Health Encyclopedia

Rheumatoid Factor (RF)

Rheumatoid Factor (RF)

Rheumatoid factor (RF) is a protein (antibody) made by the immune system that can attack the body's own tissues. An elevated rheumatoid factor may mean the presence of an inflammatory disease.

Rheumatoid factor can be measured with a blood test. This is most helpful for diagnosing rheumatoid arthritis, lupus, and Sjögren's syndrome. Certain heart and liver diseases, infectious diseases (such as tuberculosis), and normal aging may also increase RF levels.

Last Revised: June 5, 2012

Author: Healthwise Staff

Medical Review: Susan C. Kim, MD - Pediatrics & John Pope, MD - Pediatrics

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

© 1995-2013 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.