Seizures


Definition

A seizure is the physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain.

The term "seizure" is often used interchangeably with "convulsion." Convulsions are when a person's body shakes rapidly and uncontrollably. During convulsions, the person's muscles contract and relax repeatedly. There are many different types of seizures. Some have mild symptoms and no body shaking.

See also:

  • Generalized tonic clonic seizure
  • Partial (focal) seizure
  • Petit mal (absence) seizure
  • Epilepsy
  • Fever (febrile) convulsions (seizures in children with high fever)

Alternative Names

Secondary seizures; Reactive seizures; Seizure - secondary; Seizure - reactive; Convulsions


Considerations

It may be hard to tell if someone is having a seizure. Some seizures only cause a person to have staring spells. These may go unnoticed.

Specific symptoms depend on what part of the brain is involved. They occur suddenly and may include:

  • Brief blackout followed by period of confusion (the person cannot remember a period of time)
  • Changes in behavior such as picking at one's clothing
  • Drooling or frothing at the mouth
  • Eye movements
  • Grunting and snorting
  • Loss of bladder or bowel control
  • Mood changes such as sudden anger, unexplainable fear, panic, joy, or laughter
  • Shaking of the entire body
  • Sudden falling
  • Tasting a bitter or metallic flavor
  • Teeth clenching
  • Temporary halt in breathing
  • Uncontrollable muscle spasms with twitching and jerking limbs

Symptoms may stop after a few seconds minutes, or continue for 15 minutes. They rarely continue longer.

The person may have warning symptoms before the attack, such as:

  • Fear or anxiety
  • Nausea
  • Vertigo
  • Visual symptoms (such as flashing bright lights, spots, or wavy lines before the eyes)

Common Causes

Seizures of all types are caused by disorganized and sudden electrical activity in the brain.

Causes of seizures can include:

  • Abnormal levels of sodium or glucose in the blood
  • Brain infection, including meningitis
  • Brain injury that occurs to the baby during labor or childbirth
  • Brain problems that occur before birth (congenital brain defects)
  • Brain tumor (rare)
  • Choking
  • Drug abuse
  • Electric shock
  • Epilepsy
  • Fever (particularly in young children)
  • Head injury
  • Heart disease
  • Heat illness (see heat intolerance)
  • High fever
  • Illicit drugs, such as angel dust (PCP), cocaine, amphetamines
  • Kidney or liver failure
  • Low blood sugar
  • Phenylketonuria (PKU), which can cause seizures in infants
  • Poisoning
  • Stroke
  • Toxemia of pregnancy
  • Uremia related to kidney failure
  • Very high blood pressure (malignant hypertension)
  • Venomous bites and stings (see snake bite)
  • Use of illegal street drugs, such as cocaine or amphetamines
  • Withdrawal from alcohol after drinking a lot on most days
  • Withdrawal from certain drugs, including some painkillers and sleeping pills
  • Withdrawal from benzodiazepines (such as Valium)

Sometimes no cause can be identified. This is called idiopathic seizures. They usually are seen in children and young adults but can occur at any age. There may be a family history of epilepsy or seizures.

If seizures repeatedly continue after the underlying problem is treated, the condition is called epilepsy.


References

Duvivier EH, Pollack CV Jr. Seizures. In: Marx JA, ed. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa: Mosby Elsevier; 2009:chap 100.

Krumholz A, Wiebe S, Gronseth G, et al. Practice parameter: evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2007;69(21):1991-2007.

Rubin DH, Kornblau DH, Conway EE Jr, Caplen SM. Neurologic Disorders. In: Marx JA, ed. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 7th ed. Philadelphia, Pa: Mosby Elsevier; 2009:chap 173.

Walker SP, Permezel M, Berkovic SF. The management of epilepsy in pregnancy. BJOG. 2009 May;116(6):758-67.


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Review Date: 2/16/2012
Reviewed By: Luc Jasmin, MD, PhD, Department of Neurosurgery at Cedars-Sinai Medical Center, Los Angeles, and Department of Anatomy at UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Health Solutions, Ebix, Inc.
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Last Updated 4/17/2012
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