Health Encyclopedia

Typical Smallpox Vaccine Reaction

Typical Smallpox Vaccine Reaction

Typical skin reaction at the site of a smallpox vaccine injection

Source: U.S. Centers for Disease Control and Prevention (CDC). Available online: http://www.bt.cdc.gov

The pictures show a typical reaction to the smallpox vaccine. First, a small bump (papule) forms at the vaccine site 3 to 5 days after vaccination. This becomes a pus-filled area (pustule) a few days later. The pustule dries up and then forms a scab by about 14 days after vaccination. The scab finally falls off at about 21 days after vaccination.

By Healthwise Staff
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer Christine Hahn, MD - Epidemiology
Last Revised December 27, 2012

Last Revised: December 27, 2012

Author: Healthwise Staff

Medical Review: E. Gregory Thompson, MD - Internal Medicine & Christine Hahn, MD - Epidemiology

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

To learn more visit Healthwise.org

© 1995-2013 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

USNWR 2012-2013Best Doctors 2011-2012 AwardMagnet Hospital RecognitionIndependent Measures of Excellence298 Wake Forest Baptist Physicians Named to Prestigious 2013 Best Doctors

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.