Kylie Kavanagh, DVM MS MPH
Associate Professor of Pathology (Comparative Medicine)
My interests lie in understanding how aging changes the body's physiology and ability to cope with metabolic stress, eventually resulting in pre-diabetes or diabetes. Higher glucose not only increases the oxidative load on all cells but also impairs the ability to respond and cope with that insult. I am particularly interested in the chaperone proteins (heat shock protein family) and their loss of inducibility with age and diabetes, and how this facilitates multisystemic health declines. We are also actively researching nutritional influences on obesity and glucose metabolism, looking particularly at the effects of different fat, simple carbohydrate and protein sources. We evaluate the microbiome and intestinal function under nutritional stress at different life-stages.