Health Encyclopedia > Medications

progesterone

Pronunciation: proe JESS te rone

Brand: First Progesterone MC10, First Progesterone MC5, Progest, Prometrium

Prometrium 100 mg

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Prometrium 200 mg

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What is the most important information I should know about progesterone?

Multum nopreg

Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Multum donot

Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy.

Using progesterone can increase your risk of blood clots, stroke, heart attack, or breast cancer.

Multum donot

Do not use this medication if you have any of the following conditions: a history of breast cancer, abnormal vaginal bleeding, liver disease, if you are pregnant, or if you have had a stroke, heart attack, or blood clot within the past year.

Progesterone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

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Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Progesterone should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.

What is progesterone?

Progesterone is a female hormone important for the regulation of ovulation and menstruation.

Progesterone is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Progesterone should not be used to prevent heart disease or dementia, because this medication may actually increase your risk of developing these conditions.

Progesterone may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using progesterone?

Multum donot

Some forms of this medication may contain peanut oil. Do not use progesterone without telling your doctor if you have a peanut allergy.

Multum donot

Do not use progesterone if you have:

  • a history of breast cancer;
  • abnormal vaginal bleeding that a doctor has not checked;
  • liver disease;
  • if you are pregnant; or
  • if you have had a stroke, heart attack, or blood clot within the past year.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use progesterone:

  • heart disease, circulation problems;
  • risk factors for coronary artery disease (such as smoking, being overweight, and having high blood pressure or high cholesterol);
  • migraines,
  • asthma;
  • kidney disease;
  • seizures or epilepsy;
  • a history of depression; or
  • diabetes.
Multum nopreg

Do not use progesterone without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

Multum nobrfeed

Progesterone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use progesterone?

Use this medication exactly as it was prescribed for you. Do not use larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

Progesterone is sometimes given for only a short period of time, such as 6 to 12 days at a time during each menstrual cycle. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Multum water

Take the pill form of progesterone with a full glass of water.

Apply progesterone cream to the skin as directed by your doctor.

Progesterone injection is given as a shot into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection. You may be given instructions on how to use your injections at home. Do not use this medicine at home if you do not fully understand how to give the injection and properly dispose of needles and syringes used in giving the medicine.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using progesterone.

Your doctor will need to see you on a regular basis while you are using this medication. Do not miss any scheduled appointments.

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Store progesterone at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

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Call your doctor if you miss more than one dose of this medication.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using progesterone?

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Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of progesterone?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • sudden numbness or weakness, especially on one side of the body;
  • sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance;
  • fast or pounding heartbeats;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • unusual or unexpected vaginal bleeding;
  • migraine headache;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • swelling in your hands, ankles, or feet;
  • fever, chills, body aches, flu symptoms;
  • a breast lump; or
  • symptoms of depression (sleep problems, weakness, mood changes).

Less serious side effects may include:

  • mild nausea, diarrhea, bloating, stomach cramps;
  • dizziness, spinning sensation;
  • hot flashes;
  • mild headache;
  • joint pain;
  • breast pain or tenderness;
  • cough;
  • acne or increased hair growth;
  • changes in weight; or
  • vaginal itching, dryness, or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect progesterone?

There may be other drugs that can interact with progesterone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about progesterone.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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