Profile

Zhu-Ming Zhang, M.D., M.P.H.Wake Forest School of Medicine

Zhu-Ming Zhang, M.D., M.P.H.

Associate Professor,

Clinical Interests

Arrhythmias, Atherosclerosis, Clinical Trials, Coronary Artery Disease, Electrocardiography

Contact Information

Academic: 336-716-0835 | Department: 336-716-2011

Email: zmzhang@wakehealth.edu

Education & Training

  • M.P.H., Beijing Capital Institute In Med-China, 1986
  • M.D., Shandong Medical University-China, 2013
Zhu-Ming Zhang, M.D., M.P.H.

Zhu-Ming Zhang, M.D., M.P.H.

Associate Professor, Epidemiology & Prevention

Research Interests

diabetes, environmental sciences, genetics/genome

Contact Information

Academic: 336-716-0835 | Department: 336-716-2011

Email: zmzhang@wakehealth.edu

Recent Publications

McClure LA, Zheng DD, Lam BL, Tannenbaum SL, Joslin CE, Davis S, Lopez-Cevallos D, Youngblood ME Jr, Zhang ZM, Chambers CP, Lee DJ. Factors associated with ocular health care utilization among Hispanics/Latinos: results from an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). JAMA Ophthalmol. 2016;134(3):320-329.

O'Neal WT, Qureshi W, Zhang ZM, Soliman EZ. Bidirectional association between atrial fibrillation and congestive heart failure in the elderly. J Cardiovasc Med (Hagerstown). 2016;17(3):181-186.

Soliman EZ, Backlund JY, Bebu I, Li Y, Zhang ZM, Cleary PA, Lachin JM. Progression of electrocardiographic abnormalities in type 1 diabetes during 16 years of follow-up: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. J Am Heart Assoc. 2016;5(3):e002882.

O'Neal WT, Zhang ZM, Loehr LR, Chen LY, Alonso A, Soliman EZ. Electrocardiographic advanced interatrial block and atrial fibrillation risk in the general population. Am J Cardiol. 2016;():.

Rautaharju PM, Zhang ZM, Haisty WK Jr, Kucharska-Newton AM, Rosamond WD, Soliman EZ. Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study. J Electrocardiol. 2015;48(1):101-111.

Zhang ZM, Rautaharju PM, Prineas RJ, Loehr L, Rosamond W, Soliman EZ. Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study. J Cardiovasc Med (Hagerstown). 2015;():.

Zhang ZM, Rautaharju PM, Prineas RJ, Loehr L, Rosamond W, Soliman EZ. Ventricular conduction defects and the risk of incident heart failure in the Atherosclerosis Risk in Communities (ARIC) study. J Card Fail. 2015;21(4):307-312.

Soliman EZ, Lopez F, O'Neal WT, Chen LY, Bengtson L, Zhang ZM, Loehr L, Cushman M, Alonso A. Atrial fibrillation and risk of ST-segment-elevation versus non-ST-segment-elevation myocardial infarction: the Atherosclerosis Risk in Communities (ARIC) study. Circulation. 2015;131(21):1843-1850.

Zhang ZM, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko L, Soliman EZ. A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study. J Electrocardiol. 2015;48(4):672-677.

Estes EH, Zhang ZM, Li Y, Tereschenko LG, Soliman EZ. The Romhilt-Estes left ventricular hypertrophy score and its components predict all-cause mortality in the general population. Am Heart J. 2015;170(1):104-109.

Estes EH, Zhang ZM, Li Y, Tereshchenko LG, Soliman EZ. Individual components of the Romhilt-Estes left ventricular hypertrophy score differ in their prediction of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J. 2015;170(6):1220-1226.

Dawood FZ, Roediger MP, Grandits G, Miller D, Fisher M, Zhang ZM, Hodder S, Hoy JF, Lundgren JD, Neaton JD, Soliman EZ. Determinants of developing widened spatial QRS-T angle in HIV-infected individuals: results from the Strategies for Management of Antiretroviral Therapy [SMART] Study. J Electrocardiol. 2014;47(2):264-271.

Rautaharju PM, Zhang ZM, Haisty WK Jr, Gregg RE, Warren J, Horacek MB, Kucharska-Newton AM, Rosamond W, Soliman EZ. Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study. J Electrocardiol. 2014;47(3):342-350.

Zhang ZM, Rautaharju PM, Prineas RJ, Loehr L, Rosamond W, Soliman EZ. Usefulness of electrocardiographic QRS/T angles with versus without bundle branch blocks to predict heart failure (from the Atherosclerosis Risk in Communities Study). Am J Cardiol. 2014;114(3):412-418.

Rautaharju PM, Zhang ZM, Vitolins M, Perez M, Allison MA, Greenland P, Soliman EZ. Electrocardiographic repolarization-related variables as predictors of coronary heart disease death in the Women's Health Initiative study. J Am Heart Assoc. 2014;3(4):e001005.

O'Neal WT, Sangal K, Zhang ZM, Soliman EZ. Atrial fibrillation and incident myocardial infarction in the elderly. Clin Cardiol. 2014;37(12):750-755.

Dawood FZ, Khan F, Roediger MP, Zhang ZM, Swaminathan S, Klinker H, Hoy J, Lundgren JD, Neaton JD, Soliman EZ. Electrocardiographic spatial QRS-T angle and incident cardiovascular disease in HIV-infected patients (from the Strategies for the Management of Antiretroviral Therapy [SMART] study). Am J Cardiol. 2013;111(1):118-124.

Zhang ZM, Rautaharju PM, Soliman EZ, Manson JE, Martin LW, Perez M, Vitolins M, Prineas RJ. Different patterns of bundle-branch blocks and the risk of incident heart failure in the Women's Health Initiative (WHI) study. Circ Heart Fail. 2013;6(4):655-661.

Rautaharju PM, Zhang ZM, Haisty WK Jr, Prineas RJ, Kucharska-Newton AM, Rosamond WD, Soliman EZ. Electrocardiographic predictors of incident heart failure in men and women free from manifest cardiovascular disease (from the Atherosclerosis Risk in Communities [ARIC] study. Am J Cardiol. 2013;112(6):843-849.

Rautaharju PM, Zhang ZM, Warren J, Gregg RE, Haisty WK, Kucharska-Newton AM, Rosamond WD, Soliman EZ. Electrocardiographic predictors of coronary heart disease and sudden cardiac deaths in men and women free from cardiovascular disease in the Atherosclerosis Risk in Communities study. J Am Heart Assoc. 2013;2(3):e000061.

Denes P, Garside DB, Lloyd-Jones D, Gouskova N, Soliman EZ, Ostfeld R, Zhang ZM, Camacho A, Prineas R, Raij L, Daviglus ML. Major and minor electrocardiographic abnormalities and their association with underlying cardiovascular disease and risk factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos). Am J Cardiol. 2013;112(10):1667-1675.

Rautaharju PM, Zhang ZM, Gregg RE, Haisty WK Jr, Z Vitolins M, Curtis AB, Warren J, Horacek MB, Zhou SH, Soliman EZ. Normal standards for computer-ECG programs for prognostically and diagnostically important ECG variables derived from a large ethnically diverse female cohort: the Women's Health Initiative (WHI). J Electrocardiol. 2013;46(6):707-716.

Gupta DK, Shah AM, Rautaharju PM, Heiss G, Fox E, Mnsley T, Zhang ZM, Prineas RJ, Loehr L, Rosamond W, Soliman EZ, Solomon SD. The relationships between QRS duration and morphology, cardiac structure and function, and incident heart failure in the Atherosclerosis Risk In Communities Study [abstract]. Circulation. 2013;128(22 Suppl):A17411.

Prineas RJ, Le A, Soliman EZ, Zhang Z-M, Howard VJ, Ostchega Y, Howard G. United States national prevalence of electrocardiographic abnormalities in black and white middle-age (45- to 64-Year) and older (greater than or equal to 65-Year) adults (from the Reasons for Geographic and Racial Differences in Stroke Study). Am J Cardiol. 2012;109(8):1223-1228.

Stiles MC, Seaquist ER, Yale JF, Green JB, Katz LA, Kempainen S, Light LS, Pepper PV, Zhang ZM, Soliman EZ. Is silent myocardial infarction more common in women with type 2 diabetes than in men?. J Diabetes Complications. 2012;26(2):118-122.

Zhang ZM, Prineas RJ, Soliman EZ, Baggett C, Heiss G. Prognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2012;19(6):1430-1436.

Zhang ZM, Rautaharju PM, Soliman EZ, Manson JE, Cain ME, Martin LW, Bavry AA, Mehta L, Vitolins M, Prineas RJ. Mortality risk associated with bundle branch blocks and related repolarization abnormalities (from the Women's Health Initiative [WHI]). Am J Cardiol. 2012;110(10):1489-1495.

Butler AM, Yin X, Evans DS, Nalls MA, Smith EN, Tanaka T, Li G, Buxbaum SG, Whitsel EA, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen W, Deo R, Ellinor PT, Heckbert SR, Heiss G, Hsueh WC, Keating BJ, Kerr KF, Li Y,. Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. Circ Cardiovasc Genet. 2012;5(6):639-646.

Smith JG, Avery CL, Evans DS, Nalls MA, Meng YA, Smith EN, Palmer C, Tanaka T, Mehra R, Butler AM, Young T, Buxbaum SG, Kerr KF, Berenson GS, Schnabel RB, Li G, Ellinor PT, Magnani JW, Chen W, Bis JC, Curb JD, Hsueh WC,. Impact of ancestry and common genetic variants on QT interval in African Americans. Circ Cardiovasc Genet. 2012;5(6):647-655.

Zhang Z-m, Prineas RJ, Case D, Psaty BM, Suzuki T, Burke GL. Gender differences between the Minnesota code and Novacode electrocardiographic prognostication of coronary heart disease in the Cardiovascular Health Study. Am J Cardiol. 2011;107(6):817-820.

Gorodeski EZ, Ishwaran H, Kogalur UB, Blackstone EH, Hsich E, Zhang Z-m, Vitolins MZ, Manson JE, Curb JD, Prineas RJ, et al. Use of hundreds of electrocardiographic biomarkers for prediction of mortality in postmenopausal women: the Women's Health Initiative. Circ Cardiovasc Qual Outcomes. 2011;4(5):521-532.

Prineas RJ, Crow RS, Zhang Z-M. In: The Minnesota code manual of electrocardiographic findings including measurement and comparison with the Novacode; standards and procedures for ECG measurement in epidemiologic and clinical trials. 2nd ed [Internet]. London: Springer;2010: .

Zhang Z-m, Prineas RJ, Eaton CB. Evaluation and comparison of the Minnesota Code and Novacode for electrocardiographic Q-ST wave abnormalities for the independent prediction of incident coronary heart disease and total mortality (from the Women's Health Initiative). Am J Cardiol. 2010;106(1):18-25.

Liao DP, Whitsel E, Duan YK, Lin HM, Quibrera PM, Smith R, Peuquet D, Prineas R, Zhang ZM, Anderson G. Ambient particulate air pollution and ectopy the environmental epidemiology of arrhythmogenesis in Women's Health Initiative Study, 1999-2004. J Toxicol Environ Health A. 2009;72(1):30-38.

Soliman EZ, Prineas RJ, Case LD, Zhang Z-m, Goff DC Jr. Ethnic distribution of ECG predictors of atrial fibrillation and its impact on understanding the ethnic distribution of ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) Study. Stroke. 2009;40(4):1204-1211.

Zhang Z-m, Whitsel EA, Quibrera PM, Smith RL, Liao D, Anderson GL, Prineas RJ. Ambient fine particulate matter exposure and myocardial ischemia in the Environmental Epidemiology of Arrhythmogenesis in the Women's Health Initiative (EEAWHI) study. Environ Health Perspect. 2009;117(5):751-756.

Liao Y-T, Li W-F, Chen C-J, Prineas RJ, Chen WJ, Zhang Z-M, Sun C-W, Wang S-L. Synergistic effect of polymorphisms of paraoxonase gene cluster and arsenic exposure on electrocardiogram abnormality. Toxicol Appl Pharmacol. 2009;239(2):178-183.

Prineas RJ, Soliman EZ, Howard G, Howard VJ, Cushman M, Zhang Z-M, Moy CS. The sensitivity of the method used to detect atrial fibrillation in population studies affects group-specific prevalence estimates: ethnic and regional distribution of atrial fibrillation in the REGARDS study. J Epidemiol. 2009;19(4):177-181.

Whitsel EA, Quibrera PM, Prineas RJ, Zhang Z-m, Liao D, Peuquet DJ, Anderson GL, Catellier DJ, Chen J-C, Smith RL. Ventricular repolarization, systolic hypertension, and ambient particulate air pollution: the Environmental Epidemiology of Arrhythmogenesis in WHI (EEAWHI), 1999-2002 [abstract]. Circulation. 2007;115(8):e256.

Rautaharju PM, Prineas RJ, Zhang Z-M. A simple procedure for estimation of the spatial QRS/T angle from the standard 12-lead electrocardiogram. J Electrocardiol. 2007;40(3):300-304.

Zhang Z-m, Prineas RJ, Case D, Soliman EZ, Rautaharju PM. Comparison of the prognostic significance of the electrocardiographic QRS/T angles in predicting incident coronary heart disease and total mortality (from the Atherosclerosis Risk In Communities Study). Am J Cardiol. 2007;100(5):844-849.

Rautaharju PM, Prineas RJ, Wood J, Zhang Z-M, Crow R, Heiss G. Electrocardiographic predictors of new-onset heart failure in men and in women free of coronary heart disease (from the Atherosclerosis in Communities [ARIC] Study). Am J Cardiol. 2007;100(9):1437-1441.

Liao D, Whitsel EA, Duan Y, Lin H-M, Quibrera M, Smith RL, Peuquet DJ, Prineas RJ, Zhang Z-M, Anderson G. Ambient particulate air pollution and ectopy--the Environmental Epidemiology of Arrhythmogenesis in WHI (EEAWHI), 1999-2004 [abstract]. Circulation. 2007;116(16 Suppl):785.

Prineas R, McClure L, Zhang ZM, Howard GH, Cushman M. Left ventricular hypertrophy in the stroke belt, contrasted with the rest of the USA: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study [abstract]. Circulation. 2006;114(18 Suppl):629.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Epidemiology & Prevention

Clinical Interests

Arrhythmias, Atherosclerosis, Clinical Trials, Coronary Artery Disease, Electrocardiography
Zhu-Ming Zhang, M.D., M.P.H.

Zhu-Ming Zhang, M.D., M.P.H.

Associate Professor, Epidemiology & Prevention

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