Health Encyclopedia > Medications

levorphanol

Pronunciation: lee VOR fa nole

Brand: Levo-Dromoran

Levorphanol 2 mg-ROX

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Image of Levorphanol 2 mg-ROX
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What is the most important information I should know about levorphanol?

Multum donot

You should not use levorphanol if you are allergic to it.

Multum donot

Do not use levorphanol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Multum habit

Levorphanol may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Multum noalcohol

Do not drink alcohol while you are using this medication. Dangerous side effects or death can occur when alcohol is combined with levorphanol. Check your food and medicine labels to be sure these products do not contain alcohol.

Never take levorphanol in larger amounts, or for longer than recommended by your doctor. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Multum dizzy

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how levorphanol will affect you.

What is levorphanol?

Levorphanol is an opioid pain medication. An opioid is sometimes called a narcotic.

Levorphanol is used to treat moderate to severe pain.

Levorphanol may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking levorphanol?

Multum donot

You should not use levorphanol if you are allergic to it.

Multum donot

Do not use levorphanol if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

You should not use levorphanol unless you are already being treated with a similar opioid medicine and your body is tolerant to it. Opioid medicines include fentanyl (Actiq, Duragesic), hydromorphone (Dilaudid, Palladone), methadone (Methadose, Dolophine), morphine (Kadian, MS Contin, Oramorph), oxycodone (Oxycontin), oxymorphone (Opana), and many others. Talk with your doctor if you are not sure you are opioid-tolerant.

To make sure you can safely take levorphanol, tell your doctor if you have any of these other conditions:

  • asthma, COPD, sleep apnea, or other breathing disorder;
  • liver or kidney disease;
  • heart disease;
  • low blood pressure;
  • a history of head injury or brain tumor;
  • a thyroid disorder;
  • gallbladder disease;
  • enlarged prostate or urination problems;
  • an adrenal gland tumor or disorder (such as Addison's disease);
  • mental illness;
  • a history of alcoholism or drug addiction; or
  • if you recently drank large amounts of alcohol.
Multum habit

Levorphanol may be habit forming and should be used only by the person for whom it was prescribed. Never share levorphanol with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Multum nopreg

FDA pregnancy category C. It is not known whether levorphanol will harm an unborn baby. Levorphanol may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using levorphanol.

Multum nobrfeed

It is not known whether levorphanol passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using levorphanol.

Multum nochild

Do not give this medication to anyone under 18 years old without medical advice.

Serious side effects may be more likely in older adults taking levorphanol.

How should I take levorphanol?

Take exactly as prescribed. Never take levorphanol in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Your doctor may occasionally change your dose to make sure you get the best results.

Multum food

Take levorphanol with food or milk if it upsets your stomach.

Multum donot

Do not stop using levorphanol suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using levorphanol.

Multum rt

Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Levorphanol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Since levorphanol is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of levorphanol can be fatal.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking levorphanol?

Multum noalcohol

Do not drink alcohol while you are using this medication. Dangerous side effects or death can occur when alcohol is combined with levorphanol. Check your food and medicine labels to be sure these products do not contain alcohol.

Multum dizzy

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how levorphanol will affect you.

Multum dizzy

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

What are the possible side effects of levorphanol?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • mood changes, confusion, unusual thoughts or behavior;
  • thoughts of suicide or hurting yourself;
  • feeling like you might pass out;
  • weak or shallow breathing;
  • cold, clammy skin;
  • blue lips or skin;
  • painful or difficult urination; or
  • slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious side effects are more likely to occur, such as:

  • dizziness, drowsiness;
  • nausea, vomiting, constipation, stomach pain;
  • dry mouth;
  • double vision;
  • itching, sweating; or
  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect levorphanol?

Multum dizzy

You should not take levorphanol with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result. Tell your doctor if you regularly use any of these medications, or medicine for seizures, depression, or anxiety.

Tell your doctor about all other medicines you use, especially:

  • pentazocine (Talwin);
  • nalbuphine (Nubain);
  • butorphanol (Stadol); or
  • buprenorphine (Buprenex, Butrans, Subutex).

There may be other drugs that can interact with levorphanol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about levorphanol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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