Vincristine is a plant-based compound and is classified as an
alkylating agent. It causes cell death by interfering with the way genetic
material (DNA) in the cell multiplies.
Vincristine is only available as an intravenous (IV) medicine.
The type and extent of a disease determines the exact dose and schedule of
administering this medicine.
Vincristine is effective against many forms of cancer,
Vincristine is effective against many forms of cancer. It is
usually used in combination with other chemotherapy medicines.
Side effects are common with vincristine and can include:
Women who take this medicine may experience menopausal symptoms,
including hot flashes and vaginal dryness.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
Vincristine should be administered only under the supervision of a
If vincristine leaks into the tissue around the vein, it can damage
the tissue in that area. Tell your doctor or nurse immediately if you notice
any stinging or burning around the vein while the medicine is being given.
You may not be able to become pregnant or father a child after
taking vincristine. Discuss fertility with your doctor before starting
treatment with this drug.
Vincristine can cause birth defects. Do not use this medicine if
you are pregnant or if you wish to become pregnant or father a child while you are
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
March 29, 2012
Anne C. Poinier, MD - Internal Medicine
& Douglas A. Stewart, MD - Medical Oncology
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