Mei-Chuan Ko, PhD

Mei-Chuan Ko, PhD - Selected Publications

Published articles in PubMed

Rizzi A, Sukhtankar DD, Ding H, Hayashida K, Ruzza C, Guerrini R, Calo’ G, Ko MC. (2015)
Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys. British Journal of Pharmacology 172(14):3661-3670.  

Lee H, Ko MC. (2015)
Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates. Scientific Reports 5:11676.  

Ding H, Hayashida K, Suto T, Sukhtankar DD, Kimura M, Mendenhall V, Ko MC. (2015)
Supraspinal actions of nociception/orphanin FA, morphine and substance P in regulating pain and itch in non-human primates. British Journal of Pharmacology 172(13):3302-3312.  

Schröder W. Lambert DG. Ko MC. Koch T. (2014)
Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists. British Journal of Pharmacology 171(16):3777-3800.  

Sukhtankar DD. Lee H. Rice KC. Ko MC. (2014)
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. Psychopharmacology (Berl) 231(7):1377-1387.  

Molinari S. Camarda V. Rizzi A. Marzola G. Salvadori S. Marzola E. Molinari P. McDonald J. Ko MC. Lambert DG. Calo’ G. Guerrini R. (2013)
[Dmt1]N/OFQ(1-13)-NH2, a potent nociceptin/orphanin FQ and opioid receptor universal agonist. British Journal of Pharmacology 168(1):151-162.  

Sukhtankar DD. Ko MC. (2013)
Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice. PLoS ONE 8(6):e67422.  

Sukhtankar DD. Zaveri NT. Husbands SM. Ko MC. (2013)
Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/m-opioid receptor ligands in mouse models of neuropathic and inflammatory pain. Journal of Pharmacology and Experimental Therapeutics 346(1):11-22.  

Lin AP. Ko MC. (2013)
The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability. ACS Chemical Neuroscience 4(2):214-224.  

Ko MC. Husbands SM. (2013)
Research and Development of Opioid-Related Ligands (Editors: MC Ko & SM Husbands). ACS Symposium Series, volume 1131, American Chemical Society/ACS Publications, Washington DC, USA (Distributed in print by Oxford University Press, Inc.). ISBN13: 978-0841227828.  

Cremeans CM. Gruley E. Kyle DJ. Ko MC. (2012)
Roles of m-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in monkeys. Journal of Pharmacology and Experimental Therapeutics 343(1):72-81.  

Su PY. Ko MC. (2011)
The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats. Journal of Pharmacology and Experimental Therapeutics 337(3):822-829.  

Collins GT. Carey KA. Narasimhan D. Nichols J. Berlin AA. Lukacs NW. Sunahara RK. Woods JH. Ko MC. (2011)
Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology 36(5):1047-1059.  

Hu E. Calo’ G. Guerrini R. Ko MC. (2010)
Long lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112. Pain 148(1):107-113.


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