Genomics Seminars

The Center for Genomics and Personalized Medicine Research seminars will be held on Wednesdays from 4-5 PM in the Genomics Conference Room,  G-floor, Nutrition Building.  

Speakers will primarily be junior faculty, post-docs and colleagues, though anyone affiliated with the Center is welcome to volunteer.  Occasionally, outside speakers will be invited to present. 

The format will be an approximately 50 minute research presentation, as a way to share research progress and common genomic analysis techniques.  Seminars are primarily being organized by Jielin Sun and Xingnan Li, with the assistance of faculty and administrative staff.  

Please contact Jielin or Xingnan by email (jisun@wakehealth.edu or xinli@wakehealth.edu) if you are interested in volunteering to present or if you know of anyone else who may be interested in presenting or attending.  

All Center for Genomics and Personalized Medicine Research members will be encouraged to attend. 

Light refreshments will be provided.   

 September 2011

14- Jeremy Stuart, PhD, MPH, Applied Biosystems 
          "Trends in Next-Generation Sequencing:  Applications & Implications for Translational Research"

21- Junjie Feng, PhD, Center for Cancer Genomics
          "Genetic Variants in the Androgen Receptor Cistrome and Prostate Cancer"

27- Nora Franceshini, MD, University of North Carolina at Chapel Hill
          "Genetics of Blood Pressure in Minorities"

October

5- Nicholette Allred, PhD, Genomics/ Diabetes Research Center 
          "A Genome Wide Association Search for Type 2 Diabetes Genes in African Americans"

19- Rebecca Slager, PhD, Genomics and Personalized Medicine Research
          "Genetic and Pharmacogenetic Analysis of the TH2 Pathway in Asthma"

26- Timothy L. Lash, D.Sc., MPH, Division of Public Health Sciences, Department of Epidemiology and Prevention
          "Tamoxifen pharmacogenetics: Review, Results and Future Directions"

November

2- Donata Vercelli, MD, University of Arizona
          "Genetic and Epigenetic Determinants of Susceptibility to Allergic Inflammation"

9- Anthony Molina, PhD, Department of Internal Medicine, Section on Gerontology and Geriatric Medicine
            "The Mitochondrial Quality Control Axis: Implications in Diabetes, Obesity and Aging"

16- Wendy Moore, MD, Pulmonary/ Genomics and Personalized Medicine Research 
          "Phenotyping Strategies in Complex Diseases: Using Cluster Analysis to Identify Novel Multidimensional Phenotypes of Asthma"

30- Michael Knowles, MD, UNC School of Medicine
            "Gene modifiers of CF Lung Disease: Update on Mechanistic Insights"

December

7- Jin Woo Kim, PhD, Center for Cancer Genomics
          "DNA Methylation Profiling in Prostate Cancer Using a New Illumina 450 BeadArray"

14- Lindsay Reynolds, Public Health Sciences 
           "Analysis of Risk Factors for Periodontal Diseases"

February

1- Nicholas Pajewski, PhD, Department of Biostatistical Sciences, Division of Public Health Sciences 
            "Host Genetics and Personalized Vaccinology: Application to Biodefense and Anthrax"

15- Michael Wu, UNC School of Medicine 
             "Statistical Methods for Analysis of Rare Variants in Sequencing Studies"

29- Shyh-huei Chen, PhD, Department of Biostatistical Sciences, Division of Public Health Sciences
              "Using Graded Response Model for the Predictionj of Prostate Cancer Risk"

 

March

21- Seh-Hoon Oh, PhD, Wake Forest Institute for Regenerative Medicine
              "Characterization of a Novel Functional Protein in the Pancreatic Islet"

April

4- LaChelle Waller, Genomics and Personalized Medicine Research

18- Erwin Bottinger, MD,  Mt. Sinai School of Medicine
25- Mark Miller, Cancer Biology

 

 PAST SEMINARS 

 January 2010 

 6- Floyd "Ski" Chilton, Physiology/ Pharmocology
        "Impact of the varying frequencies at common genetic variants in the FADS gene cluster on circulating levels of inflammatory fatty acids in African-Americans and Caucasians"  

 12- Naftali Kaminski, MD, University of Pittsburgh
       "Role of microRNas in lung fibrosis"

13- Carl Langefeld, PHS Biostatistics
       "Searching for genetic variants and environmental interactions"

20- Christina Hugenschmidt, Genomics/ Diabetes Research Center
       "Integrating MR imaging variable in genetic association analyses"

27- Isaac Lipkus, Duke Cancer Center
   
February   

 3- Peter Antinozzi, Genomics/ Diabetes Research Center
       "Functional mapping of diabetes-susceptibility loci:  Leveraging high-throughput genotyping with high-content cell based assays"  

 10- Lance Miller, Cancer Biology
        "Microarrays, gene signatures, and the road to clinical translation"  

 17- Elizabeth Petit Kneller, Genomics/ Diabetes Research Center  
        "The functional role of CDKAL1, a Diabetes susceptibility gene"  

 24- Victor Ortega, Genomics/ Pulmonary
        "Rare genetic vatiation and epigenomics of the beta2-adrenergic receptor gene"

March   

 3- Yun Li, UNC- Biostat and Genetics 
        "Imputation and next-generation imputation"  

 8- Mark Neff, TGEN/ Van Andel Research Institute
        "Dog Genetics: A fetching model organism"  

 10- Yan Wang, Harvard Medical School
        "Effects of dietary supplements on NASH-promoted early hepatocarcinogenesis in a rat model"  

 17- Carol Shively, Comparative Medicine
        "Monkey models of social stress-related disease: Vignettes on obesity, depression, and CVD"  

 24- Chad Haldeman-Englert, Pediatrics/ Medical Genetics
        "Utilization of DNA microarrays in the clinical setting"

April   

 7- Jielin Sun, Center for Cancer Genomics
        "Prediction of Prostate Cancer risk using SNPs"  

 14- Bingzhong Xue, Genomics/ Diabetes Research Center
        "Epigenetic regulation of macrophage polarization in obesity, inflammation, and insulin resistance"  

 September 

1- David Herrington, MD, Cardiology/ Genomics and Personalized Medicine Research
        "The Search for Genetic Determinants of Premature Atherosclerosis"

8- Jianfeng Xu, PhD, Center for Cancer Genomics
        "Recent Progress of Genetic Studies of Prostate Cacner and their Clinical Utility"

15- Satoru Hayasaka, PhD, PHS Biostatistics
        "A Network of Genes, Genetic Disorders, and Brain Areas"

22- Mark Hall, JD, PHS SSHP/ WFU School of Law
        "Genetic Discrimination:  Fear versus Reality"

29- Paula Ramos, PhD, PHS Biostatistics
        "Meta-Analysis of Autoimmune Variants Shared Between Systemic Lupus Erythematosus (SLE) and 16 Other Diseases Identifies Novel SLE loci"

 October 

6- Jill Ohar, MD, Pulmonary/ Genomics and Personalized Medicine Research
         "Genetics and COPD"

13- Fred Perrino, PhD, Biochemistry
        "Managing DNA and RNA to Prevent Autoimmune Disease"

20- Tim Howard, PhD, Pedicatrics/ Genomics and Personalzied Medicine Research
         "A Survey of Web-based Resources for Genomic Analysis"

27- Gregory Hawkins, PhD, Genomics and Personalized Medicine Research
         "Effects of IL6/IL6R on Lung Function in Asthmatics"

 November 

10- Emmanuel Opara, PhD, Wake Forest Institute for Regenerative Medicine
        "Bioengineering a Bioartificial Pancreas"

17- Swapan Das, PhD MS, Endocrinology/ Internal Medicine
        "Understanding Early Pathophysiology of Type 2 Diabetes in Humans by Integrating Physiological, Cell Biological, Gene Expression and Genetic Association Studies"

 December 

1- Xingnan Li, PhD MS, Genomics and Personalized Medicine Research
        "GWAS of Asthma and Asthma-Related traits... Common Variants Multiple Diseases"

8- Wennuan Liu, PhD, Center for Cancer Genomics
        "Somatic DNA Copy Number Alterations and Their Utility for Prognosis in Prostate Cancer"

15- Donald Bowden, PhD, Center for Diabetes Research
        "Rare Genetic Variants in Adiponectin:  Genetic and Metabolic Surprises"

 January 2011 

5- Barry Freedman, MD, Nephrology
        "Genetic Dissection of complex Kidney Disease: APOL1 and Non-Diabetic Nephropathy"

12- Steve Kritchevsky, PhD, Sticht Center
        "Genotypes and Phenotypes in Aging Research"

19- Stephen Peters, MD, PhD, Pulmonary/ Genomics and Personalized Medicine Research
        "Tiotropium Bromide Step Up Therapy for Adults with Uncontrolled Asthma:  Toward Individual Patient Responder Analysis in Clinical Trials"

26-  Dana Albon, MD, MS, Pulmonary Fellow
        "Obesity Asthma Interaction"

 February 

2- Sujoy Ghosh, PhD, NC Central University
        "Understanding Obesity Through Gene Expression Profiling in Skeletal Muscle and Whole Blood"

9- Annette Hastie, PhD, Pulmonary/ Genomics and Personalized Medicine Research
        "Biomarker Responses to Steroid Intervention in Asthma"

16- Carl Langefeld, PhD, PHS Biostatistics

23- Megan Rudock, PhD, PHS Epidemiology
        "Genetic Determinants of Visceral Adiposity in the Health Aging and Body Composition Study" 

 March 

2- Scott Cramer, PhD, Cancer Biology/ Center for Cancer Genomics
        "Tak1 and Prostate Cancer"

9- Rodolfo Pascual, MD, Pulmonary/ Genomics and Personalized Medicine Research
        "Vitamin D Deficiency and Asthma"

16- Bingzhong Xue, PhD, Center for Diabetes Research
        "The Nutrient Sensors AMPK and SIRT1 Link Inflammation to Insulin Sensititivity"

23- Jasmin Divers, PhD, PHS Biostatistics
         "Admixture Mapping Efforts in the African-American Diabetes Heart Study (AA-DHS)"

30- Denise Houston, PhD, Internal Medicine/ Gerontology
        "Vitamin D, vitamin D-related Genes and Health Outcomes"

 April 

6- Mac Robinson, PhD, Genomics and Personalized Medicine Research
        "Functional Changes Induced by IL-6 Trans-Signaling in Airway Smooth Muscle"

13- Tina Brinkley, PhD, Internal Medicine/ Gerontology

20- Richard Loeser, MD, Molecular Medicine
        "Discovery of New Pathways Contributing to Osteoarthritis Using Gene Expression Microarrays and Network Analysis"

27- Fang-Chi Hsu, PhD, PHS Biostatistics/ Center for Cancer Genomics  
        "Risk Prediction for Prostate Cancer"