Gastritis


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Definition

Gastritis occurs when the lining of the stomach becomes inflamed or swollen.

Gastritis can last for only a short time (acute gastritis), or linger for months to years (chronic gastritis).


Causes, incidence, and risk factors

The most common causes of gastritis are:

  • Certain medications, such as aspirin, ibuprofen, or naproxen, when taken over a longer period of time
  • Drinking too much alcohol
  • Infection of the stomach with a bacteria called Helicobacter pylori

Less common causes are:

  • Backflow of bile into the stomach (bile reflux)
  • Cocaine abuse
  • Eating or drinking caustic or corrosive substances (such as poisons)
  • Extreme stress
  • Viral infection, such as cytomegalovirus and herpes simplex virus, especially in people with a weak immune system

Trauma or a severe, sudden illness such as major surgery, kidney failure, or being placed on a breathing machine may cause gastritis.


References

Kuipers, E. Acid peptic disease. In: Goldman L, Ausiello D. Cecil Textbook of Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 141.

Lee EL, Feldman M. Gastritis and gastropathies. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier;2010:chap 51.


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Review Date: 1/31/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 5/16/2011
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