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Selected Recent Publications


Watson NL, Sutton-Tyrrell K, Youk AO, Boudreau RM, Mackey RH, Simonsick EM, Rosano C, Hardy SE, Windham BG, Harris TB, Najjar SS, Lakatta EG, Atkinson HH, Johnson KC, Bauer DC, Newman AB for the Health ABC Study.  Arterial stiffness and gait speed in older adults with and without peripheral arterial disease.  Am J Hypertens 2011;24:90-95.  PMCID:  PMC3290653

Watson NL, Sutton-Tyrrell K, Rosano C, Boudreau RM, Hardy SE, Simonsick EM, Najjar SS, Launer LJ, Yaffe K, Atkinson HH, Satterfield S, Newman AB.  Arterial stiffness and cognitive decline in well-functioning older adults.  J Gerontol A Biol Sci Med.  2011;66:1336-1342. PMCID: PMC3210954 

Schwartz AV, Margolis KL, Sellmeyer DE, Vittinghoff E, Ambrosius WT, Bonds DE, Josse RG, Schnal AM, Simmons DL, Hue TF, Palermo L, Hamilton BP, Green JB, Atkinson HH, O'Conner PJ, Force RW,  Bauer DC.  Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial.  Diabetes Care 2012;35:1525-1531.  PMCID:  PMC3379596

BAKER, Laura

Craft S, Baker LD, Montine TJ, Minoshima S, Watson GS, Claxton A, Arbuckle M, Callaghan M, Tsai E, Plymate SR, Green PS, Leverenz J, Cross D, Gerton B. Intranasal insulin therapy for Alzheimer's disease and mild cognitive impairment. Arch Neurol. 2012;69(1)29-38. 

Baker LD, Carter JL, Skinner J, Montine TJ, Green PS, Callaghan M, Leverenz J, Walter BK, Tsai E, Postupna N, Zhang J, Lampe J, Craft S. High-intensity physical activity modulates diet effects on cerebrospinal β-amyloid levels in normal aging and mild cognitive impairment. J Alzheimers Dis. 2012;28(1):137-46. 

Baker LD, Asthana S, Cholerton BA, Wilkinson CW, Plymate SR, Green PS, Fishel MA, Watson GS, Cherrier MM, Mehta PD, Merriam GR, Craft S. Cognitive response to estradiol in postmenopausal women is modified by high cortisol. Neurobiol Aging,   2012;33(4);829.e9-e20. 

Cholerton B, Baker LD, Trittschuh EH, Crane PK, Larson EB, Arbuckle M, Hernandez H, McCurry SM, Bowen JD, McCormick WC, Craft C. Insulin and sex interactions in older adults with mild cognitive impairment.   J Alzhiemer's Dis.   in press. 

Baker LD, Borson S, Barsness SM, Merriam GR, Friedman SD, Craft S, Vitiello MV. Growth hormone-releasing hormone improves cognitive function in mild cognitive impairment and healthy aging: results of a controlled trial. Arch Neurol, 2012; Aug 6:1-10. doi: 10.1001/archneurol.2012.1970. [Epub ahead of print]

CRAFT, Suzanne

Carter, J.L., Green, P.S., Montine, T.J., Van Fossen, B., Baker, L.D., Watson, G.S., Bonner, L.M., Callaghan, M., Leverenz, J., Walter, B.K., Tsai, E., Plymate, S.R., Postupna, N., Wilkinson, C.W., Zhang, J., Lampe, J., Kahn, S.E., Craft, SDiet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment. Arch Neurol, 68:743-752, 2011. 

Craft, S., Baker, L.D. Montine, T.J., Minoshima, S., Watson, G.S., Claxton, A., Arbuckle, M., Callaghan, M., Tsai, E., Plymate, S.R., Green, P.S., Leverenz, J., Cross, D., Gerton, B.  Intranasal insulin therapy for AD and MCI: A pilot clinical trial.  Archives of Neurology, 69:29-38, 2012. PMC3260944 doi: 10.1001/archneurol.2011.233 

DELBONO, Osvaldo  

Birbrair A *, Zhang T *, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O. Skeletal Muscle Neural Progenitor Cells Share Markers with NG2-Glia and Derive from Pericytes. Experimental Cell Research. 2013 Jan 1;319(1):45-63. doi: 10.1016/j.yexcr.2012.09.008. Epub 2012 Sep 20. 

Birbrair A *, Zhang T *, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O. Skeletal Muscle Pericyte Subtypes Differ in their Differentiation Potential. Stem Cell Research. 2012 Sep 29;10(1):67-84. doi: 10.1016/j.scr.2012.09.003. [Epub ahead of print]. 

Yasuda T, Delbono O, Wang ZM, Messi ML, Girard T, Urwyler A, Treves S, Zorzato F. JP-45/JSRP1 variants affect skeletal muscle excitation contraction coupling by decreasing the sensitivity of the dihydropyridine receptor. Hum Mutat. 2012 Aug 24. doi: 10.1002/humu.22209. [Epub ahead of print] 

Choi, S.J., Shively,C.A., Register, T. C., Stehle, J.,  High, K., Ip, E., Feng, X., Kritchevsky, S. B., Nicklas, B., and Delbono, O. Force Generation Capacity of Single Muscle Fibers of Vastus Lateralis Declines with Age and Correlates with Physical Function in African Green Vervet Monkeys. Journal of Gerontology. Biological Sciences. J Gerontol A Biol Sci Med Sci. 2012 Aug 24. [Epub ahead of print] 

Files, D.C. *, D'Alessio, F. R., Johnston, L. F., Kesari, P., Aggarwal, N. R., Garibaldi, B. T., Mock, J. R., Simmers, J. L., DeGorordo, A., Murdoch, J., Willis, M. S., Patterson, C., Tanskersley, C.G., Messi, M. L., Liu, L., Delbono, O., Furlow, J. D., Bodine, S. C., Cohn, R. D., King, L. S., and Crow, M. T.  A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-Associated Skeletal Muscle Wasting. American Journal of Respiratory and Critical Care Medicine. 2012 Feb 3. [Epub ahead of print]. 

Delbono, O., Messi, M. L., Wang, Z-M., Treves, S., Mosca, B., Bergamelli, L., Nishi, M., Takeshima, H., Shi, H*, Xue, B, and Zorzato, F. Endogenously determined restriction of food intake overcomes excitation-contraction uncoupling in JP45KO mice with aging. Experimental Gerontology. 2012 Jan 25. [Epub ahead of print] 

Wang ZM, Tang S, Messi ML, Yang JJ, Delbono OResidual sarcoplasmic reticulum Ca2+ concentration after Ca2+ release in skeletal myofibers from young adult and old mice. Pflugers Arch. 2012 Jan 17. [Epub ahead of print]. PMID: 22249494. PMC Journal - In Process 

LYLES, Mary  

Shea MK, Nicklas BJ, Lyles MF, Carr JJ, Miller ME, Miller GD, Marsh AP, Harris TB, Kritchevsky SB.  The effect of pioglitazone and resistance training on body composition in older men and women undergoing weight loss. Obesity, 2011 Aug;19(8):1636-46. doi: 10.1038/oby.2010.327. Epub 2011 Jan 13., 2011. PMID: 21233810 PMCID: PMC3091968 

Beavers KM, Lyles MF, Davis CC, Wang X, Nicklas BJ.  Is lost lean mass from intentional weight loss recovered during weight regain in postmenopausal women?    2011 Sep;94(3):767-74. Epub 2011 Jul 27.  Am J Clin Nutr. 2011 Sep;94(3):767-74.  PMID:21795437  PMCID: PMC3155932 

Walker FO, Lyles MF, Li Z. Sheet fitting palsy. J Clin Neuromuscul Dis. 2012 Sep;14(1):48-50. PMID: 22922583  

HOUSTON, Denise  

Leishear K, Boudreau RM, Studenski SA, Ferrucci L, Rosano C, de Rekeneire N, Houston DK, Kritchevsky SB, Schwartz AV, Tylavsky FA, Vinik AI, Hogervorst E, Yaffe K, Harris TB, Newman AB, Strotmeyer ES. The Relationship of Vitamin B12 and Sensory and Motor Peripheral Nerve Function. J Am Geriatr Soc, 2012; 60:1057-63. 

Shahar DR, Houston DK, Hue TF, Lee JS, Sahyoun NR, Tylavsky FA, Geva D, Vardi H, Harris TB. Adherence to Mediterranean Diet and Decline in Walking Speed over 8 Years in Community-Dwelling Older Adults. J Am Geriatr Soc, 2012; 60:1881-8. 

Kritchevsky SB, Tooze JA, Neiberg RH, Schwartz GG, Hausman DB, Johnson MA, Bauer DC, Cauley JA, Shea MK, Cawthon PM, Harris TB, Rubin SM, Tylavsky FA, Houston DK. 25-Hydroxyvitamin D, Parathyroid Hormone and Mortality in Black and White Older Adults: the Health ABC Study. J Clin Endocrinol Metab, 2012 2012; 97:4156-65. 

Levin GP, Robinson-Cohen C, de Boer IH, Houston DK*, Lohman K, Liu Y, Kritchevsky SB, Cauley JA, Tanaka T, Ferrucci L, Bandinelli S, Patel KV, Hagström E, Michaëlsson K, Melhus H, Wang T, Wolf M, Psaty BM, Siscovick D, Kestenbaum B. Genetic Variants and Associations of 25-hydroxyvitamin D Concentrations with Major Clinical Outcomes. JAMA, 2012; 308:1898-1905 (*lead investigator for Health ABC) 

Houston DK, Tooze JA, Neiberg RH, Hausman DB, Johnson MA, Cauley JA, Bauer DC, Cawthon PM, Shea MK, Schwartz GG, Williamson JD, Tylavsky FA, Visser M, Simonsick EM, Harris TB, Kritchevsky SB. 25-Hydroxyvitamin D Status and Change in Physical Performance and Strength in Older Adults: the Health, Aging, and Body Composition Study. Am J Epidemiol, 2012; 176:1025-34 [doi: 10.1093/aje/kws147]. 

Houston DK, Neiberg RH,   Tooze JA,   Hausman DB, Johnson MA, Cauley JA, Bauer DC, Shea MK, Schwartz GG, Williamson JD, Harris TB, Kritchevsky SB. Low 25-Hydroxyvitamin D Predicts the Onset of Mobility Limitation and Disability in Community-Dwelling Older Adults: the Health ABC Study. J Gerontol: Med Sci, 2012 [Epub ahead of print; doi: 10.1093/gerona/gls136]. 

Beavers KM, Hsu FC, Houston DK,   Beavers DP, Harris TB, Hue TF, Kim LJ, Koster A, Penninx BW, Simonsick EM, Strotmeyer ES, Kritchevsky SB, Nicklas BJ. The Role of Metabolic Syndrome, Adiposity, and Inflammation in Physical Performance in the Health ABC Study. J Gerontol: Med Sci, 2012 [Epub ahead of print; doi:10.1093/gerona/gls213].  

KRITCHEVSKY, Stephen    

Kritchevsky SB, Tooze JA, Neiberg RH, Schwartz GG, Hausman DB, Johnson MA, Bauer DC, Cauley JA, Shea MK, Cawthon PM, Harris TB, Rubin SM, Tylavsky FA, Houston DK. 25-Hydroxyvitamin D, Parathyroid Hormone, and Mortality in Black and  White Older Adults: The Health ABC Study. J Clin Endocrinol Metab. 2012 Aug 31.[Epub ahead of print] PubMed PMID: 22942386. 

Leishear K, Boudreau RM, Studenski SA, Ferrucci L, Rosano C, de Rekeneire N, Houston DK, Kritchevsky SB, Schwartz AV, Vinik AI, Hogervorst E, Yaffe K, Harris  TB, Newman AB, Strotmeyer ES; Health, Aging and Body Composition Study. Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults. J Am Geriatr Soc. 2012 Jun;60(6):1057-63. PubMed PMID: 22690982; PubMed Central PMCID:PMC3376015. 

Choi SJ, Shively CA, Register TC, Feng X, Stehle J, High K, Ip E, Kritchevsky SB, Nicklas B, Delbono O. Force-Generation Capacity of Single Vastus Lateralis Muscle Fibers and Physical Function Decline With Age in African Green Vervet Monkeys. J Gerontol A Biol Sci Med Sci. 2012 Aug 24. [Epub ahead of print] PubMed PMID: 22923428. 

Feng X, Xu Z, Butler SG, Leng I, Zhang T, Kritchevsky SB. Effects of aging and levodopa on the laryngeal adductor reflex in rats. Exp Gerontol. 2012 Jul 21. [Epub ahead of print] PubMed PMID: 22824541. 

Kavanagh K, Wylie AT, Chavanne TJ, Jorgensen MJ, Voruganti VS, Comuzzie AG, Kaplan JR, McCall CE, Kritchevsky SB. Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance. J Gerontol A Biol Sci Med Sci. 2012 Oct;67(10):1014-21. Epub 2012 Mar 8. PubMed PMID: 22403054; PubMed Central PMCID:PMC3437965. 

Cawthon PM, Fox KM, Gandra SR, Delmonico MJ, Chiou CF, Anthony MS, Caserotti P, Kritchevsky SB, Newman AB, Goodpaster BH, Satterfield S, Cummings SR, Harris TB; Health, Aging and Body Composition Study. Clustering of strength, physical function, muscle, and adiposity characteristics and risk of disability in older adults. J Am Geriatr Soc. 2011 May;59(5):781-7. PubMed PMID: 21568948; PubMed Central PMCID: PMC3196375 

MOLINA, Anthony 

Twig, G., Liu, X., Liesa, M., Wikstrom, J. D., Molina, A. J., Las, G., Yaniv, G., Hajnoczky, G. & Shirihai, O. S.  (2010). Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity. Am.J.Physiol Cell   Physiol, 299, C477-C487. PMC2928626

Trudeau, K., Molina, AJ., Guo, W. & Roy, S.  (2010). High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy. Am.J.Pathol., 177, 447-455. PMC2893686

Trudeau, K., Molina, AJ., Roy, S.  (2011). High Glucose Induces Mitochondrial Morphology and Metabolic Changes in Retinal Pericytes. Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8657-64 

Gall, JM., Wang, Z., Liesa, M., Molina, AJ., Havasi, A., Schwartz, JH., Shirihai, O., Borkan, SC., Bonegio, RG. (2012). Role of mitofusin 2 in the renal stress response. PLoS One. 7(1):e31074. Epub 2012 Jan 26. 

Wheeler, AL., Molina, AJ., Shirihai, OS. (2012) A faster, high resolution, mtPAGFP-based mitochondrial fusion assay acquiring kinetic data of multiple cells in parallel using confocal microscopy. JOVE (Accepted for Publication)  

NICKLAS, Barbara

Wang X, Hsu FC, Isom S, Walkup MP, Kritchevsky SB, Goodpaster BH, Church TS, Pahor M, Stafford R, Nicklas BJEffects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women.  J Gerontol A Biol Sci Med Sci, 67(4):417-24, 2012. PMC3309873 

Nicklas BJ, Gaukstern JE, Legault C, Leng X, Rejeski WJ.  Intervening on spontaneous physical activity to prevent weight regain in older adults: design of a randomized clinical trial.  Comtemp Clin Trials, 33(2):450-5, 2012. PMID: 22155331 PMC3318982 

Marsh AP, Rejeski WJ, Espeland MA, Miller ME, Church TS, Fielding RA, Gill TM, Guralnik JM, Newman AB, Pahor M; LIFE Study Investigators, Muscle strength and BMI as predictors of major mobility disability in the Lifestyle Interventions and Independence for Elders pilot (LIFE-P).  J Gerontol A Biol Sci Med Sci, 66(12):1376-83, 2011. PMID: 21975090 PMC3210962 

Cesari M, Kritchevsky SB, Nicklas BJ, Kanaya AM, Patrignani P, Tacconelli S, Tranan GJ, Tognoni G, Harris TB, Incalzi RA, Newman AB, Pahor M; for the Health ABC study.  Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons:  results from the Health Aging and Body Composition study.  J Gerontol A Biol Sci Med Sci, 67A(6):671-676, 2012. PMID: 22389462 PMC3348494 

Stehle JR, Leng X, Kitzman DW, Nicklas BJ, Kritchevsky SB, High KP.  LPS binding protein (LBP), a surrogate marker of microbial translocation associated with physical function in healthy older adults.    J Gerontol A Biol Sci Med Sci, (In Press), 2012.

Brinkley TE, Hsu FC, Beavers KM, Church TS, Goodpaster BH, Stafford RS, Pahor M, Kritchevsky SB, Nicklas BJTotal and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach.  J Gerontol A Biol Sci Med Sci, 67(10):1099-1106, 2012. PMID: 22451470 PMC3437966 

Beavers KM, Miller ME, Rejeski WJ, Nicklas BJ, Kritchevsky SB.  Fat mass loss predicts gain in physical function with intentional weight loss in older adults.  J Gerontol A Biol Sci Med Sci. Epub, 2012. PMID: 22503993 

Beavers KM, Beavers, DP, Houston DK, Harris TB, Hue TF, Koster A, Newman AB, Simonsick EM, Studenski SA, Nicklas BJ, Kritchevsky SB.  Associations between body composition and gait speed decline: results from the Health ABC Study.  Am J Clin Nutr, (In Press), 2012.

SINK, Kaycee

Bettermann K,  Arnold AM, Williamson J, Rapp S,  Sink KM, Toole J, Carlson MC, Yasar S, DeKosky S, Burke GL.  Statins, Risk of   Dementia and Cognitive Function: Secondary Analysis of the Ginkgo Evaluation of Memory Study (GEMS). J of Stroke and Cerebrovascular Diseases. 2012 Aug;21(6):436-44  PMID:21236699; PMCID:PMC3140577 

Chapman B, Duberstein P, Tindle HA, Sink KM, Robbins J, Tancredi DJ, Franks P for the Gingko Evaluation of Memory (GEM) Study Investigators.  Personality Predicts Cognitive Function Over Seven Years in Older Persons. Am J of Geriatric Psychiatry. 17 August 2012 Jul;20(7):612-21. PMID:22735597. PMCID:PMC3384996. 

Yasar S, Lin F, Fried LP, Kawas CH, Sink, KM, DeKosky ST, Carlson MC for the Ginkgo Evaluation of Memory (GEM) Study Investigators. Diuretic Use is Associated with Better Learning and Memory in Older Adults in the GEM Study. Journal of Alzheimer's and Dementia. 2012 May;8(3):188-95. PMID:22465175.  PMCID:PMC3341535. 

Legault C, Jennings JM, Katula JA, Dagenbach D, Gaussoin SA, Sink KM, Rapp SR, Rejeski WJ, Shumaker SA, Espeland MA.  Designing Clinical Trials for Assessing the Effects of Cognitive Training and Physical Activity Interventions on Cognitive Outcomes: The Seniors Health and Activity Research Program Pilot (SHARP-P) Study, a Randomized Controlled Trial.   BMC Geriatrics.   2011 May 26; 11(1):27 PMID:21615936. PMCID:PMC3126708. 

Buettner LL, Fitzsimmons S, Atav S, Sink KCognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's.  J Aging Res. 2011 April 28; 2011 PMID:21584241. PMCID:PMC3092580. 

Divers J, Hugenschmidt C, Sink KM, Williamson JD, Ge Y, Smith SC, Bowden DW, Whitlow CT, Maldjian JA, Freedman BI.  Cerebral White Matter Hyperintensity in African Americans and European Americans with Type 2 Diabetes.  J of Stroke and Cerebrovascular Diseases  2012 May 16. [Epub ahead of print].  PMID:22608346. PMCID: PMC3465633


Butler SG, Stuart A, Leng X, Wilhelm E, Rees C, Williamson J, Kritchevsky SB. The relationship of aspiration status with tongue and handgrip strength in healthy older adults. J Gerontol A Biol Sci Med Sci. 2011; 66(4):452-458.

Inzitari M, Arnold AM, Patel KV, Mercer LD, Karlamangla A, Ding J, Psaty BM, Williamson JD, Kuller LH, Newman AB.  Subclinical vascular disease burden and risk for death and cardiovascular events in older community dwellers. J Gerontol A Biol Sci Med Sci. 2011;66(9):986-93.  PMCID:  PMC3202905

Murray AM, Barzilay JI, Lovato JF, Williamson JD, Miller ME, Marcovina S, Launer LJ, for the Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes (MIND-ACCORD) Substudy Investigators. Biomarkers of renal function and cognitive impairment in patients with diabetes. Diabetes Care. 2011;34(8):1827-32. PMCID:  PMC3142061 

Launer LJ, Miller ME, Williamson JD, Lazar RM, Gerstein HC, Murray AM, et al. for the ACCORD MIND Investigators. Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open label substudy. Lancet Neurol.  2011;10(11);969-977. PMCID: PMC3333485

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Ellis LR, Levitan D, Pardee TS, Isom S, Powell BL. The feasibility of inpatient geriatric assessment for older adults receiving induction chemotherapy for acute myelogenous leukemia. J Am Geriatr Soc. 2011;59(10):1837-1846.


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