About the Center for Cancer Genomics
In 2008 the Center for Cancer Genomics was established at Wake Forest University Health Sciences in Winston-Salem, North Carolina. This new center evolved out of the Program for Genetic and Molecular Epidemiology of Cancer.
In the past 14 years, we have made contributions to the field of cancer genetics using high-throughput genotyping and sequencing, and genetic epidemiologic tools. We have published more than 250 peer-reviewed papers in cancer genetics, including those in the New England Journal of Medicine, Nature Genetics, and Journal of the National Cancer Institute. We have also received more than 35 extramural research grants funded through the National Institutes of Health and the Department of Defense.
Our mission is to use genomics approaches to gain an understanding of the complex processes involved in the development and progression of various types of cancer, and to develop approaches to utilize this information for the prediction of cancer and personalized intervention.
To accomplish our mission, we have assembled a team of researchers, clinicians and staff from diverse backgrounds with expertise in epidemiology, genetics, molecular biology, statistics, nutrition, and computer science.
- Identify germline and somatic genetic and epigenetic alterations that are associated with the development and progression of cancer
- Understand the interaction of genetic and epigenetic alterations in cancer development and progression
- Develop approaches to utilize genetic and epigenetic information for prediction and early detection of cancer (personalized risk prediction)
- Pharmacogenetics (personalized intervention)
- Foster collaboration with other researchers to understand the functional mechanisms by which genetic and epigenetic findings have a direct effect on cancer