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Floyd “Ski” Chilton, PhD

Floyd “Ski” Chilton, PhD - Recent Publications

Books:


The Rewired Brain, Baker Books, 2016
Made to Crave Action Plan
Zondervan/ Harper Collins, 2011
The Gene Smart Diet
, Rodale, 2009
Win the War Within, Rodale, 2006
Inflammation Nation, Simon and Schuster, 2005


Chosen from over 135 peer reviewed publications: 

Sergeant S, Ruczinski I, Ivester P, Lee TC, Morgan T, Nicklas BJ, Mathias RA, Chilton FH. Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. Brit J Nutr. 115(2):251-61, 2016.

Miller LR, Jorgensen MJ, Kaplan JR, Seeds MC,  Rahbar E, Morgan TM,  Welborn  A, Chilton SM, Gillis J, Hester A, Rukstalis M, and Sergeant S,  Chilton FH. Alterations in levels and ratios of n-3 and n-6 polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys from birth to early adulthood. Physiol Behav 156:71-78, 2016.

Sergeant S, Rahbar E, and Chilton FH. Gamma-linolenic acid, Dihommo-gamma linolenic acid, Eicosanoids and Inflammatory Processes. Eur J  Pharmacol 785:77-86, 2016.

Cui T, Hester AG, Seeds MC, Rahbar E, Howard TD, Sergeant S, Chilton FH. Impact of Genetic and Epigenetic Variations Within the FADS Cluster on the Composition and Metabolism of Polyunsaturated Fatty Acids in Prostate Cancer. Prostate 76(13):1182-91, 2016. 

MathiasRA, SeedsMC, Pani V, Sergeant S, ChiltonFH. Genetic variants in the FADS gene:  implications for dietary recommendations for fatty acid intake. Curr Nutr Rep Jun;3(2):139-148, 2014.

Chilton FH, Murphy RC, Wilson BA, Sergeant S, Ainsworth H, Seeds MC and Mathias RA. Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases. Nutrients. 6(5):1993-2022, 2014.

Howard TD, Mathias RA, Seeds MC, Herrington DM, Hixson JE, Shimmin LC, Hawkins GA, Sellers M, Ainsworth HC, Sergeant S, Miller LR, and Chilton FH. DNA methylation in an enhancer region of the FADS Cluster is associated with FADS activity in human liver. PLoS ONE. May19; 9(5):e97510. doi: 10.1371/journal. pone. 0097510, 2014.

Hester GA, Murphy, RC, Uhlson CJ, Ivester P, Lee TC, Sergeant S, Miller LR, Howard TD, Mathias RA, Chilton, FH. Relationship between Common Variants in the Fatty Acid Desaturase (FADS) Cluster and Eicosanoid Generation in Humans. J Biol Chem, Jun 24. pii: jbc.M114.579557, 2014.

Kazani S, Arm J, Boyce J, Chhay H, Dutile S, Wechsler M, Govindarajulu U, Ivester P, Ainsworth H, Sergeant S, Chilton F and Israel E. LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma. Springerplus. 2014 3:661, 2014. 

Lee TC, Ivester P, Sergeant S, Ainsworth H, Case DL, Morgan T, Bowden DW,  Chilton FH. The impact of polyunsaturated fatty acid-based dietary supplements on disease biomarkers in a metabolic syndrome/diabetes population. Lipids Health Dis. 13(1):196, 2014.

Kavanagh K, Flynn DM, Jenkins KA, Wilson MD, Chilton FH. Stearidonic and gamma-linolenic acids in echium oil improves glucose disposal in insulin resistant monkeys. Prostaglandins Leukot Essent Fatty Acids. 89(1):39-45, 2013.

Arm JP, Wang L, Chhay H, Zahid M, Patil V, Govindarajulu U, Ivester P, Weaver KL, Israel E, Chilton FH. Impact of a botanical oil combination (Echium plantagineum and Borago officinalis) on leukotriene generation and pulmonary function in asthmatics subjects. Lipids Health Dis. 12:141. doi: 10.1186/1476-511X-12-141, 2013.

Sergeant S,Hugenschmidt CE, Rudock ME, Ziegler JT, Ivester P, ­­­Ainsworth, HC, Vaidya D, Case LD, Langefeld CD, Freedman BI, Bowden DW, Mathias RA, ChiltonFH. Differences in arachidonic acid levels and fatty acid desaturase (FADS) in African Americans and European Americans with diabetes/metabolic syndrome. Brit J Nutr 107:547, 2012.

Mathias RA, Fu W, Akey JM, Ainsworth HC, Torgerson DJ, Ruczinski I, Sergeant S, Barnes KC, Chilton FH. Adaptive evolution of the FADS gene cluster within Africa. PLoS ONE Sept 19; 7(9): e44926, 2012.

Mathias RA, Hugenschmidt CE, Sergeant S, Torgerson DG, Ziegler JT, Ivester P, Case LD, Yanek LR, Bowden DW, Freedman BI, Rudock ME, Becker LC, Langefeld CD, Becker DM, Barnes KC, Chilton FH. The impact of FADS genetic variants on omega-6 polyunsaturated fatty acid metabolism in African Americans.BMC Genetics. May 20; 12(1):50, 2011.

Sergeant S, McQuail JE, Riddle D, Chilton FH, Ortmeier S, Jessup JA, Groban L, Nicolle MM. Dietary fish oil attenuates diastolic dysfunction, but has no effect on memory or brain measures of inflammation in aged rats. J Gerontology: Biol Sci.May;66(5):521-33, 2011.

Chilton FH, Lee TC, Willard SL, Ivester P, Sergeant S, Register TC, Shively SA. Depression and altered serum lipids in cynomolgus monkeys on a Western diet.Physiol Behav.104: 222-27, 2011.

Mathias RA, Vergara C, Gao L, Rafaels N, Hand T, Campbell M, Bickel C, Ivester P, Sergeant S, Barnes  KC, Chilton FH. Association of fatty acid desaturase (FADS) gene cluster genetic variants with omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population. J Lipid Res. Sept;51(9):2766-74, 2010.

Ivester P, Sergeant S, Danhauer SC, Case LD, Lamb A, Chilton BG, Delar B, Hollingshead ML, Weaver KL, Chilton FH. Effect of a multifaceted, church-based wellness program on metabolic syndrome in 41 overweight or obese congregants.Prev Chronic Dis. Jul;7(4):A81-A88, 2010.

Weaver KL, Ivester P, Seeds M, Case LD, Arm JP, Chilton FH.  Effect of dietary fatty acids on inflammatory gene expression in healthy humans.  J Biol Chem. 5: 284(23): 15400-7, 2009.

Seeds MC, Peachman KK, Bowton  DL, Sivertson K, and Chilton FH. Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma. Am. J. Respir. Cell Mol. Biol.41(3):358-66, 2009.

Weaver KL, Ivester P, Chilton JA, Wilson MD, Pandey P, Chilton FH. The content of favorable and unfavorable polyunsaturated fatty acids found in commonly eaten fish. J Am Diet Assoc. 2008 Jul;108:1178-85.

Chilton FH, Rudel LL, Parks JS, Arm JP, Seeds MC. Mechanisms by which botanical lipids affect inflammatory disorders. Am J Clin Nutr. 2008 Feb; 87(2):498S-503S.   

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