Uterine artery embolization


Definition

Uterine artery embolization (UAE) is a procedure to treat fibroids without surgery. Uterine fibroids are noncancerous (benign) tumors that develop in the uterus (womb).

During the procedure, the blood supply of the fibroids is cut off, causing the fibroids to shrink.


Alternative Names

Uterine fibroid embolization; UFE; UAE


Description

UAE is done by a doctor called an interventional radiologist.

You will be awake but unable to feel pain. (This is called conscious sedation.) The procedure takes about 45 - 60 minutes.

The procedure is usually done this way:

  • You will receive a sedative, a medicine that will make you relaxed and sleepy.
  • A local anesthetic (pain-killer) will be applied to your skin around your groin. This will numb the area so you do not feel pain.
  • The radiologist will make a 1/8-inch-long incision (cut) in your skin. Then the radiologist will insert a catheter (a thin tube) into your femoral artery. This artery is at the top of your leg. Next the radiologist will thread the catheter into your uterine artery. This artery supplies blood to the uterus.
  • Small plastic or gelatin particles will be injected through the catheter into the blood vessels that supply blood to the fibroids. These particles block the blood supply to the tiny arteries that carry blood to the fibroids. Without this blood supply, the fibroids shrink and then die.
  • UAE will be done in both your left and right uterine arteries, using only one incision (cut). If needed, multiple fibroids can be treated.

Why the Procedure Is Performed

UAE is an effective way to treat symptoms caused by fibroids.

  • Symptoms may include bleeding, low blood count, pelvic pain or pressure, waking up at night to urinate, and constipation.
  • Treatment of the fibroids with medications or hormones will almost always have been tried before you have this procedure.
  • Sometimes women have UAE after childbirth to treat very heavy vaginal bleeding.

References

ACOG Practice Bulletin: Clinical management guidelines for obstetricians-gynecologists. Number 96, August 2008. Obstet Gynecol. 2008;112:387-400.

Bradley L, Uterine Fibroid Embolization: a viable alternative to hysterectomy. Obstet Gynecol. 2009:127-135.

Goodwin SC, Spies JB, Worthington-Kirsch R et al. Uterine artery Embolization for treatment of leiomyomata: long term outcomes from the FIBROID registry. Obstet Gynecol. 2008; 111:22-33.

Tulandi T, Salamah K, Fertility and Uterine Artery Embolization. Obstet Gynecol. 2010;115:857-860.

Volkers NA, Hehenkamp WJ, Birnie E, Ankum WM, Reekers JA. Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids: 2 years' outcome from the randomized EMMY trial. Am J Obstet Gynecol. 2007 Jun;196(6):519.e1-11.


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Review Date: 10/12/2010
Reviewed By: A.D.A.M. Editorial Team: David Zieve, MD, MHA, and David R. Eltz. Previously reviewed by Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine (2/7/2009).
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