Medical Expert - Michael A. Nader, PhD

Area of Expertise: Addiction Research
Media Contact: Marguerite Beck marbeck@wakehealth.edu
Media Office: 336-716-2415 Media Mobile: 336-480-8599
Patient Contact: Health On-Call® 1-800-446-2255

Michael A. Nader, PhD

Professor of Physiology and Pharmacology

Nader is an expert on how drugs of abuse affect the brain and has studied the problem of cocaine addiction for more than 20 years with grants from the National Institute on Drug Abuse. The cocaine abuse research by Nader and his colleagues is unique in that the Wake Forest primates are the only ones in the world that give themselves the drug and live in social groups, allowing researchers to study how the reinforcing actions of cocaine are affecting social behavior and the brain. Nader's research combines positron emission tomography (PET) imaging to examine levels of dopamine and nicotine receptor activity, as well as glucose activity in the brain. Most recently, Nader's group has been examining sex differences in vulnerability to cocaine abuse and found significant sex differences in how social rank (being dominant or subordinate) affects brain function and cocaine reinforcement. Nader and colleagues are looking at the effect of long-term cocaine use on dopamine receptors, behavior, brain function and cognition. Nader is trying to identify drugs that could be used in fighting cocaine addiction that can also enhance cognitive performance and possess the least undesirable side effects.

Keywords

drug abuse, nonhuman primate models of cocaine abuse, brain imaging, behavioral pharmacology, behavioral neuroscience, neuropharmacology addiction, addiction to prescription drugs

IN THE NEWS

Long-term ADHD Drug Use Appears Safe
Drugs used to treat Attention Deficit Hyperactivity Disorder (ADHD) do not appear to have long-term effects on the brain, according to new animal research from Wake Forest Baptist Medical Center.
Wake Forest Baptist March Awards and Recognitions
Wake Forest Baptist March Awards and Recognitions

Related Experts

David P. Friedman, PhD
Professor of Physiology and Pharmacology
Area of Expertise: Addiction Research

Holding faculty appointments in both physiology/pharmacology and general surgery, Friedman is a neuroscientist who has worked in the drug abuse field for more than 15 years. He is an expert on how drugs of abuse affect the brain and making new scientific findings accessible to lay


USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.