Co-Faculty
Rebecca Alexander, PhD Reynolda Campus-Chemistry Department Research in our laboratory centers on mechanisms of bacterial protein synthesis, using protein engineering, kinetic studies, and in vitro selection schemes. Faculty Page Laboratory Page
K.C. Balaji, MD Urology Dr. Balaji's research efforts over a decade has focused on identifying novel signaling mechanisms contributing to prostate cancer development and progression. Faculty Page Laboratory Page
Arthur W. Blackstock Jr., MD Radiation Oncology Faculty Page Laboratory Page
Ulrich Bierbach, PhD Reynolda Campus-Chemistry Department Research in our laboratory is concerned with the design of small-molecule agents for the cure and management of life-threatening diseases and for probing and modulating gene regulation. Laboratory Page
David L. Carroll, PhD Physics My primary research interests are: growth, assembly, and characterization of novel nanostructures, nano-photonics and the quantum-functional properties of nanophase blends, organic nanocomposite devices including organic photovoltaics, lighting systems, and IR sensors, biomedical-nanotechnology including nano-enabled hyperthermia based approaches to cancer treatment, advanced/responsive tissue scaffolding technology, and biology-technology signal transduction. Faculty Page Laboratory Page
Waldemar Debinski, MD, PhD Microbiology/Immunology & Neurosurgery The main goal of my laboratory is to advance research in the areas of unmet needs in medicine; a majority of primary brain tumors represents such needs. Our focus is on the identification of molecular markers/targets that are specific to brain tumors. Faculty Page Laboratory Page
Purnima Dubey, PhD Pathology My lab is interested in mechanisms of tumor progression. We study the role of the protein Prostate Stem Cell Antigen in cancer metastasis. We also investigate the adaptive immune system in prostate cancer progression, and utilize non-invasive imaging techniques to follow the localization and function of T lymphocytes at the tumor site. Faculty Page Laboratory Page
Patricia Gallagher, PhD Hypertension & Vascular Research Center Research in the Tallant/Gallagher laboratory focuses on the cellular and molecular regulation of the renin-angiotensin system (RAS). Faculty Page Laboratory Page
Martin Guthold, PhD Reynolda Campus-Physics Department My research interests are in the general areas of Biophysics, Molecular Biology and nanotechnology. Faculty Page
Paul Jones, PhD Reynolda Campus-Chemistry Department I am interested in studying how photochemistry is used in nature and in developing photochemical methods to generate synthetically and medically significant products. Laboratory Page
S. Bruce King, PhD Reynolda Campus-Chemistry Department Our research program is based on a combination of organic chemistry and biochemistry directed towards understanding the various roles nitric oxide (NO) performs in biological systems. Laboratory Page
Greg Kucera, PhD Hematology/Oncology The general aim of my research is to influence the potential for clinical trials through laboratory investigations of novel anticancer drugs or combinations of anticancer drugs that affect cellular proliferation through signaling pathways. Faculty Page Laboratory Page
Frank C. Marini, PhD Institute for Regenerative Medicine Faculty Page Laboratory Page
Linda Metheny-Barlow, PhD Radiation Oncology My laboratory studies angiogenesis and cell-cell interactions in the tumor microenvironment. Our goal is to identify strategies both to inhibit tumor angiogenesis as well as normalize the tumor vasculature to enhance the effectiveness of current therapeutic strategies. Faculty Page Laboratory Page
Akiva Mintz, MD, PhD Neurosurgery Therefore, a focus of laboratory is to deliver both diagnostic and therapeutic molecular radiotherapy to brain tumor biomarkers that are not expressed on normal brain tissue. Faculty Page Laboratory Page
Aaron Mohs, MD Institute for Regenerative Medicine Faculty Page Laboratory Page
David Ornelles, PhD Microbiology & Immunology My research concerns the oncogenes of adenovirus that circumvent host cell restrictions to virus replication. Our research addresses the rational design of replicating, oncolytic viruses for cancer therapy and a possible role for adenovirus in the etiology of childhood leukemia. Faculty Page Laboratory Page
Timothy S. Pardee, MD, PhD Hematology/Oncology My lab is focused on developing a better understanding of Acute Myeloid Leukemia (AML). This cancer is characterized by a high relapse rate and resistance to chemotherapy. To address these issues we utilize several mouse models of AML that incorporate genetic changes found in the human disease. Faculty Page Laboratory Page
W. Jeff Petty, MD Hematology/Oncology My research focuses on two distinct but convergent signaling pathways: the epidermal growth factor receptor (EGFR) pathway and the retinoic acid receptor (RAR) pathway. By understanding mechanisms of response or resistance to drugs that target these pathways, I hope to develop effective chemoprevention strategies that could be used to treat early stages lung carcinogenesis. Faculty Page
Freddie Salsbury, PhD. Reynolda Campus Physics Department My research is focused on computational molecular biophysics; broadly construed. Faculty Page
Shay Soker, PhD Regenerative Medicine In my research I am investigating the role of VEGF and its receptors in neovascularization, vascular diseases and in cancer. Faculty Page Laboratory Page
Ann Tallant, PhD Hypertension & Vascular Research Center Research in the Tallant/Gallagher laboratory focuses on the cellular and molecular regulation of the renin-angiotensin system (RAS). Faculty Page Laboratory Page
Alan Townsend, PhD Biochemistry Exposure of cells to reactive electrophilic agents can damage cellular protein and lipid structures, and can cause genetic changes leading to abnormal growth control and cancer. We are interested in the enzymatic mechanisms for activation vs. detoxification of carcinogenic mutagens. Faculty Page Laboratory Page
Yuh-Hwa Wang, PhD Biochemistry Human fragile sites in cancer; Trinucleotide repeat expansion diseases; Chromatin structure; Unusual DNA sequence and structure. Laboratory Page
Mark Welker, PhD Reynolda Campus-Chemistry Department One of my lab’s long term research goals is to produce nontoxic cancer chemopreventive agents. A comprehensive cancer treatment strategy will ultimately involve the use of small molecules for both the treatment and prevention of cancer. Laboratory Page
Patricia Wilson, PhD Institute for Regenerative Medicine Dr. Wilson is broadly interested in understanding how stem cells maintain their stem cell identity and yet respond to intrensic and extrinsic cues to initiate differentiation into specialized cell types. Faculty Page Laboratory Page
Siqun Lilly Zheng, MD Pulmonary & Critical Care Department My group focuses on genetic changes in prostate cancer. Faculty Page
Jianfeng Xu, MD, PhD Human Genomics My group focuses on prostate cancer gene mapping using various approaches such as genetic linkage studies, family-based and population-based association studies, and molecular positional cloning technique. Faculty Page