In a major breakthrough, mutations in a gene called apolipoprotein L1 (APOL1) were found to be associated with a family of common kidney diseases in African-Americans.
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The kidneys filter the blood and help remove waste and extra fluid from the body, in addition to controlling the chemical balance of the body. The kidneys also play a role in regulating blood pressure, and kidney disease may lead to the development of high blood pressure (hypertension). As with other organs, kidney function may be slightly reduced with aging.
The kidneys are part of the urinary system, which also includes the ureters and the bladder. Bladder control can be affected by muscle changes and changes in the reproductive system.
Kidney disease is classified as any disease or disorder that affects the function of the kidneys. This may include:
There are several tests and procedures that are standard in the diagnosis and treatment of kidney diseases.
Tests:
Renal scanRenal biopsyDialysisHemodialysisKidney function testIntravenous pyelogramUrinalysisUrinary castsAnti-glomerular basement membraneRenal perfusion scintiscanFractional excretion of sodiumRenal arteriographyProtein-urineUreteral retrograde brush biopsy cytologyAbdominal CT scanAbdominal MRIBUNUrine concentration test
Procedures:
Kidney transplant
Kidney removal
Lithotripsy
Millions of Americans in the early stages of chronic kidney disease (CKD) are at an increased risk of having atrial...
Kidney disease is a growing public health problem, with approximately half a million individuals in the United States...
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e.g., "allergy," "diabetes"
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