7T MRI Facility

The 7T Facility is located on the basement level of the Nutrition Research Building. This facility houses a Bruker Biospin 7T microMRI scanner.

 

John Olson, MS is the Coordinator of the Small Animal Imaging Facility. MR techniques currently available on this scanner include:

• In vivo mouse, rat, and non-human primate imaging with sub 0.1mm resolution 
• Magnetically labeled cell tracking 
• Mouse and rat cardiac and atherosclerosis imaging 
• Proton Spectroscopy 
• Diffusion Tensor Imaging

7T Bruker microMR Scanner

Superconducting Magnet System 

• Actively-shielded superconducting wide-bore magnet 
• Nitrogen free (no cryogenic maintenance by customer) 
• Cryo-refrigerator (Minimal helium consumption, long hold-times, long maintenance intervals) 
• Reduced stray field 
• Screening against external field perturbations 
• Table attached to the magnet front side with integrated rail for animal handling system 
• Field strength: 7 T 
• Diameter of clear bore: > 300 mm 
• Stray-field (5 Gauss): +/- 3 m axial, +/- 2 m radial 
• Length: 1.45 m 
• Diameter: 1.655 m 
• Passive RT shim system 
• Vibration damping (absorber)

Gradient system B-GA 20S with RT-shim and related power supplies 

• Actively shielded gradients 
• Integrated shim set up to 2nd order 
• Outer / inner diameter: 301.5 mm / 200.5 mm 
• Gradient amplitude: 200 mT/m 
• Max. slew rate: 1100 T/m/s 
• Linearity 130 / 100 mm DSV: < ± 3%, < ± 2% 
• Water cooled

Gradient system BGA12-S with RT-shim and related power supplies

• Actively shielded gradients 
• Integrated shim set 1st & 2nd order 
• Outer/inner diameter 206mm / 116 mm 
• Gradient amplitude 660 mT/m 
• Max slew rate: 4570 T/m/s 
• Linearity/DSV (+/- %/mm) 3/130 
• Water cooled

Gradient system BGA6-S

• Actively shielded gradients 
• Integrated shim set; up to 2nd order 
• Outer / inner diameter: 113mm / 60mm 
• Gradient amplitude: 1000 mT/m 
• Max. slew rate: 11250 T/m/s 
• Linearity/DSV (+/- %/mm) 5/35 
• Water cooled 
• User Interface: Linux Workstation 
• ParaVision4.0 
• Topspin1.5 
• Jive6.0

RF Coils 

• Volume coils 
• Litzcage RF Volume coils 
• 25 mm (mice), 38 mm (live rat brains), 50 mm (rat brains) 
• Bruker 72 mm volume coil (rats up to 600 grams) 
• Bruker 150 mm volume coil (non-human primate brains) 
• Surface coils 
• 25 mm (Tx/Rx), 35 mm (Rx only)

Anesthesia/Monitoring 

• Surgivet anesthesia machine - Isoflurane and oxygen 
• SA Instruments animal monitoring 
• ECG monitoring, respiratory monitoring, temperature monitoring 
• Animal warmer – temperature maintained with thermostatically controlled warm air