Mouth Sores


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Definition

Different types of sores can appear anywhere in the mouth, including the inner cheeks, gums, tongue, lips, or palate.

Alternative Names

Aphthous stomatitis


Common Causes

Mouth sores may be caused by irritation from:

  • A sharp or broken tooth or poorly fitting dentures
  • Biting your cheek, tongue, or lip
  • Burning your mouth from hot food or drinks
  • Braces
  • Chewing tobacco

Cold sores are caused by the herpes simplex virus and are very contagious. Usually, you will have tenderness, tingling, or burning before the actual sore appears. Cold sores usually begin as blisters and then crust over.  The herpes virus can live in your body for years. It only appears as a mouth sore when something triggers it, such as:

  • Another illness, especially if there is a fever
  • Hormone changes (such as menstruation)
  • Stress
  • Sun exposure

Canker sores are NOT contagious. They can appear as a single pale or yellow ulcer with a red outer ring, or as a cluster of these sores. Women seem to get them more than men. The cause of canker sores is not clear, but may be related to:

  • A weakness in your immune system (for example, from the cold or flu)
  • Hormone changes
  • Stress
  • Lack of certain vitamins and minerals in the diet, including vitamin B12 or folate

Less commonly, mouth sores can be a sign of an illness, tumor, or reaction to a medication. This can include:

  • Autoimmune disorders (including systemic lupus erythematosus)
  • Bleeding disorders
  • Cancer of the mouth
  • Infections such as hand-foot-mouth disease
  • Weakened immune system -- for example, if you have AIDS or are taking medication after a transplant

     

Drugs that may cause mouth sores include aspirin, chemotherapy, penicillin, sulfa drugs, and phenytoin (used for seizures)


References

Daniels TE. Diseases of the mouth and salivary glands.In: Goldman L, Schafer AI, eds.Cecil Medicine. 24th ed.Philadelphia,PA: Saunders Elsevier; 2011:chap 433.


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Review Date: 11/13/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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