BUN - Blood Test


Definition

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down.

A test can be done to measure the amount of urea nitrogen in the blood.


Alternative Names

Blood urea nitrogen


How the test is performed

A blood sample is needed. For information on how this is done, see: Venipuncture


How to prepare for the test

Many drugs affect BUN levels. Before having this test, make sure the health care provider knows which medications you are taking.

Drugs that can increase BUN measurements include:

  • Allopurinol
  • Aminoglycoside antibiotics
  • Amphotericin B
  • Aspirin (high doses)
  • Bacitracin
  • Carbamazepine
  • Cephalosporins
  • Chloral hydrate
  • Cisplatin
  • Colistin
  • Furosemide
  • Guanethidine
  • Indomethacin
  • Methicillin
  • Methotrexate
  • Methyldopa
  • Neomycin
  • Penicillamine
  • Polymyxin B
  • Probenecid
  • Propranolol
  • Rifampin
  • Spironolactone
  • Tetracyclines
  • Thiazide diuretics
  • Triamterene
  • Vancomycin

Drugs that can decrease BUN measurements include:

  • Chloramphenicol
  • Streptomycin

How the test will feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.


Why the test is performed

The BUN test is often done to check kidney function.


References

Clarkson MR, Friedewald JJ, Eustace JA, Rabb H. Acute kidney injury. In: Brenner BM, eds. Brenner and Rector’s The Kidney. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 29.


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Review Date: 5/30/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 8/30/2011
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