Culture - colonic tissue


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Definition

A colonic tissue culture is a laboratory test to check for disease-causing bacteria, fungi, or viruses in a sample of tissue from the large intestine.


Alternative Names

Colonic tissue culture


How the test is performed

The doctor removes a piece of tissue from your large intestine during a colonoscopy. For more information on how this procedure is done, see colonoscopy.

The sample is sent to a laboratory where it is placed in a special dish containing a gel on which microoganisms can grow, and stored at a certain temperature. The laboratory team checks the sample daily to see if bacteria, viruses, or fungi have grown.

If certain microorganisms grow, more tests will be done to further identify them. This helps determine the best treatment.


How to prepare for the test

There is no specific preparation needed for a culture. For information on how to prepare for the procedure to remove a piece of tissue from your large intestine, see colonoscopy.


How the test will feel

The laboratory culture does not involve the patient, so there is no pain.

For information on how it will feel to have a piece of large intestine tissue removed, see colonoscopy.


Why the test is performed

Your doctor may order this test if you have signs or symptoms of an infection that can affect the large intestine. A culture is often done when other tests such as a stool culture could not identify the cause of infection.


References

Semrad CE, Powell DW. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 143.

Steiner TS, Guerrant RL. Principles and syndromes of enteric infection. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 93.


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Review Date: 5/4/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 5/13/2011
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