Current Projects

Martin Lab Projects

Martin Project
Under grant NS074357 from the National Institute of Neurodegenerative Disorders and Stroke we are studying the effects of deep brain stimulation in rats with neuropathic pain. Deep brain stimulation has recently received renewed interest as a treatment modality for a number of CNS disorders including chronic, intractable pain. We are interested in finding brain regions in which electrical stimulation reverses classical symptoms of nerve-injury associated pain in rats, such as mechanical hypersensitivity. Additionally, using operant conditioning procedures we are interested in finding brain regions that are uniquely reinforcing in the presence of chronic neuropathic pain. Our goal is to find brain regions that merit investigation in humans for relief of chronic intractable pain, as well as merit further study for supraspinal mechanisms of analgesia in laboratory animals.



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Pain Mechanisms Lab

Dr. James Eisenach
336-716-4182

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Martin Lab Publications

A concise list of publications by Thomas J. Martin, PhD, Associate Professor, specializing in pain research. 

Last Updated: 09-29-2014
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