Miscarriage


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Definition

A miscarriage is the spontaneous loss of a fetus before the 20th week of pregnancy. (Pregnancy losses after the 20th week are called preterm deliveries.)

A miscarriage may also be called a "spontaneous abortion." This refers to naturally occurring events, not medical abortions or surgical abortions.

Other terms for the early loss of pregnancy include:

  • Complete abortion: All of the products of conception exit the body
  • Incomplete abortion: Only some of the products of conception exit the body
  • Inevitable abortion: The symptoms cannot be stopped, and a miscarriage will happen
  • Infected (septic) abortion: The lining of the womb, or uterus, and any remaining products of conception become infected
  • Missed abortion: The pregnancy is lost and the products of conception do not exit the body

See also: Threatened miscarriage


Alternative Names

Abortion - spontaneous; Spontaneous abortion; Abortion - missed; Abortion - incomplete; Abortion - complete; Abortion - inevitable; Abortion - infected; Missed abortion; Incomplete abortion; Complete abortion; Inevitable abortion; Infected abortion


Causes, incidence, and risk factors

Most miscarriages are caused by chromosome problems that make it impossible for the baby to develop. Usually, these problems are unrelated to the mother or father's genes.

Other possible causes for miscarriage include:

  • Drug and alcohol abuse
  • Exposure to environmental toxins
  • Hormone problems
  • Infection
  • Obesity
  • Physical problems with the mother's reproductive organs
  • Problem with the body's immune response
  • Serious body-wide ( systemic) diseases in the mother (such as uncontrolled diabetes)
  • Smoking

It is estimated that up to half of all fertilized eggs die and are lost (aborted) spontaneously, usually before the woman knows she is pregnant. Among those women who know they are pregnant, the miscarriage rate is about 15-20%. Most miscarriages occur during the first 7 weeks of pregnancy. The rate of miscarriage drops after the baby's heart beat is detected.

The risk for miscarriage is higher in women:

  • Older age, with increases beginning by 30, becoming greater between 35 and 40, and highest after 40
  • Who have had previous miscarriages

References

Katz VL. Spontaneous and recurrent abortion: etiology, diagnosis, treatment. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 16.

Simpson JL, Jauniaux ERM. Pregnancy loss. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2007:chap 24.

Laurino MY, Bennett RL, Saraiya DS, et al. Genetic evaluation and counseling of couples with recurrent miscarriage: Recommendations of the National Society of Genetic Counselors. J Genet Couns. June 2005;14(3).


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Review Date: 11/21/2010
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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