Current Projects

Hayashida Lab Projects

Hayashida Figure1

Figure 1. Nerve injury increases extracellular glutamate by down-regulation of GLT-1, and this inhibits evoked glutamate release by enhanced presynaptic inhibition. The increased glutamate concentration results in increased tonic LC activity that impairs PFC-related cognitive function, and the reduced evoked glutamate release diminishes noradrenergic response important to descending inhibition of pain.


Quick Reference

Pain Mechanisms Lab

Dr. James Eisenach

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Hayashida Lab Publications

A concise list of publications by Kenichiro Hayashida, DVM, PhD, Assistant Professor, Anesthesiology specializing in pain research. 

Last Updated: 01-05-2016
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