Horner syndrome


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Definition

Horner syndrome is a rare condition that affects the nerves to the eye and face.


Causes, incidence, and risk factors

Horner syndrome can be caused by any interruption in a set of nerve fibers that start in the part of the brain called the hypothalamus and run to the face.

Sympathetic nerve fiber injuries can result from:

  • Injury to one of the main arteries to the brain (carotid artery)
  • Injury to nerves in the neck called the brachial plexus
  • Migraine or cluster headaches
  • Stroke, tumor, or other damage to a part of the brain called the brainstem
  • Tumor in the top of the lung

Rarely, Horner syndrome may be present at birth (congenital). The condition may occur with a lack of color (pigmentation) of the iris (colored part of the eye).


References

Baloh RW. Neuro-ophthalmology. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 450.

Saper CB. Autonomic disorders and their management. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 445.


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Review Date: 6/15/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 5/13/2011
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