Cynthia J. Lees, DVM, PhD
Assistant Professor of Pathology (Comparative Medicine)
Currently, I am examining novel compounds (SERMS, soy protein, PTH) to see if they prevent osteoporosis in the cynomolgus monkey model. This monkey model provides valuable information about cortical bone changes which can not be detected in the rat, the other major model used in osteoporosis research. Bone biomarkers, bone densitometry and bone histomorphometry are used to monitor drug induced changes during these experiments. Other areas of interest include trying to maximize peak bone mass during adolescence to prevent osteoporosis at menopause and examining skeletal changes due to pregnancy and lactation.