Wake Forest Baptist Researchers Awarded $3.4 Million Grant to Study Cardiovascular Risk in Breast Cancer Survivors
WINSTON-SALEM, N.C. – Nov. 19, 2015 – Wake
Forest Baptist Medical Center has received a $3.4 million grant for a multi-site clinical trial to study cardiovascular decline following
successful chemotherapy to treat Stage I-III breast cancer patients.
Investigator and Professor of Cardiology at Wake Forest Baptist, W.
Gregory Hundley, M.D. explains, “Though chemotherapy and early
detection methods have greatly increased survival rates for women with breast
cancer, this progress is threatened by a significant increase in cardiovascular
events for survivors. This study will test cardiovascular function, exercise
capacity and fatigue in 1,000 survivors and aims to determine the risk of
future cardiac events. We hope that after this study we will better understand
who is at risk and how to prevent future cardiovascular damage in breast cancer
is understood about the origins of cardiovascular dysfunction, exercise
intolerance, or fatigue in these women, and current risk prediction models for cardiovascular
events do not include breast cancer treatment.
The hope is that this research will reduce the
gaps in knowledge associated with cancer treatment-related cardiovascular
injury and prompt development of new risk prediction models to prevent cardiovascular
events in breast cancer survivors for the purpose of improving
overall survival in women with breast cancer.
five-year grant from the National Cancer Institute (NCI) and the NCI’s
Community Oncology Research Program (NCORP), allows researchers across the
country to collect the large amount of data necessary for this study through
NCORP’s nationwide network of community and academic hospitals and, more
importantly, allows study participants to be close to home, family and friends.11/19/2015http://www.wakehealth.edu/News-Releases/2015/Wake_Forest_Baptist_Researchers_Awarded_$3_4_Million_Grant_to_Study_Cardiovascular_Risk_in_Breast_Cancer_Survivors.htm
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