Myocarditis


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Definition

Myocarditis is inflammation of the heart muscle.

See also: Pediatric myocarditis


Alternative Names

Inflammation - heart muscle


Causes, incidence, and risk factors

Myocarditis is an uncommon disorder that is usually caused by viral, bacterial, or fungal infections that reach the heart.

Viral infections:

Bacterial infections:

Fungal infections:

  • Aspergillus
  • Candida
  • Coccidioides
  • Cryptococcus
  • Histoplasma

When you have an infection, your immune system produces special cells that release chemicals to fight off disease. If the infection affects your heart, the disease-fighting cells enter the heart. However, the chemicals produced by an immune response can damage the heart muscle. As a result, the heart can become thick, swollen, and weak. This leads to symptoms of heart failure.

Other causes of myocarditis may include:

  • Allergic reactions to certain medications or toxins (alcohol, cocaine, certain chemotherapy drugs, heavy metals, and catecholamines)
  • Being around certain chemicals
  • Certain diseases that cause inflammation throughout the body (rheumatoid arthritis, sarcoidosis)

References

Liu PP, Schultheiss HP. Myocarditis. In: Libby P, Bonow RO, Mann DL, Zipes DP. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 66.


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Review Date: 5/4/2010
Reviewed By: A.D.A.M. Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Issam Mikati, MD, Associate Professor of Medicine. Feinberg School of Medicine, Northwestern University, Chicago, IL. Review provided by VeriMed Healthcare Network (5/4/2010).
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Last Updated 5/16/2011
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