbeta1a subunit in skeletal muscle. Zhang T, Taylor J, Jiang Y, Pereyra AS, Messi ML, Wang ZM, Herenu C, Delbono O.. Exp Cell Res. 2015;336(2):276-286.

Traditional Chinese medicine and vascular disease [editorial]. Xing Y, Hu D, Zhang T, Antzelevitch C.. Evid Based Complement Alternat Med. 2015;2015():430818.

MiRNAs as biomarkers of the gait speed response to aerobic exercise training in obese older adults [abstract]. Zhang T, Liu KQ, Brinkley TE, Feng X, Marsh A, Nicklas B, Zhou XB, Kritchevsky SB.. Gerontologist. 2015;55(Suppl 2):338.

The posterior cricoarytenoid muscle is spared from MuRF1-mediated muscle atrophy in mice with acute lung injury. Files DC, Xiao K, Zhang T, Liu C, Qian J, Zhao W, Morris PE, Delbono O, Feng X.. PLoS One. 2014;9(1):e87587.

Human slow troponin T (TNNT1) Pre-mRNA alternative splicing is an indicator of skeletal muscle response to resistance exercise in older adults. Zhang T, Choi SJ, Wang ZM, Birbrair A, Messi ML, Jin JP, Marsh AP, Nicklas B, Delbono O.. J Gerontol A Biol Sci Med Sci. 2014;69(12):1437-1447.

Type-2 pericytes participate in normal and tumoral angiogenesis. Birbrair A, Zhang T, Wang ZM, Messi ML, Olson JD, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2014;307(1):C25-C38.

The CaVbeta1A subunit regulates gene expression and suppresses myogenin in muscle progenitor cells. Taylor J, Pereyra A, Zhang T, Messi ML, Wang ZM, Herenu C, Kuan PF, Delbono O.. J Cell Biol. 2014;205(6):829-846.

Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Front Aging Neurosci. 2014;6():245.

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner. Birbrair A, Zhang T, Files DC, Mannava S, Smith T, Wang ZM, Messi ML, Mintz A, Delbono O.. Stem Cell Res Ther. 2014;5(6):122.

Skeletal muscle neural progenitor cells exhibit properties of NG2-glia. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Exp Cell Res. 2013;319(1):45-63.

Skeletal muscle pericyte subtypes differ in their differentiation potential. Birbrair A, Zhang T, Wang Z-M, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cell Res. 2013;10(1):67-84.

Troponin T nuclear localization and its role in aging skeletal muscle. Zhang T, Birbrair A, Wang ZM, Taylor J, Messi ML, Delbono O.. Age (Dordr). 2013;35(2):353-370.

Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis. Zhang T, Birbrair A, Delbono O.. Cytoskeleton (Hoboken). 2013;70(3):134-147.

Role of pericytes in skeletal muscle regeneration and fat accumulation. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cells Dev. 2013;22(16):2298-2314.

Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2013;305(11):C1098-1113.

Myosin heavy chain isoform expression in the Vastus Lateralis muscle of aging African green vervet monkeys. Feng X, Zhang T, Xu Z, Choi SJ, Qian J, Furdui CM, Register TC, Delbono O.. Exp Gerontol. 2012;47(8):601-607.

Effects of aging and levodopa on the laryngeal adductor reflex in rats. Feng X, Xu Z, Butler SG, Leng I, Zhang T, Kritchevsky SB.. Exp Gerontol. 2012;47(12):900-907.

Non-classical role of troponin T in skeletal muscle [abstract]. Zhang T, Birbrair A, Wang Z, Taylor J, Messi ML, Delbono O.. Gerontologist. 2012;52(Suppl 1):289.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Gerontology and Geriatric Medicine

Tan Zhang

Tan Zhang

Assistant Professor, Gerontology and Geriatric Medicine

Quick Reference

Request an Appointment
New Patients

336-716-WAKE
888-716-WAKE

Existing patients may contact the clinic directly.
Find a Doctor Ways to Give
Magnet Hospital RecognitionConsumer Choice2015 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.