Swelling


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Definition

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks).

Swelling can occur all over the body (generalized) or only in one part of the body (localized).

See also:

  • Angioedema
  • Ankle, feet, and leg swelling
  • Breast enlargement
  • Facial swelling
  • Joint swelling
  • Scrotal swelling
  • Swelling in the abdomen
  • Swollen glands
  • Swollen gums

Alternative Names

Edema; Anasarca


Considerations

Slight swelling (edema) of the lower legs is common in warm summer months, especially if a person has been standing or walking a lot.

General swelling, or massive edema (also called anasarca), is a common sign in people who are very sick. Although slight edema may be hard to detect, a large amount of swelling is very obvious.

Edema is described as pitting or non-pitting.

  • Pitting edema leaves a dent in the skin after you press the area with a finger for about 5 seconds. The dent will slowly fill back in.
  • Non-pitting edema does not leave this type of dent when pressing on the swollen area.

Common Causes

  • Acute glomerulonephritis
  • Burns, including sunburn
  • Chronic kidney disease
  • Heart failure
  • Liver failure from cirrhosis
  • Nephrotic syndrome
  • Poor nutrition
  • Pregnancy
  • Thyroid disease
  • Too little albumin in the blood (hypoalbuminemia)
  • Too much salt or sodium
  • Use of certain drugs, including
    • Androgenic and anabolic steroids
    • Calcium channel blockers
    • Certain blood pressure medicines
    • Corticosteroids such as prednisone
    • Diabetes medicines called thiazolidinediones
    • Estrogen
    • Nonsteroidal anti-inflammatory drugs (NSAIDs)

References

Mitchell RN. Hemodynamic disorders, thromboembolic disease, and shock. In: Kumar V, Abbas AK, Fausto N, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, Pa:Saunders Elsevier;2009:chap 4.

Clein LJ. Edema. In: Walsh D, Caraceni AT, Fainsinger R, et al, eds. Palliative Medicine. 1st ed. Philadelphia, Pa: Saunders Elsevier;2008:chap 160.


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Review Date: 10/28/2010
Reviewed By: Linda Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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