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Gout and Kidney Disease

Gout is a common disease caused by a buildup of uric acid in the bloodstream. The uric acid can deposit in joints and cause gout.

Gout is more common in kidney disease because the body has difficulty getting rid of uric acid in the urine.

There are several types of inherited kidney disease that are associated with a high frequency of gout.  These conditions are studied by the Rare Inherited Kidney Disease Research Team at Wake Forest School of Medicine, led by Anthony Bleyer, M.D., M.S., a professor in the Section on Nephrology. 

The conditions that cause gout and kidney disease include uromodulin kidney disease and inherited kidney disease due to mutations in renin. 

These conditions are associated with gout and progressive kidney disease.  These conditions are inherited, often with many family members affected.  Sometimes, only a parent and child are affected in a family.

Our research team has been studying these conditions for over 20 years.  If you think you may have one of these conditions, please contact Dr. Bleyer at

Also, see our website on this disorder at clicking here.

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Last Updated: 08-25-2016
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Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

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