Michael A. Nader, PhD

Michael A. Nader, PhD - Past Students and Post-Docs


Past Students

 

 R_GouldRobert W, Gould, PhD
[October, 2011]


“Cocaine self-administration in rhesus monkeys: effects on neurobiology and cognition and evaluation of cognitive enhancement for cocaine addiction”. 

Awards: David K. Sundberg award; ASPET Washington Fellow

Current position: Post-doctoral Fellow, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center, Nashville, TN

Publications while in the lab:
Gould RW, Garg PK, Garg S, Nader MA. Effects of nicotine acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history. Neuropharmacology 2013; 64: 479-488.

Gould RW, Gage HD, Nader MA. Effects of chronic cocaine self-administration on cognition and cerebral glucose utilization in rhesus monkeys. Biol Psychiatry 2012; 72: 856-863.

Nader MA, Nader SH, Czoty PW, Riddick NV, Gage HD, Gould RW, Blaylock BL, Kaplan JR, Garg PK, Davies HML, Morton D, Garg S, Reboussin BA. Social dominance in female monkeys: dopamine receptor function and cocaine reinforcement. Biol Psychiatry 2012; 72: 414-421.

Gould RW, Porrino LJ, Nader MA. Nonhuman primate models of addiction and PET imaging: Dopamine system dysregulation. In CS Carter, JW Dalley (eds), “Brain Imaging in Behavioral Neuroscience”, Springer-Verlag, Heidelberg, Germany. Curr Topics in Behav Neurosci 2012; 11: 25-44.

Blaylock BL, Gould RW, Banala A, Grundt P, Luedtke RR, Newman AH, Nader MA. Influence of cocaine history on the behavioral effects of dopamine D3 receptor-selective compounds in monkeys. Neuropsychopharmacology 2011; 36: 1104-1113.

Czoty PW, Gould RW, Martelle JL, Nader MA. Prolonged attenuation of the reinforcing strength of cocaine by chronic d-amphetamine in rhesus monkeys. Neuropsychopharmacology 2011 36: 539-547.

Gould RW, Czoty PW, Nader SH, Nader MA. Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. J Pharmacol Exp Ther 2011; 339: 678-686.

Gould RW, Gage HD, Banks ML, Blaylock BL, Czoty PW, Nader MA. Differential effects of cocaine and MDMA self-administration on cortical serotonin transporter availability in monkeys. Neuropharmacology 2011; 61: 245-251.

Nader MA, Czoty PW, Gould RW, Riddick NV. Characterizing organism x environment interactions in nonhuman primate models of addiction: PET imaging studies of dopamine D2 receptors. In: T Robbins, B Everritt, DJ Nutt (eds), “The Neurobiology of Drug Addiction: New Vistas”, Oxford University Press, Oxford, UK, 2010: 187-202.

Czoty PW, Gould RW, Nader MA. Relationship between social rank and cortisol and testosterone concentrations in male cynomolgus monkeys (Macaca fascicularis). J Neuroendocrinol 2009; 21: 68-76.

Banks ML, Gould RW, Czoty PW, Nader MA. Relationship between response rates and measures of reinforcing strength using a choice procedure in monkeys. Behav Pharmacol 2008; 19: 365-369.

Nader MA, Czoty PW, Gould RW, Riddick NV. PET imaging studies of dopamine receptors in primate models of addiction. Phil Trans Royal Soc B 2008; 363: 3223-3232.

Sikoski P, Banks ML, Gould R, Young RW, Wallace JM, Nader MA. Comparison of rectal and infrared thermometry for obtaining body temperature in cynomolgus macaques (Macaca fascicularis). J Med Primatol, 2007 36: 381-384.

Nader MA, Czoty PW, Nader SH, Calhoun T, Sandridge J, Gould R, Icenhower M, Riddick N, Bounds MC, Gage HD. Brain imaging and monkey models of cocaine abuse. In: Di Chiara G, Carbon E, Valentini V, Aquas E, Bassareo V, Cadoni C, eds, “Monitoring Molecules in Neuroscience: Proceeding of the 11th International Conference on In Vivo Methods”. University of Cagliari, Cagliari, Italy, 2006, pp. 60-62.


 
 L_HamiltonLindsey R. Hamilton, PhD
[June, 2010]


“Neurobiological and behavioral phenotypes and cocaine self-administration in adult rhesus monkeys exposed to cocaine throughout gestation”.

Awards: NRSA predoctoral award

Current position: Post-doctoral Fellow, Neurobehavioral Toxicology Branch, United States Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD

Publications while in the lab:
Hamilton LR, Czoty PW, Gage HD, Nader MA. Characterization of the dopamine receptor system in adult rhesus monkeys exposed to cocaine throughout gestation. Psychopharmacology 2010; 210: 481-488.

Hamilton LR, Czoty PW, Nader MA. Behavioral characterization of adult male and female rhesus monkeys exposed to cocaine throughout gestation. Psychopharmacology 2011; 213: 799-808.
 

 
 
natalliaNatallia V. Riddick, PhD
[November, 2008]

“Factors that affect social hierarchy and the influence of social rank and menstrual cycle on cocaine self-administration in female cynomolgus monkeys.”

Current position
: Research Specialist, Mouse Behavioral Phenotyping Laboratory, Department of Psychiatry, University of North Carolina, Chapel Hill, NC

Publications while in the lab
:
Nader MA, Nader SH, Czoty PW, Riddick NV, Gage HD, Gould RW, Blaylock BL, Kaplan JR, Garg PK, Davies HML, Morton D, Garg S, Reboussin BA. Social dominance in female monkeys: dopamine receptor function and cocaine reinforcement. Biol Psychiatry 2012; 72: 414-421.

Nader MA, Czoty PW, Gould RW, Riddick NV. Characterizing organism x environment interactions in nonhuman primate models of addiction: PET imaging studies of dopamine D2 receptors. In: T Robbins, B Everritt, DJ Nutt (eds), “The Neurobiology of Drug Addiction: New Vistas”, Oxford University Press, Oxford, UK, 2010: 187-202

Czoty PW, Riddick NV, Gage HD, Sandridge JM, Nader SH, Garg S, Bounds M, Garg PK, Nader MA. Effect of menstrual cycle phase on dopamine D2 receptor availability in female cynomolgus monkeys. Neuropsychopharmacology 2009; 34: 548-554.

Riddick NV, Czoty PW, Gage HD, Kaplan JR, Nader SH, Icenhower M, Pierre PJ, Bennett A, Garg PK, Nader MA. Behavioral and neurobiological characteristics influencing social hierarchy formation in female cynomolgus monkeys. Neuroscience 2009; 158: 1257-1265.

Nader MA, Czoty PW, Gould RW, Riddick NV. PET imaging studies of dopamine receptors in primate models of addiction. Phil Trans Royal Soc B 2008; 363: 3223-3232.

Nader MA, Czoty PW, Nader SH, Calhoun T, Sandridge J, Gould R, Icenhower M, Riddick N, Bounds MC, Gage HD. Brain imaging and monkey models of cocaine abuse. In: Di Chiara G, Carbon E, Valentini V, Aquas E, Bassareo V, Cadoni C, eds, “Monitoring Molecules in Neuroscience: Proceeding of the 11th International Conference on In Vivo Methods”. University of Cagliari, Cagliari, Italy, 2006, pp. 60-62.
 

jenniferJennifer L. Martelle, MD, PhD [PhD, May 2008; MD, May 2010]

“An evaluation of the behavioral and pharmacological determinants of the discriminative stimulus and reinforcing effects of cocaine using a within-subjects design in rhesus monkeys”.


Awards: 
NRSA predoctoral award; Gordon Melson Outstanding Dissertation, 2008; David K. Sundberg Award

Current Position: Resident Physician in Pediatrics, University of California at San Francisco

Publications while in the lab:
Martelle JL, Nader MA. Animal models of drug addiction: Cocaine. In P Miller (Ed) “The Encyclopedia of Addictive Behaviors”, Chapter 38, Elsevier Inc, San Diego, CA, in press.

Czoty PW, Gould RW, Martelle JL, Nader MA. Prolonged attenuation of the reinforcing strength of cocaine by chronic d-amphetamine in rhesus monkeys. Neuropsychopharmacology 2011 36: 539-547.

Czoty PW, Martelle JL, Carroll FI, Nader MA. Lower reinforcing strength of the cocaine analogs RTI-336 and RTI-177 compared to cocaine in nonhuman primates. Pharmacol Biochem Behav 2010; 96: 274-278.

Czoty PW, Martelle JL, Nader MA. Effects of chronic d-amphetamine administration on the reinforcing strength of cocaine in rhesus monkeys. Psychopharmacology 2010; 209: 375-382.

Martelle JL, Nader MA. A within-subject assessment of the discriminative stimulus and reinforcing effects of self-administered cocaine in rhesus monkeys. Psychopharmacology 2009; 203: 343-353.

Martelle JL, Czoty PW, Nader MA. Effect of time-out duration on the reinforcing strength of cocaine assessed under a progressive-ratio schedule in rhesus monkeys. Behav Pharmacol 2008; 19: 743-746.

Martelle JL, Nader MA. A review of the discovery, pharmacological characterization, and behavioral effects of the dopamine D2-like receptor antagonist eticlopride. CNS Neurosci Ther 2008; 14: 248-262.

Martelle JL, Claytor R, Ross JT, Newman AH, Nader MA. Effects of two novel D3-selective compounds, NGB 2904 and CJB 090, on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. J Pharmacol Exp Ther 2007; 321: 573-582.

Czoty PW, Martelle JL, Nader MA. Influence of abstinence and conditions of cocaine access on the reinforcing strength of cocaine in nonhuman primates. Drug Alcohol Dep 2006; 85: 213-220. 


matthewMatthew L. Banks, PharmD, PhD
[May, 2007]


“Role of thermoregulation in MDMA pharmacology: Implications for abuse”.

Awards: 
NRSA predoctoral fellowship; David K. Sundberg Award

Current Position: Assistant Professor of Toxicology and Pharmacology at VCU

Publications while in the lab:
Banks ML, Czoty PW, Sprague JE, Nader MA. Influence of ambient temperature on a primate model of MDMA (Ecstasy) abuse. In: Di Chiara G, Carbon E, Valentini V, Aquas E, Bassareo V, Cadoni C, eds, “Monitoring Molecules in Neuroscience: Proceeding of the 11th International Conference on In Vivo Methods”. University of Cagliari, Cagliari, Italy, 2006, pp. 398-400.

Banks ML, Czoty PW, Nader MA. The influence of reinforcing effects of cocaine on cocaine-induced increases in extinguished responding. Psychopharmacology 2007; 192: 449-456.

Banks ML, Sprague JE, Kisor DF, Czoty PW, Nichols DE, Nader MA. Ambient temperature effects on 3,4-methylenedioxymethamphetamine (MDMA)-induced thermodysregulation and pharmacokinetics in male monkeys. Drug Disposition Metab 2007; 35: 1840-1845.

Sikoski P, Banks ML, Gould R, Young RW, Wallace JM, Nader MA. Comparison of rectal and infrared thermometry for obtaining body temperature in cynomolgus macaques (Macaca fascicularis). J Med Primatol, 2007 36: 381-384.

Banks ML, Czoty PW, Gage HD, Bounds MC, Garg PK, Garg S, Nader MA. Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys. Neuropsychopharmacology 2008; 33: 219-225.

Banks ML, Czoty PW, Sprague JE, Nader MA. Influence of thyroid hormones on 3,4-methylenedioxymethamphetamine-induced thermogenesis and reinforcing strength in monkeys. Behav Pharmacol 2008; 19: 167-170.

Banks ML, Gould RW, Czoty PW, Nader MA. Relationship between response rates and measures of reinforcing strength using a choice procedure in monkeys. Behav Pharmacol 2008; 19: 365-369.

Banks ML, Sprague JE, Czoty PW, Nader MA. Effects of ambient temperature on the relative reinforcing strength of MDMA using a choice procedure in monkeys. Psychopharmacology 2008; 196: 63-70.

renee

D. Renee Claytor, PhD
[December, 2005]

“The effects of dopamine receptor antagonists and partial agonists on food- and cocaine-maintained responding in rhesus monkeys”.


Current position:
US Patent Office, Washington, DC

Publications while in the lab:
Claytor R, Lile JA, Nader MA. The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacol Biochem Behav 2006; 83: 456-464.

Martelle JL, Claytor R, Ross JT, Newman AH, Nader MA. Effects of two novel D3-selective compounds, NGB 2904 and CJB 090, on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. J Pharmacol Exp Ther 2007; 321: 573-582.

jasonJason Ross, MS
[May, 2004]

“Assessment of the abuse liability of (1S, 2R, 3S, 5S)-2-Etoymethyl-3-(3,4-dichloro-phenyl)-8-methyl-azabicyclo [3.2.1] octane citrate (NS2330) in rhesus monkeys”.


Publications while in the lab:

Lile JA, Ross JT, Nader MA. A comparison of the reinforcing efficacy of 3,4-methylenedioxymethamphetamine (MDMA, “ecstatsy”) with commonly abused psychostimulants in rhesus monkeys. Drug Alcohol Dep 2005; 78: 135-140.

Martelle JL, Claytor R, Ross JT, Newman AH, Nader MA. Effects of two novel D3-selective compounds, NGB 2904 and CJB 090, on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. J Pharmacol Exp Ther 2007; 321: 573-582.

joshua

Joshua A. Lile, PhD
[December, 2002]

“An analysis of the pharmacological variables that determine the reinforcing efficacy of drugs acting at central monoamine systems.”


Awards: 
NRSA predoctoral fellowship

Current position: Associate Professor of Behavioral Sciences, University of Kentucky School of Medicine

Publications while in the lab:
Lile J, Morgan D, Freedland CS, Sinnott RS, Davies HML, Nader MA. Self-administration of two long-acting monoamine transport blockers in rhesus monkeys. Psychopharmacology 2000; 152: 414-421.

Lile J, Morgan D, Nader MA. Single- vs. multiple-session substitution: an evaluation of the reinforcing effects of cocaine and the cocaine analog 2ß-propanoyl-3ß-(4-tolyl)-tropane (PTT). Exp Clin Psychopharmacol 2000; 8: 424-433.

Lile JA, Morgan D, Birmingham AM, Wang Z, Woolverton WL, Davies HM, Nader MA. The reinforcing efficacy of the dopamine reuptake inhibitor PTT as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys. J Pharmacol Exp Ther 2002; 303: 640-648.

Lile JA, Nader MA. The abuse liability and therapeutic potential of drugs evaluated for cocaine addiction as predicted by animal models. Curr Neuropharmacol 2003; 1: 21-46.

Lile JA, Wang Z, Woolverton WL, France JE, Gregg TC, Davies HML, Nader MA. The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics. J Pharmacol Exp Ther 2003; 307: 356-366.

Lile JA, Morgan D, Birmingham AM, Davies HML, Nader MA. Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food-and cocaine-maintained responding in rhesus monkeys. Psychopharmacology 2004; 174: 246-253.

Lile JA, Ross JT, Nader MA. A comparison of the reinforcing efficacy of 3,4-methylenedioxymethamphetamine (MDMA, “ecstatsy”) with commonly abused psychostimulants in rhesus monkeys. Drug Alcohol Dep 2005; 78: 135-140.

Claytor R, Lile JA, Nader MA. The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacol Biochem Behav 2006; 83: 456-464.


rachna

Rachna Sinnott, PhD
[December, 1999]

“An analysis of dopamine receptor subtype modulation of cocaine’s behavioral effects in rhesus monkeys.”


Current position:
Director of Foundation & Corporate Relations, Whitman College, Walla Walla, WA

Publications while in the lab:
Sinnott RS, Mach RH, Nader MA. Dopamine D2/D3 receptors modulate cocaine’s reinforcing and discriminative stimulus effects in rhesus monkeys. Drug Alcohol Dep 1999; 54: 97-110.

Lile J, Morgan D, Freedland CS, Sinnott RS, Davies HML, Nader MA. Self-administration of two long-acting monoamine transport blockers in rhesus monkeys. Psychopharmacology 2000; 152: 414-421.

Sinnott RS, Nader MA. Modulation of cocaine’s discriminative stimulus effects by dopamine D1 agonists in rhesus monkeys. Pharmacol Biochem Behav 2001; 68: 301-309.

Nader MA, Sinnott RS, Mach RH, Morgan D. Cocaine- and food-maintained responding under a multiple schedule in rhesus monkeys: environmental context and the effects of a dopamine antagonist. Psychopharmacology 2002; 163: 292-301.

Past Post-doctoral fellows

  
drakeDrake Morgan, PhD
[1999-2001]


Current position: Assistant Professor of Psychiatry, University of Florida

Publications while in the lab:
Lile J, Morgan D, Freedland CS, Sinnott RS, Davies HML, Nader MA. Self-administration of two long-acting monoamine transport blockers in rhesus monkeys. Psychopharmacology 2000; 152: 414-421.

Lile J, Morgan D, Nader MA. Single- vs. multiple-session substitution: an evaluation of the reinforcing effects of cocaine and the cocaine analog 2ß-propanoyl-3ß-(4-tolyl)-tropane (PTT). Exp Clin Psychopharmacol 2000; 8: 424-433.

Morgan D, Grant KA, Prioleau OA, Nader SH, Kaplan JR, Nader MA. Predictors of social status in cynomolgus monkeys (macaca fascicularis) after group formation. Am J Primatol, 2000; 52: 115-131.

Morgan D, Nader MA. Acquisition of intravenous cocaine self-administration with concurrent access to food in cynomolgus monkeys. Exp Clin Psychopharmacol 2000; 8: 554-565.

Nader MA, Morgan D. Influence of group social behavior on cocaine's effects in cynomolgus monkeys. In: Harris LS, ed,  "Problems of Drug Dependence 2000, Proceedings of the 62nd Annual Meeting”. NIDA Research Monograph 181, U.S. Government Printing Office, Washington, D.C., 2001: 51-52.

Nader MA, Morgan D. Effects of negative punishment contingencies on cocaine self-administration by rhesus monkeys. Behav Pharmacol 2001; 12: 91-99.

Lile JA, Morgan D, Birmingham AM, Wang Z, Woolverton WL, Davies HM, Nader MA. The reinforcing efficacy of the dopamine reuptake inhibitor PTT as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys. J Pharmacol Exp Ther 2002; 303: 640-648.

Morgan D, Grant KA, Gage HD, Mach RH, Kaplan JR, Prioleau O, Nader SH, Buchheimer N, Ehrenkaufer RL, Nader MA. Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nature Neuroscience 2002; 5: 169-174.

Nader MA, Gage HD, Mach RH, Morgan D. The use of PET imaging to examine the effects of cocaine and socially derived stress on dopamine D2 receptors in nonhuman primates. In: Harris LS, ed,  "Problems of Drug Dependence 2001, Proceedings of the 63rd Annual Meeting”. NIDA Research Monograph 182, U.S. Government Printing Office, Washington, D.C., 2002: 55-57

Nader MA, Sinnott RS, Mach RH, Morgan D. Cocaine- and food-maintained responding under a multiple schedule in rhesus monkeys: environmental context and the effects of a dopamine antagonist. Psychopharmacology 2002; 163: 292-301.

Czoty PW, Morgan D, Shannon EA, Gage HD, Nader MA. Characterization of dopamine D1 receptor function in socially housed cynomolgus monkeys. Psychopharmacology 2004; 174: 381-388.

Lile JA, Morgan D, Birmingham AM, Davies HML, Nader MA. Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food-and cocaine-maintained responding in rhesus monkeys. Psychopharmacology 2004; 174: 246-253.

Nader MA, Morgan D, Gage HD, Nader SH, Calhoun T, Buchheimer N, Ehrenkaufer R, Mach RH. PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys. Nature Neurosci 2006; 9: 1050-1056.


ciara2Ciara McCabe, PhD
[2003-2004]

 


Current position:
Department of Experimental Psychology, University of Oxford

Publications while in the lab:
Czoty PW, McCabe C, Nader MA. Assessment of the reinforcing strength of cocaine in socially housed monkeys using a choice procedure. J Pharmacol Exp Ther 2005; 312: 96-102.

Czoty PW, McCabe C, Nader MA. Effects of the 5-HT1A agonist (±)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on cocaine choice in cynomolgus. Behav Pharmacol 2005; 16:187-191.

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