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• Physiology and Pharmacology
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• Allyn Howlett, PhD ›

Allyn Howlett, PhD - Publications

Howlett, A.C., Breivogel, C.S., Childers, S.R., Deadwyler, S.A., Hampson, R.E. and Porrino, L.J. (2004) Cannabinoid physiology and pharmacology: 30 years of progress.  Neuropharmacology 47S1:345-358.

Mukhopadhyay, S. and Howlett, A.C. (2005) Chemically distinct ligands promote differential CB₁ cannabinoid receptor-Gi protein interactions. Mol. Pharmacol. 67: 2016-2024.

Howlett, A.C., Mukhopadhyay, S. and Norford, D.C. (2006) Endocannabinoids and reactive nitrogen and oxygen species in neuropathologies. J. Neuroimmune Pharmacol. 1:305-316.

Ward, G.R., Franklin, S.O., Dempsey, K.T., Clodfelter, D.E., Gerald, T.M., Krissinger, D.J., Patel, K.M., Vrana, K.E. and Howlett, A.C. (2007) Glucocorticoids plus opioids up-regulate genes that influence neuronal function. Cell Mol. Neurobiol. 27:651-660.

Grace, C.R.R., Cowsik, S.M., Shim, J.-Y., Welsh, W.J., and Howlett, A.C. (2007) Conformation of a peptide mimetic of the fourth cytoplasmic loop of the CB₁ cannabinoid receptor. J. Structural Biol. 159:359-368.

Anavi-Goffer, S., Fleischer, D.,  Hurst, D. P., Lynch, D. L., Barnett-Norris, J., Shi, S., Lewis, D. L., Mukhopadhyay, S., Howlett, A.C., Reggio, P. H. and Abood, M. E. (2007)  Helix 8 Leu in the CB₁ Cannabinoid Receptor contributes to selective coupling with G proteins. J. Biol. Chem. 282:25100-13.

Niehaus, J.L., Liu, Y., Wallis, K.T., Egertova, M., Bhartur, S.G., Mukhopadhyay, S., Shi, S., He, H.,  Selley, D.E., Howlett, A.C., Elphick, M.R., and Lewis, D.L. (2007) CB₁ cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP1a. Mol. Pharmacol. 72: 1557-1566.

Jones, J.D., Carney, S.T., Vrana, K. E., Norford, D.C. and Howlett, A.C. (2008)  Cannabinoid receptor-mediated production of cyclic GMP and translocation of NO-sensitive guanylyl cyclase in neuronal cells. Neuropharmacology 54:23-30.

Padgett, L.W., Howlett, A.C. and Shim, J.-Y. (2008) Binding mode prediction of conformationally restricted anandamide analogs within the CB₁ receptor. J. Molec. Signaling 3:5.