Medical Expert - Glenn J. Lesser, MD

Area of Expertise: Cancer - Brain
Area of Expertise: Cancer - Pain Management
Area of Expertise: Cancer - Symptom Management
Media Contact: Marguerite Beck
Media Office: 336-716-2415 Media Mobile: 336-480-8599
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Glenn J. Lesser, MD

Professor of Internal Medicine - Hematology and Oncology

Director, Medical Neuro-Oncology

Lesser's clinical and research interests include the development of novel therapeutic agents for the treatment of adult malignant brain tumors and the symptom management issues experienced by patients with cancer, including cancer-related pain, fatigue, nausea and vomiting, anemia, taste disturbances, and anorexia/weight loss. An active researcher, he has served as the principal investigator and lead author on phase I, II and III institutional and cooperative group neuro-oncology and symptom management clinical trials, and as a member of the research team/institutional principal investigator on more than 60 cooperative group and Medical Center clinical trials.

Lesser has published numerous articles in the peer-reviewed literature, and is a member of the editorial boards of the Journal of Clinical Oncology and Current Treatment Options in Oncology. He has served as the Director of Medical Neuro-oncology, Co-Principal Investigator of the Wake Forest University Community Clinical Oncology Program (CCOP) Research Base, member of the Executive Committee and the Internal Advisory Board of the Brain Tumor Center of Excellence, and the Wake Forest Principal Investigator for the National Cancer Institute (NCI)-funded Adult Brain Tumor Consortium. He is an elected member of the Physician Practice Council and the Medical Executive Committee and the Co-Chair of the Medical Center's Pain Management Task Force. Dr. Lesser is an invited member of the International Clinical Trials Advisory Panel for Cancer Research United Kingdom, the Data Safety Monitoring Board of the MD Anderson Collaborative Brain Tumor Trial network, the Medical Advisory Board of the National Brain Tumor Society, the Scientific Review Committee of the Collaborative Ependymoma Research Network (CERN), and the CALGB-NCCTG-ACOSOG Alliance neuro-oncology steering committee. He is a merit award recipient from the American Society of Clinical Oncology and is listed in Best Doctors in America.


Brain tumors, cancer pain, chemotherapy, experimental therapies


Novel Brain Tumor Vaccine Acts Like Bloodhound to Locate Cancer Cells

A national clinical trial testing the efficacy of a novel brain tumor vaccine has begun at Wake Forest Baptist Medical Center, the only facility in the Southeast to participate.

Wake Forest Baptist Cancer Center Awarded $18 Million by National Cancer Institute
WFBMC has received an $18 million, five-year grant from the NCI’s Community Oncology Research Program to design and conduct community-based, clinical trials.

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Area of Expertise: Cancer - Brain

Debinski, the director of the Brain Tumor Center of Excellence at Wake Forest Baptist, is a physician-scientist who pioneered a method to destroy malignant brain tumor cells without harming healthy cells. A drug developed by Debinski was an "unanticipated success" in early clinical trials

USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

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