Kenneth Kishida, PhD
Kenneth Kishida, PhD
Dept. of Physiology & Pharmacology
Dept. of Neurosurgery
Wake Forest School of Medicine
Medical Center Boulevard
Winston-Salem, North Carolina 27157-1083
Baylor College of Medicine, PhD, Neuroscience (2006)
University of California at Davis, BS, Genetics (1999)
Human cognition, decision-making, computational psychiatry, dopamine, serotonin, human neuroimaging (fMRI, MEG, invasive electrochemistry and electrophysiology), human voltammetry, translational neuroscience
Brief Summary of Research
My research is focused on discovering basic neurobiological
mechanisms that support human cognition and human decision-making.
These basic questions guide the work in my
(1) How does activity in the human brain give rise to human
experience, human beliefs, and human choice behavior?
(2) How does the environment and social interaction modulate these
(3) How can we use answers to these questions to improve the quality
of life of all humans, but especially those that suffer from neurological and
In human decision-making, conscious and
subconscious processes are clearly at play. However, how these dichotomous
depictions of human cognition interact and guide human decision-making via
concrete neurobiological mechanisms remains poorly understood.
My laboratory uses intracranial measures (e.g.,
human voltammetry, stereo-EEG, and micro-electrode recordings) as well as
noninvasive neuroimaging tools (e.g., fMRI and MEG) to measure brain activity
during conscious decision-making in humans. We use behavioral tasks that are
constrained by computational considerations borrowing ideas from game theory
and machine learning. In combining these disciplines, we investigate how the
human brain navigates constrained decision-spaces to discover neural process
that are involved in real-time human decision-making.
We further extend our work in the human brain
with the use of model organisms and in
vitro experimentation to develop new tools for use in human neuroscience and to investigate basic neurobiological
processes that are motivated by our discoveries in the human brain.