Calcium - Blood Test


Definition

All cells need calcium in order to work. Calcium helps build strong bones and teeth. It is important for heart function, and helps with muscle contraction, nerve signaling, and blood clotting.

This article discusses the test to measure the total amount of calcium in your blood.

Calcium can also be measured in the urine. See: Calcium - urine test


Alternative Names

Ca+2; Serum calcium; Ca++


How the test is performed

A blood sample is needed. For information on how this is done, see: Venipuncture


How to prepare for the test

Your health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test.

Drugs that can increase calcium levels include:

  • Calcium salts (may be found in nutritional supplements or antacids)
  • Lithium
  • Thiazide diuretics
  • Thyroxine
  • Vitamin D

Drinking too much milk (two or more quarts a day) or taking too much vitamin D as a dietary supplement can also increase blood calcium levels.


How the test will feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.


Why the test is performed

Your doctor may order this test if you have signs or symptoms of:

  • Certain bone diseases
  • Certain cancers, such as multiple myeloma, a cancer of the breast, lung, neck, and kidney, especially during cancer treatment
  • Disorders of the parathyroid gland
  • Disorders that affect how your intestines absorb nutrients
  • Overactive thyroid gland or taking too much thyroid hormone medication

Your doctor may also order this test if you have been on bed rest for a long time.

About half of the calcium in the blood is attached to proteins. A separate test measures calcium that is not attached to proteins in your blood. Such calcium is called free or ionized calcium. See: Calcium - ionized


References

Wysolmerski JJ, Insogna KL. The parathyroid glands, hypercalcemia, and hypocalcemia. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 253.


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Review Date: 11/17/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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