Profile

Hossam Abdelnaby Shaltout, Ph.D.Wake Forest Baptist Health

Hossam Abdelnaby Shaltout, Ph.D.

Assistant Professor,

Contact Information

Email: hshaltou@wakehealth.edu

Insurance Accepted »

Additional Languages

Arabic

Education & Training

  • Ph.D., East Carolina University , 2005
Hossam Abdelnaby Shaltout, Ph.D.Wake Forest Baptist Health

Hossam Abdelnaby Shaltout, Ph.D.

Assistant Professor, Obstetrics & Gynecology
Hypertension and Vascular Research Center

Research Interests

hypertension, maternal & child health

Contact Information

Academic: 336-716-1251

Email: hshaltou@wakehealth.edu

Recent Publications

Chappell MC, Marshall AC, Alzayadneh EM, Shaltout HA, Diz DI. Update on the angiotensin converting enzyme 2-angiotensin (1-7)-Mas receptor axis: fetal programing, sex differences, and intracellular pathways. Front Endocrinol (Lausanne). 2014;4():201.

Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Response to angiotensin-(1-7) and bradykinin in baroreceptor reflex sensitivity in hypertension [letter]. Hypertension. 2013;61(2):e20.

Marshall AC, Shaltout HA, Nautiyal M, Rose JC, Chappell MC, Diz DI. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Peptides. 2013;44(C):25-31.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Differential expression of renin-angiotensin system components in the choroid plexus of betamethasone exposed and control sheep [abstract]. FASEB J. 2013;27(Meeting Abstracts):1107.12.

Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Reduction in central mitochondrial ROS improves cardiovagal baroreflex function independent of blood pressure in (mRen2)27 rats [abstract]. FASEB J. 2013;27(Meeting Abstracts):890.4.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. Am J Physiol Regul Integr Comp Physiol. 2013;305(7):R679-R688.


de Lima DC, Shaltout HA, Coimbra CC, Diz DI. Metabolic and cardiovascular adjustments to hemorrhage in [TGR(ASrAogen)] rats and (mRen2) 27 rats [abstract]. FASEB J. 2012;26(Meeting Abstracts):891.7.

Marshall AC, Shaltout HA, Nautiyal M, Chappell MC, Diz DI. Fetal betamethasone exposure and age influence the expression of AT7/mas receptors in the solitary tract nucleus [abstract]. FASEB J. 2012;26(Meeting Abstracts):1101.12.

Shaltout HA, Tooze JA, Rosenberger E, Kemper KJ. Time, touch, and compassion: effects on autonomic nervous system and well-being. Explore (NY). 2012;8(3):177-184.

Garcia-Espinosa MA, Shaltout HA, Gallagher PE, Chappell MC, Diz DI. In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats. J Cardiovasc Pharmacol. 2012;60(2):150-157.

Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats. Hypertension. 2012;60(5):1257-1265.

Marshall AC, Shaltout HA, Nautiyal M, Chappell MC, Diz DI. Fetal betamethasone exposure enhances the peptide ration of angiotensin II to angiotensin-(1-7) in the dorsal medulla of adult sheep [abstract]. Hypertension. 2012;60(Suppl 3):118.

Fortunato JE, Shaltout HA, Diz DI. Elevated supine arterial pressure in children with postural orthostatic tachycardia [abstract]. Hypertension. 2012;60(3 Suppl):304.

Shaltout HA, Fortunato JE, Diz DI. Negative effects of fludrocortisone treatment in adolescents with POTS and syncope [abstract]. Hypertension. 2012;60(3 Suppl):302.

Gwathmey TM, Shaltout HA, Rose JC, Diz DI, Chappell MC. Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney. Hypertension. 2011;57(3):620-626.

Diz DI, Arnold AC, Nautiyal M, Isa K, Shaltout HA, Tallant EA. Angiotensin peptides and central autonomic regulation. Curr Opin Pharmacol. 2011;11(2):131-137.

Arnold AC, Shaltout HA, Gilliam-Davis S, Kock ND, Diz DI. Autonomic control of the heart is altered in Sprague-Dawley rats with spontaneous hydronephrosis. Am J Physiol Heart Circ Physiol. 2011;300(6):H2206-2213.

Shaltout HA, Chappell MC, Rose JC, Diz DI. Exaggerated sympathetic mediated responses to behavioral or pharmacological challenges following antenatal betamethasone exposure. Am J Physiol Endocrinol Metab. 2011;300(6):E979-985.

Su Y, Shaltout HA, Figueroa JP, Chappell M, Rose JC. Effect of early glucocorticoid treatment on GR and MR expression in adult sheep kidney [abstract]. Reprod Sci. 2011;18(4 Suppl):220A.

Logan EM, Aileru AA, Shaltout HA, Averill DB, Diz DI. The functional role of PI3K in maintenance of blood pressure and baroreflex suppression in (mRen2)27 and mRen2.Lewis rat. J Cardiovasc Pharmacol. 2011;58(4):367-373.

Diz DI, Garcia-Espinosa MA, Shaltout HA, Olson J, Bourland JD, Groban L. Correlation of the brain medullary metabolites N-acetyl aspartic acid and N-acetyl aspartyl glutamate with the age related decline in sensitivity for baroreflex control of heart rate in humans [abstract]. Hypertension. 2011;58(5):e116.

de Lima DC, Shaltout HA, Coimbra CC, Diz DI. Hypercaloric diet impairs cardiovascular but not metabolic adjustments to hemorrhage in older [TGR (ASrAOGEN)] rats [abstract]. Hypertension. 2011;58(5):e164.

Fortunato JE, Diz DI, Shaltout HA. Fludrocortisone acetate improves baroreflex sensitivity and heart rate variability during tilt in children with postural orthostatic tachycardia syndrome [abstract]. Hypertension. 2011;58(5):e117.

Fortunato JE, Shaltout HA, Larkin MM, Rowe PC, Diz DI, Koch KL. Fludrocortisone improves nausea in children with orthostatic intolerance (OI). Clin Auton Res. 2011;21(6):419-423.

Marshall A, Shaltout HA, Nautiyal M, Arter A, Chappell MC, Diz DI. Localization and regulation of angiotensin receptor subtypes in sheep solitary tract nucleus: effects of in utero exposure to glucocorticoid [abstract]. Hypertension. 2011;58(5):e75.

Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Chronic intracerebroventricular angiotensin-(1-7) infusion, but not AT1 receptor blockade, improves vagal components of the baroreflex function in hypertensive (mRen2)27 transgenic rats [abstract]. Hypertension. 2011;58(5):e96.

Shaltout HA, Rose JC, Chappell MC, Diz DI. Ang-(1-7) deficiency and impairment of baroreflex for control of heart rate precede the antenatal betamethasone exposure-induced elevation in blood pressure [abstract]. Hypertension. 2011;58(5):e76.

Kemper KJ, Shaltout HA. Non-verbal communication of compassion: measuring psychophysiologic effects. BMC Complement Altern Med. 2011;11():132.

Fortunato JE Jr, Shaltout HA, Diz DI, Koch KL. Chronic idiopathic nausea in children associated with orthostatic intolerance improves after treatment with fludrocortisone [abstract]. Gastroenterology. 2011;140(5 Suppl 1):S-743.

Garcia-Espinosa MA, Shaltout HA, Olson J, Westwood BM, Robbins ME, Link K, Diz DI. Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function. Hypertension. 2010;55(2 Pt 2):487-493.

Gwathmey TM, Shaltout HA, Nixon PA, Rose JC, Washburn LK, Chappell MC. Antenatal steroid exposure is associated with reduced urinary ACE2 activity in adolescents [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):605.1.

Westwood B, Gwathmey T, Shaltout H, Diz D, Rose J, Chappell M. Immunocytochemical distribution of the Ang-(1-7)/mas receptor in the sheep kidney [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):605.6.

Arter A, Nautiyal M, Shaltout H, Chappell M, Diz D. Mas and AT1 receptor expression in adult sheep dorsomedial medulla [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):625.5.

Shaltout HA, Rose JC, Chappell MC, Diz DI. Modulation of baroreflex sensitivity by endogenous angiotensins in lamb solitary tract nucleus [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):624.7.

Gwathmey TM, Shaltout HA, Nixon PA, Rose JC, Washburn LK, Chappell MC. Sex and racial background influence angiotensin peptide metabolism in young adults [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):1024.31.

Shaltout HA, Rose JC, Figueroa JP, Chappell MC, Diz DI, Averill DB. Acute AT1-receptor blockade reverses the hemodynamic and baroreflex impairment in adult sheep exposed to antenatal betamethasone. Am J Physiol Heart Circ Physiol. 2010;299(2):H541-H547.

Arnold AC, Isa K, Shaltout HA, Nautiyal M, Ferrario CM, Chappell MC, Diz DI. Angiotensin-(1-12) requires angiotensin converting enzyme and AT1 receptors for cardiovascular actions within the solitary tract nucleus. Am J Physiol Heart Circ Physiol. 2010;299(3):H763-H771.

Shaltout HA, Rose JC, Chappell MC, Diz DI. Antenatal betamethasone exposure attenuates the functional role of angiotensin-(1-7) in the NTS [abstract]. Hypertension. 2010;56(5):e103.

Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension. 2009;53(2):404-408.

Gwathmey TM, Shaltout HA, Pendergrass KD, Pirro NT, Figueroa JP, Rose JC, Diz DI, Chappell MC. Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production. Am J Physiol Renal Physiol. 2009;296(6):F1484-1493.

Arnold AC, Shaltout HA, Gallagher PE, Diz DI. Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus. Hypertension. 2009;54(5):1001-1008.

Arnold AC, Shaltout HA, Gallagher PE, Diz DI. Protein phosphatase 1b activity in the solitary tract nucleus is necessary for normal baroreflex function [abstract]. Hypertension. 2009;54(4):e100.

Garcia-Espinosa MA, Shaltout HA, Olson J, Link K, Diz DI. In vivo proton magnetic resonance spectroscopy detection of neurotransmitter/metabolite concentrations in dorsomedial medulla as a noninvasive predictor of autonomic function [abstract]. Hypertension. 2009;54(4):e48.

Gwathmey TM, Pendergrass KD, Shaltout HA, Reid SD, Rose JC, Diz DI, Chappell MC. Steroid-induced fetal programming differentially alters nuclear angiotensin II receptor expression and function [abstract]. Hypertension. 2009;54(4):e42.

Shaltout HA, Diz DI, Figueroa JP, Chappell MC, Rose JC. Sympathetic nervous system mediated responses to behavioral or pharmacologic challenges are exaggerated as a result of antenatal betamethasone exposure [abstract]. Hypertension. 2009;54(4):e101`.

Shaltout HA, Figueroa JP, Rose JC, Chappell MC, Averill DB, Diz DI. Antenatal betamethasone causes alterations in angiotensin receptors in sheep brain in a gender specific manner [abstract]. FASEB J. 2009;23(1 Meeting Abstracts):941.11.

Arnold AC, Shaltout HA, Gallagher PE, Ganten D, Ferrario CM, Diz DI. Leptin impairs baroreflex sensitivity at the solitary tract nucleus: evidence for upregulation of leptin actions in animals with low brain angiotensinogen [abstract]. Hypertension. 2008;52(4):e50.

Garcia-Espinosa MA, Shaltout HA, Chappell MC, Gallagher PE, Ferrario CM, Ganten D, Reudelhuber TL, Diz DI. Angiotensin-(1-7) replacement gene transfer in the cisterna magna lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats [abstract]. Hypertension. 2008;52(4):e36.

Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Reduced renal ACE2 in fetal programmed hypertension [abstract]. Hypertension. 2008;52(4):e52.

Shaltout HA, Figueroa JP, Rose JC, Chappell MC, Averill DB, Diz DI. Evidence of Ang-(1-7) deficiency in antenatal betamethasone-treated young adult sheep [abstract]. Hypertension. 2008;52(4):e107.

Shaltout HA, Westwood BM, Averill DB, Ferrario CM, Figueroa JP, Diz DI, Rose JC, Chappell MC. Angiotensin metabolism in renal proximal tubules, urine and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol. 2007;292(1):F82-F91.

Shaltout HA, Figueroa JP, Rose JC, Chappell MC, Averill DB, Diz DI. Gender differences in the development of insulin resistance in adult sheep as result of antenatal betamethasone [abstract]. FASEB J. 2007;21(5 Pt I):A434.

Shaltout HA, Figueroa JP, Rose JC, Chappell M, Diz DI, Averill DB. Antenatal betamethasone causes angiotensin II-mediated impairment of cardiovascular function [abstract]. Hypertension. 2006;48(4):e32.

Shaltout HA, Figueroa JP, Rose JC, Chappell MC, Diz DI, Averill DB. Antenatal betamethasone causes angiotensin II-mediated impairment of baroreflex control of heart rate [abstract]. J Hypertens. 2006;24(Suppl 6):159.

Shaltout HA, Figueroa JP, Rose JC, Averill DB, Diz DI, Chappell MC. Increased blood pressure is associated with lower serum ACE2 activity and higher ACE activity following antenatal steroid exposure [abstract]. J Hypertens. 2006;24(Suppl 6):127.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Obstetrics & Gynecology

Quick Reference

Request an Appointment
New Patients

336-716-WAKE
888-716-WAKE

Existing patients may contact the clinic directly.
Find a Doctor Ways to Give
USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.