Health Encyclopedia > Medications

telavancin

Pronunciation: TEL a VAN sin

Brand: Vibativ

What is the most important information I should know about telavancin?

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Before using this medication, tell your doctor if you are pregnant. You may need a pregnancy test to determine whether you are pregnant before you start using telavancin.

If you are not pregnant before you start using telavancin, use effective birth control to prevent pregnancy during treatment. Any woman who could possibly become pregnant should use birth control during treatment with telavancin.

If you are a woman using telavancin, you are considered able to become pregnant unless you have ovarian failure, have had a tubal ligation or hysterectomy, or have been in menopause or not had a menstrual period in 2 years.

Telavancin can be harmful to the kidneys, and this effect is increased when telavancin is used together with other medicines that can harm the kidneys. Before using telavancin, tell your doctor if you are receiving chemotherapy, or using medicines to treat a bowel disorder, medication to prevent organ transplant rejection, antiviral medications, pain or arthritis medicines, a diuretic (water pill), or any other injected antibiotics.

If you have kidney disease, you may need a dose adjustment or special tests to safely use telavancin.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Telavancin will not treat a viral infection such as the common cold or flu.

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Call your doctor right away if you have a serious side effect such as watery or bloody diarrhea, confusion, thirst, swelling, feeling short of breath, or urinating less than usual or not at all

What is telavancin?

Telavancin is an antibiotic that treats infection caused by bacteria.

Telavancin is used to treat severe skin infections.

Telavancin may also be used for other purposes not listed in this medication guide.

What should I discuss with my health care provider before using telavancin?

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You should not use this medication if you are allergic to it.

If you have kidney disease, you may need a dose adjustment or special tests to safely use telavancin.

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FDA pregnancy category C. It is not known whether telavancin is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant. You may need a pregnancy test to determine whether you are pregnant before you start using telavancin.

Your name may need to be listed on a pregnancy registry if you use telavancin while you are pregnant. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether telavancin had any effect on the baby.

If you are not pregnant before you start using telavancin, use effective birth control to prevent pregnancy during treatment. Any woman who could possibly become pregnant should use birth control during treatment with telavancin.

If you are a woman using telavancin, you are considered able to become pregnant unless you have ovarian failure, have had a tubal ligation or hysterectomy, or have been in menopause or not had a menstrual period in 2 years.

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It is not known whether telavancin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is telavancin given?

Telavancin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Telavancin must be given slowly through an IV infusion, and can take at least 1 hour to complete.

This medication is usually given once every 24 hours for 7 to 14 days. Follow your doctor's instructions.

Telavancin powder must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

Each single-use vial (bottle) of this medicine is for one use only. Throw away the vial after one use, even if there is still some medicine left in it after injecting your dose.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Telavancin will not treat a viral infection such as the common cold or flu.

To be sure this medication is not causing harmful effects, your kidney function will need to be checked with blood tests on a regular basis. Do not miss any follow-up visits to your doctor.

Telavancin can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using telavancin.

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Store telavancin powder in the refrigerator. Do not freeze.

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After mixing telavancin with a diluent, you may store the mixture in the refrigerator and use it within 72 hours. Do not freeze.

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Mixed medicine may also be stored at room temperature, but you must then use it within 4 hours after mixing.

Do not use the mixed medication if it has changed colors or has any particles in it. Mix a new dose.

What happens if I miss a dose?

Contact your doctor for instructions if you miss a dose of this medication.

What happens if I overdose?

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Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, increased thirst, vomiting, swelling, and urinating less than usual or not at all.

What should I avoid while using telavancin?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, stop taking this medication and call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

What are the possible side effects of telavancin?

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Some people receiving a telavancin injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your doctor right away if you feel itchy or tingly, or have a red rash on your upper body during the injection.

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have a serious side effect such as:

  • diarrhea that is watery or bloody;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
  • swelling, weight gain, feeling short of breath; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • nausea, vomiting, diarrhea, stomach pain, loss of appetite;
  • chills or shivering;
  • headache, dizziness;
  • foamy appearance in your urine;
  • unusual or unpleasant taste in your mouth;
  • vaginal itching or discharge;
  • mild skin rash or itching; or
  • redness or pain around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect telavancin?

Telavancin can be harmful to the kidneys, and this effect is increased when telavancin is used together with other medicines that can harm the kidneys. Before using telavancin, tell your doctor if you are receiving chemotherapy, or using medicines to treat a bowel disorder, medication to prevent organ transplant rejection, antiviral medications, pain or arthritis medicines, a diuretic (water pill), or any other injected antibiotics.

Tell your doctor about all other medications you use, especially:

  • arsenic trioxide (Trisenox);
  • droperidol (Inapsine);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), or pentamidine (NebuPent, Pentam);
  • an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), or desipramine (Norpramin);
  • anti-malaria medications such as chloroquine (Arelan), or mefloquine (Lariam);
  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G), or sotalol (Betapace);
  • medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);
  • migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or
  • narcotic medication such as levomethadyl (Orlaam), or methadone (Dolophine, Methadose).

This list is not complete and there may be other drugs that can interact with telavancin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about telavancin.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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