Translational Studies on Early-Life Stress and Vulnerability to Alcohol is an NIH-funded Program Project (P01) grant that provides the research environment and infrastructure needed to promote translational alcohol research at this institution.  The overarching research focus of this collaborative project is to employ human, non-human primate, and rodent models to investigate the neurobiological mechanisms that link environmental and behavioral factors like early-life stress, anxiety, and PTSD to an increased risk of alcohol abuse.  This P01 grant offers a wide range of training and educational opportunities in translational alcohol research and currently supports the following three projects:

Project 1 (Dr. Paul Laurienti, PI): Functional Brain Networks and Alcohol Composition: Associations with Age, Stress, and Cognition

Project 2 (Drs. David Friedman and Paul Czoty, co-PIs): Translational Model Development for Non-Human Primate Studies of Risk Factors Linking Anxiety-Like Behaviors and Alcohol Consumption

Project 3 (Drs. Sara Jones, Brian McCool and Jeff Weiner, Co-PIs): A Rodent Model of Early Life-Stress Increases Behavioral Risk Factors of Comorbid Anxiety Disorders and Alcoholism

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