Medical Expert - Gary G. Schwartz, PhD, MPH., PhD.

Area of Expertise: Cancer - Prostate
Media Contact: Marguerite Beck marbeck@wakehealth.edu
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Gary G. Schwartz, PhD, MPH., PhD.

Associate Professor, Cancer Biology

Schwartz' principal research interest involves epidemiologic and translational studies (studies of screening and therapeutic trials) concerning the roles of vitamin D and other calciotrophic hormones in the natural history of prostate cancer. His other interests include the investigation of cancers of unknown etiology, e.g., testicular and pancreatic cancer. Schwartz' research has led to new understanding of the roles of calcium and vitamin D in the etiology of prostate cancer. His recent research has shown that some elevations in prostate-specific antigen (PSA) levels in men may be caused by a hormone normally occurring in the body (parathyroid hormone) and thus are not necessarily a predictor of the need for prostate biopsy. In 1990, Schwartz first proposed a link between vitamin D deficiency and prostate cancer when he noticed that the people most likely to die from prostate cancer were African Americans, followed by Scandinavians. People living in northern latitudes, where the angle of the sun is insufficient to generate vitamin D through the skin, are commonly vitamin D deficient, as are blacks. He is the author or co-author of more than 80 journal articles and book chapters and holds two patents on methods for screening for risk of pancreatic cancer and for predicting the risk of fatal prostate cancer. Dr. Schwartz has research support from the NCI, American Cancer Society, Lance Armstrong Foundation and other sources.

Keywords

metabolism, human, adult, translational research, cancer/oncogenesis, clinical trials, reproductive system, epidemiology/prevention, endocrine system

IN THE NEWS

Calcium Supplements May Not Prevent Bone Loss in Women with Breast Cancer

New research from Wake Forest Baptist Medical Center finds that the recommended daily doses of calcium and vitamin D supplements may not prevent loss of bone mineral density (BMD) in women undergoing breast cancer treatment.

 

Study Questions Value of Calcium and Vitamin D Supplements

New research from Wake Forest Baptist Medical Center epidemiologists shows that prescribing calcium and vitamin D supplements for men at risk of bone loss from hormonal treatment for prostate cancer does not prevent bone loss and, in fact, may increase the risk of cardiovascular disease and aggressive prostate cancer.

Study Shows High Blood Calcium Levels May Indicate Ovarian Cancer
A new study from Wake Forest Baptist Medical Center is the first to report that high blood calcium levels might predict ovarian cancer, the most fatal of the gynecologic cancers.

Related Experts

Lance D. Miller, PhD
Associate Professor, Cancer Biology
Area of Expertise: Cancer - Breast
Area of Expertise: Cancer - Prostate

Using genomic technologies such as DNA microarrays, Dr. Miller's laboratory investigates the transcriptional dynamics and genomic architectures of primary tumors to uncover novel prognostic biomarkers and mechanisms of disease progression.


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