About 1 out of 3 people with
lupus produce an
antibody that attacks certain blood-clotting factors,
which can cause the blood to clot easily.1 A person who has this antibody and has had blood clots is said to have antiphospholipid antibody syndrome. This
can lead to mild or severe blood-clotting complications, including:
A blood test can detect antiphospholipid antibodies. When diagnosed, the condition is usually treated with
anticoagulants. Pregnant women with antiphospholipid
antibody syndrome need to be closely monitored.
Crow MK (2012). Systemic lupus erythematosus. In L Goldman, A Schafer, eds., Goldman's Cecil Medicine, 24th ed., pp. 1697–1705. Philadelphia: Saunders.
May 10, 2012
Anne C. Poinier, MD - Internal Medicine
& Nancy Ann Shadick, MD, MPH - Internal Medicine, Rheumatology
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