Skin Discoloration - Bluish


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Definition

Cyanosis is a bluish color to the skin or mucus membranes that is usually due to a lack of oxygen in the blood.


Alternative Names

Lips - bluish; Fingernails - bluish; Cyanosis; Bluish lips and fingernails; Bluish skin


Considerations

Red blood cells provide oxygen to body tissues. Most of the time, almost all blood cells carry a full supply of oxygen. These blood cells are bright red, and the skin has a pinkish or red hue.

Blood that has lost its oxygen is dark bluish-red. People whose blood is low in oxygen tend to have a bluish color to their skin, called cyanosis.

Depending on the cause, cyanosis may develop suddenly, along with shortness of breath and other symptoms.

Cyanosis that is caused by long-term heart or lung problems may develop slowly. Symptoms may be present, but are often not severe.

When oxygen levels have dropped only a small amount, cyanosis may be hard to detect.

In dark-skinned people, cyanosis may be easier to see in the mucus membranes (lips, gums, around the eyes) and nails.


Common Causes

Cyanosis that is seen in only one part of the body may be due to:

LACK OF OXYGEN IN THE BLOOD

Most cyanosis occurs because of a lack of oxygen in the blood. This can be caused by the following problems.

Problems with the lungs:

Problems with the airways leading to the lungs:

Problems with the heart:

  • Heart failure
  • Heart defects that are present at birth (congenital)
  • Heart stops working (cardiac arrest)

Other problems:

  • Drug overdoses (narcotics, benzodiazepines, sedatives)
  • Exposure to cold air or water
  • Toxins such as cyanide

References

Kraft M. Approach to the patient with respiratory disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 83.

Schwartzstein RM, Adams L. Dyspnea. In: Mason RJ, Broaddus VC, Martin TR, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 28.


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Review Date: 5/25/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Last Updated 7/12/2011
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