Agitation


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Definition

Agitation is an unpleasant state of extreme arousal (stirred up or excited), increased tension, and irritability.


Alternative Names

Restlessness


Considerations

Agitation can come on suddenly or over time. It can last for just a few minutes, or for weeks and even months. Pain, stress, and fever can all increase agitation.

Agitation by itself may not be a sign of a health problem. However, if other symptoms occur, it can be a sign of disease.

When agitation lasts for hours and there is a change in alertness (altered consciousness), doctors call this delirium. Delerium always has a medical cause.


Common Causes

There are many causes of agitation, some of which include:

  • Alcohol intoxication or withdrawal
  • Caffeine intoxication
  • Intoxication or withdrawal from drugs of abuse (such as cocaine, marijuana, hallucinogens, PCP, or opiates)
  • Hospitalization (older adults often have delirium while in the hospital)
  • Hyperthyroidism (overactive thyroid gland)
  • Infection (more often in elderly people)
  • Medical tests that involve injecting a "contrast medium" into the patient
  • Nicotine withdrawal
  • Theophylline or other medicines
  • Vitamin B6 deficiency

Agitation can occur with brain and mental health disorders, such as:


References

Park JM, Park L, Prager LM. Emergency psychiatry. In: Stern TA, Rosenbaum JF, Fava M, Biederman J, Rauch SL, eds. Massachusetts General Hospital Comprehensive Clinical Psychiatry. 1st ed. Philadelphia, Pa: Mosby Elsevier;2008:chap 87.

Rossi J, Swan MC, Isaacs ED. The violent or agitated patient. Emerg Med Clin North Am. 2010;28:235-256.


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Review Date: 2/28/2010
Reviewed By: Linda Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Michelle Benger Merrill, MD, Instructor in Clinical Psychiatry, Department of Psychiatry, Columbia University Medical Center, New York, NY. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 5/12/2011
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