Kylie Kavanagh, DVM MS MPH

Assistant Professor of Pathology (Comparative Medicine)

Tel: 336-716-1555
Fax: 336-716-1515
kkavanag@wakehealth.edu

Current Research:

My interests lie in understanding how a chronic hyperglycaemic state changes the body's ability to cope with metabolic stress. High glucose not only increases the oxidative load on all cells but also impairs the ability to respond and cope with that insult. I am particularly interested in the chaperone proteins (heat shock protein family) and their loss of inducibility with diabetes, the changes in extracellular matrix and antioxidant super oxide dismutases which can lead to further cell damage which can manifest as endothelial dysfunction and eventual atherogenesis. We are also actively researching nutritional influences on obesity and carbohydrate metabolism, looking particularly at the effects of different fat and protein sources and hope to expand these findings into evaluating pre- and post-natal effects of maternal nutrition.

Publications:

Quick Reference

Section Head:
Jay Kaplan, PhD

Tel: 336-716-1500
Fax: 336-716-1515

Department of Pathology
Comparative Medicine
WF School of Medicine
Medical Center Boulevard
Winston-Salem, NC 27157
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Last Updated: 02-04-2014
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