J. Charles Eldridge, PhD

J. Charles Eldridge, PhD - Stress and Aging

Stress and Aging

Presentations and Publications  

Landfield PW, Sundberg DK, Smith MS, Eldridge JC, Morris M. Neural and endocrine changes in mid- and late-life in rats: Possible implications for mechanisms of aging. Peptides 1 (Suppl 1):185-196 (1980)  

Eldridge JC, Lymangrover JR. Prolactin stimulates and potentiates adrenal steroid secretion in vitro. Federation of American Societies for Experimental Biology, 66th Annual Meeting, New Orleans, LA, 1982; Fed Proc 41:1243 (1982)  

Lymangrover JR, Keku E, Eldridge JC. Naloxone potentiates ACTH- and angiotensin II- but not potassium-stimulated aldosterone secretion in vitro. Life Sci 33:1605-1612 (1983)  

Eldridge JC, Lymangrover JR. Prolactin stimulates and potentiates adrenal steroid secretion in vitro. Hormone Res 20:252-260 (1984)  

Eldridge JC, Lymangrover JR. Sexual divergence of aging effects on rat adrenocortical steroid output in vitro. The Endocrine Society, 68th Annual Meeting, Anaheim, CA, 1986. p. 233  

Sonntag WE, Goliszek AG, Eldridge JC. Diminished diurnal secretion of ACTH but not corticosterone in old male rats. The Endocrine Society, 68th Annual Meeting, Anaheim, 1986, p. 234  

Eldridge JC, Fleenor DG, Kerr DS, Campbell LW, Landfield PW. Age-related changes in density and up-regulation of types I and II hippocampal corticosteroid receptors. Society for Neuroscience, 17th Annual Meeting, New Orleans, LA, 1987; Soc Neurosci Abstr 13:436 (1987)   

MacLean DB, Eldridge JC, Brodish A. Evidence of ACTH-adrenal and stress-induced down-regulation of substance P in the sensory vagus nerve. In: JL Henry, R Couture, AC Cuello, G Pelletier, G Quirion, R Segoli (eds), Substance P and Neurokinins, Springer-Verlag, New York, 1987, pp. 260-262  

Sonntag WE, Goliszek AG, Brodish A, Eldridge JC. Diminished diurnal secretion of ACTH but not corticosterone in old male rats: Possible relation to increased adrenal sensitivity to ACTH in vivo. Endocrinology 120:2308-2315 (1987)  

O'Steen WK, Sweatt AJ, Eldridge JC, Brodish A. Gender and chronic stress effects on the neural retina of aging Fischer-344 rats. Neurobiol Aging 8:449-455 (1987)  

MacLean DB, Eldridge JC, Brodish A. Substance P and somatostatin content and transport in the vagus and sciatic nerves of aging Fischer-344 rats. Neurobiol Aging 9:273-277 (1987)  

Eldridge JC, Fleenor DG, Kerr DS, Landfield PW. Impaired up-regulation of type II corticosteroid receptors in hippocampus of aged rats. Brain Research 478:248-256 (1989)  

Eldridge JC, Brodish A, Kute TE, Landfield PW. Apparent age-related resistance of type II hippocampal corticosteroid receptors to down-regulation during chronic escape training.  J Neurosci 9:3237-3242 (1989)  

Landfield PW, Eldridge JC. Increased affinity of type II corticosteroid binding in aged rat hippocampus. Exper Neurol 106:110-113 (1989)  

Landfield PW, Fleenor DG, Eldridge JC, McEwen BS. Effects of aging on 3H-nimodipine binding in rat brain. Society for Neuroscience, 19th Annual Meeting, Phoenix, AZ, 1989; Soc Neurosci Abs 15:80 (1989)  

Landfield PW, Booze RM, Vinsant S, Cadwallader LB, Eldridge JC. Glucocorticoid receptor immuno-staining is increased in aging hippocampus. Society for Neuroscience, 20th Annual Meeting, St. Louis, MO, 1990; Soc Neurosci Abs 16:31 (1990)  

Landfield PW, Eldridge JC. The Glucocorticoid Hypothesis of Brain Aging: New Findings on Cellular Mechanisms. Symposium: Aging,Second International Congress of Neuroendocrinology, Bordeaux, France, 1990  

Eldridge JC, Landfield, PW, Booze RM. Corticosteroid Receptors, Aging and Alzheimer's Disease. Symposium: Aging and the Hypothalamic-Pituitary-Adrenocortical System,International Symposium on Animals, Hormones, Aging and Cancer, Utrecht, Netherlands, 1991   

Landfield PW, Eldridge JC. The glucocorticoid hypothesis of brain aging and neurodegeneration:  Recent modifications. Acta Endocrinol 125, Suppl 1:54-64 (1991)  

Blizard DA, Jones BC, Eldridge JC. Differences in prolactin but not HPA response to stress in Maudsley reactive and non-reactive rats. First International Behavioral Neuroscience Conference, San Antonio, TX, 1992, p. 36  

Landfield PW, Eldridge JC. Glucocorticoid Hypothesis of Age-related Hippocampal Degeneration: New Developments and Mechanisms. Symposium: Brain Corticosteroid Receptors: Studies on the Mechanism, Function and Neurotoxicity of Corticosteroid Action, New York Academy of Sciences Conference, Arlington, VA, 1994  

Eldridge JC, Wetzel LT, Tisdel MO, Stevens JT. Pattern of reproductive aging in female rats can affect mammary tumor incidence. Symposium: 2nd International Symposium on Hormonal Carcinogenesis, Stockholm, Sweden, 1994  

Eldridge JC, Wetzel LT, Tisdel MO, Stevens JT. Pattern of reproductive aging in female rats can affect mammary tumor incidence. III European Congress of Endocrinology, Amsterdam, Netherlands, 1994; Eur J Endocrinol 130 (Suppl 2):112 (1994)  

Landfield PW, Eldridge JC. Evolving aspects of the glucocorticoid hypothesis of brain aging: hormonal modulation of neuronal calcium homeostasis. Neurobiol Aging 15:579-588 (1994)  

Landfield PW, Eldridge JC. The glucocorticoid hypothesis of age-related hippocampal neurodegeneration: Role of dysregulated intraneuronal calcium. Ann NY Acad Sci 746:308-326 (1995)  

Eldridge JC, Wetzel LT, Tisdel MO. Patterns of reproductive aging in female rats can affect mammary tumor incidence. In: Li JJ, Li SA, Gustafsson J‑A, Nandi S, Sekely LI (eds), Hormonal Carcinogenesis II, Springer‑Verlag, Inc., New York, NY, 1996, pp. 467‑470  

Eldridge JC. Mechanisms Underlying Mammary Tumor Development in Aging Female Rats. Symposium on Reproductive Biology and Hormone Action: in Honor of Virendra B. Mahesh, Ph.D., D. Phil., Medical College of Georgia, Augusta, GA, 1998  

Simpkins JW, Eldridge JC, Wetzel LT.  Role of strain-specific reproductive patterns in the appearance of mammary tumors in atrazine-treated rats.  In: Ballantine LG, McFarland JE, Hackett DS (eds), Triazine Herbicides: Risk Assessment, Oxford University Press, Washington, DC, 1998, pp. 399-413  

Eldridge JC. Stress Theory of Aging. In: Maddox GL, Atchley RC,  Evans JG, Hudson RB, Kane RA, Masoro EJ, Mexy MD, Poon LW, Siegler IC (eds)  Encyclopedia of Aging (3rd edition), Springer Publishing Co., New York NY, 2000, pp. 1161-1163

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