Phosphodiesterase-5 inhibitors, such as sildenafil
(for example, Viagra), have revolutionized the
erection problems (erectile dysfunction). But they can
cause life-threatening side effects for anyone who also takes nitroglycerin or
another medicine containing an organic nitrate. This combination can make your
blood pressure fall too low, possibly leading to a
heart attack, or death. Do not take nitrate-containing
medicines up to 24 hours after you take sildenafil (for example, Viagra) or vardenafil
(for example, Levitra), or up to 48 hours after you take tadalafil (for example, Cialis).
Medicines that contain organic nitrates include:
Nitrates found in foods are not a danger when taking
Other Works Consulted
Levine GN, et al. (2012). Sexual activity and cardiovascular disease: A scientific statement from the American Heart Association. Circulation, 125(8): 1058–1072.
May 14, 2012
E. Gregory Thompson, MD - Internal Medicine
& Christopher G. Wood, MD, FACS - Urology, Oncology
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