Floyd “Ski” Chilton, PhD - Recent Publications
The Rewired Brain, Baker Books, 2016
Made to Crave Action Plan
Zondervan/ Harper Collins, 2011
The Gene Smart Diet,
Win the War Within, Rodale, 2006
Inflammation Nation, Simon and Schuster, 2005
Chosen from over 135 peer reviewed publications:
Sergeant S, Ruczinski I, Ivester P,
Lee TC, Morgan T, Nicklas BJ, Mathias RA,
Chilton FH. Impact of methods used to express levels of
circulating fatty acids on the degree and direction of associations with blood
lipids in humans. Brit J Nutr. 115(2):251-61,
Miller LR, Jorgensen MJ, Kaplan JR,
Seeds MC, Rahbar E, Morgan TM,
Welborn A, Chilton SM, Gillis J, Hester
A, Rukstalis M, and Sergeant S, Chilton
FH. Alterations in levels and ratios of n-3 and n-6
polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys
from birth to early adulthood. Physiol Behav 156:71-78, 2016.
Sergeant S, Rahbar E, and Chilton
FH. Gamma-linolenic acid, Dihommo-gamma linolenic acid, Eicosanoids
and Inflammatory Processes. Eur J Pharmacol 785:77-86, 2016.
Cui T, Hester AG,
Seeds MC, Rahbar E, Howard TD, Sergeant S, Chilton
FH. Impact of Genetic and Epigenetic
Variations Within the FADS Cluster on the Composition and Metabolism of
Polyunsaturated Fatty Acids in Prostate Cancer. Prostate 76(13):1182-91, 2016.
MathiasRA, SeedsMC, Pani V, Sergeant S, ChiltonFH. Genetic variants in the FADS gene: implications for
dietary recommendations for fatty acid intake. Curr Nutr Rep
Murphy RC, Wilson BA, Sergeant S, Ainsworth H, Seeds
MC and Mathias RA. Diet-gene interactions and PUFA metabolism:
a potential contributor to health disparities and human diseases. Nutrients. 6(5):1993-2022, 2014.
Howard TD, Mathias
RA, Seeds MC, Herrington DM, Hixson JE,
Shimmin LC, Hawkins GA, Sellers M, Ainsworth
HC, Sergeant S, Miller LR, and Chilton FH. DNA
methylation in an enhancer region of the FADS Cluster is associated with FADS
activity in human liver. PLoS ONE. May19;
9(5):e97510. doi: 10.1371/journal. pone. 0097510, 2014.
Hester GA, Murphy, RC, Uhlson CJ, Ivester P, Lee TC,
Sergeant S, Miller LR, Howard TD, Mathias RA, Chilton, FH. Relationship
between Common Variants in the Fatty Acid Desaturase (FADS) Cluster and
Eicosanoid Generation in Humans. J Biol Chem, Jun 24. pii:
Arm J, Boyce J, Chhay H, Dutile S, Wechsler M, Govindarajulu U, Ivester P,
Ainsworth H, Sergeant S, Chilton F and Israel E. LTC4 synthase
polymorphism modifies efficacy of botanical seed oil combination in asthma. Springerplus.
2014 3:661, 2014.
Lee TC, Ivester P, Sergeant S, Ainsworth H, Case DL, Morgan
T, Bowden DW, Chilton FH. The impact of polyunsaturated fatty
acid-based dietary supplements on disease biomarkers in a metabolic
syndrome/diabetes population. Lipids Health Dis.
K, Flynn DM, Jenkins KA, Wilson MD, Chilton
FH. Stearidonic and gamma-linolenic acids in echium oil improves glucose
disposal in insulin resistant monkeys. Prostaglandins Leukot
Essent Fatty Acids. 89(1):39-45, 2013.
Arm JP, Wang L, Chhay H, Zahid
M, Patil V, Govindarajulu U, Ivester P, Weaver KL, Israel E, Chilton
FH. Impact of a botanical oil combination (Echium plantagineum
and Borago officinalis) on leukotriene generation and pulmonary function
in asthmatics subjects. Lipids Health Dis.
12:141. doi: 10.1186/1476-511X-12-141, 2013.
Sergeant S,Hugenschmidt CE, Rudock ME,
Ziegler JT, Ivester P, Ainsworth, HC,
Vaidya D, Case LD, Langefeld CD, Freedman BI,
Bowden DW, Mathias RA, ChiltonFH. Differences in
arachidonic acid levels and fatty acid desaturase (FADS) in African Americans
and European Americans with diabetes/metabolic syndrome. Brit J Nutr 107:547,
Mathias RA, Fu W, Akey JM, Ainsworth HC, Torgerson DJ,
Ruczinski I, Sergeant S, Barnes KC, Chilton FH. Adaptive
evolution of the FADS gene cluster within Africa. PLoS ONE Sept
19; 7(9): e44926, 2012.
Mathias RA, Hugenschmidt CE, Sergeant S,
Torgerson DG, Ziegler JT, Ivester P, Case LD, Yanek LR, Bowden DW,
Freedman BI, Rudock ME, Becker LC, Langefeld CD, Becker DM, Barnes
KC, Chilton FH. The impact of FADS genetic variants on omega-6
polyunsaturated fatty acid metabolism in African Americans.BMC Genetics. May
20; 12(1):50, 2011.
Sergeant S, McQuail JE, Riddle D, Chilton FH, Ortmeier S, Jessup JA,
Groban L, Nicolle MM. Dietary fish oil
attenuates diastolic dysfunction, but has no effect on memory or brain measures
of inflammation in aged rats. J Gerontology: Biol Sci.May;66(5):521-33,
Chilton FH, Lee TC,
Willard SL, Ivester P, Sergeant S, Register TC, Shively SA. Depression and
altered serum lipids in cynomolgus monkeys on a Western diet.Physiol Behav.104:
Mathias RA, Vergara C, Gao L, Rafaels N, Hand T, Campbell
M, Bickel C, Ivester P, Sergeant S, Barnes KC, Chilton
FH. Association of fatty acid desaturase (FADS) gene cluster genetic
variants with omega-6 polyunsaturated fatty acid metabolism in a homogeneous
island population. J Lipid Res. Sept;51(9):2766-74, 2010.
Ivester P, Sergeant S, Danhauer SC, Case LD, Lamb A,
Chilton BG, Delar B, Hollingshead ML, Weaver KL, Chilton FH. Effect
of a multifaceted, church-based wellness program on metabolic syndrome in 41
overweight or obese congregants.Prev Chronic Dis. Jul;7(4):A81-A88,
Weaver KL, Ivester P, Seeds M, Case LD, Arm JP, Chilton
FH. Effect of dietary fatty acids on inflammatory gene
expression in healthy humans. J Biol Chem. 5: 284(23):
Peachman KK, Bowton DL, Sivertson K, and Chilton
FH. Regulation of arachidonate remodeling enzymes impacts eosinophil survival
during allergic asthma. Am. J. Respir. Cell Mol. Biol.41(3):358-66,
Weaver KL, Ivester P, Chilton JA, Wilson MD, Pandey
P, Chilton FH. The content of favorable and unfavorable
polyunsaturated fatty acids found in commonly eaten fish. J Am Diet Assoc. 2008
Chilton FH, Rudel LL, Parks JS, Arm JP, Seeds MC.
Mechanisms by which botanical lipids affect inflammatory disorders. Am J Clin
Nutr. 2008 Feb; 87(2):498S-503S.