Biostatistics and Bioinformatics Shared Resource

Scott Isom, M.S.

Biostatistician III
Department of Biostatistical Sciences 
Division of Public Health Sciences
Wake Forest University School of Medicine
Medical Center Blvd. 
Winston-Salem, NC 27157
Tel: (336) 716-0758 or (336) 716-9004
Fax: (336)716-6427
Email: sisom@wakehealth.edu

Education

University of Nebraska - Lincoln - MS, Statistics
Chadron State College - BS, Education

Research Topics

  • Cancer research
  • Cancer prevention
  • Diabetes prevention

Current Research

Scott Isom, MS, is a Biostatistician III and has been a member of the CCCWFU Biostatistics core since October 2006 in the Department of Biostatistical Sciences.  He works with basic science, clinical, and cancer control researchers to design new studies, analyze data, and assist with manuscript development. As part of the Operation Protocol Service (OPS), he has a large role in the review of cancer research protocols. In addition to providing support for the Cancer Center Biostatistics Core, Scott is also involved in a number of social science studies. 

Selected Publications

  1. Jones E, Isom S, Kemper KJ, McLean TW.  Acupressure for chemotherapy-associated nausea and vomiting in children.  J Soc Integr Oncol. 2008 Fall;6(4):141-5.
  2. Muhammad FS, Goode AK, Kock ND, Arifin EA, Cline JM, Adams MR, Hoyer PB, Christian PJ, Isom S, Kaplan JR, Appt SE.  Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes.  Comp Med. 2009 Feb;59(1):46-59.  PMCID: PMC2703138.  
  3. Monjazeb AM, Riedlinger G, Aklilu M, Geisinger KR, Mishra G, Isom S, Clark P, Levine EA, Blackstock AW Outcomes of patients with esophageal cancer staged with [¹⁸F]fluorodeoxyglucose positron emission tomography (FDG-PET): can postchemoradiotherapy FDG-PET predict the utility of resection?.J Clin Oncol. 2010 Nov 1;28(31):4714-21. PMCID: PMC3020701
  4. Burger KL, Davis AL, Isom S, Mishra N, Seals DF. Cytoskeleton (Hoboken). The podosome marker protein Tks5 regulates macrophage invasive behavior. 2011 Dec;68(12):694-711.  Epub 2011 Nov 8. PMCID: PMC3240724.
  5. Munley MT, Moore JE, Walb MC, Isom SP, Olson JD, Zora JG, Kock ND, Wheeler KT, Miller MS.  Cancer-prone mice expressing the Ki-rasG12C gene show increased lung carcinogenesis after CT screening exposures.  Radiat Res. 2011 Dec;176(6):842-8. PMCID: PMC3244170. 
  6. Pomper GJ, Wilson E, Isom S, Hurd DD A validation study of new cryopreservation bags for implementation in a blood and marrow transplant laboratory.  Transfusion. 2011 Jun;51(6):1291-5. PMCID: PMC3833727
  7. Tawfik B, Sliesoraitis S, Lyerly S, Klepin HD, Lawrence J, Isom S, Ellis LR, Manuel M, Dralle S, Berenzon D, Powell BL, Pardee T. Efficacy of the hypomethylating agents as frontline, salvage, or consolidation therapy in adults with acute myeloid leukemia (AML). Ann Hematol. 2014 Jan;93(1):47-55. doi: 10.1007/s00277-013-1940-9. PMCID: PMC3879720.
  8. Burger KL, Learman BS, Boucherle AK, Sirintrapun SJ, Isom S, Díaz B, Courtneidge SA, Seals DF. Src-dependent Tks5 phosphorylation regulates invadopodia-associated invasion in prostate cancer cells. Prostate. 2014 Feb;74(2):134-48. doi: 10.1002/pros.22735. PMCID: PMC4083496.
  9. Lucas JT Jr, Nida AM, Isom S, Marshall K, Bourland JD, Laxton AW, Tatter SB, Chan MD. Predictive nomogram for the durability of pain relief from gamma knife radiation surgery in the treatment of trigeminal neuralgia. Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):120-6. doi: 10.1016/j.ijrobp.2014.01.023. PMCID: PMC4127576.
  10. Pardee TS, Lee K, Luddy J, Maturo C, Rodriguez RJ, Isom S, Miller LD, Stadelman KM, Levitan D, Hurd D, Ellis LR, Harrelson R, Manuel M, Dralle S, Lyerly S, Powell BL. A Phase I Study of the First-in-Class Anti-Mitochondrial Metabolism Agent, CPI-613, in Patients with Advanced Hematologic Malignancies. Clin Cancer Res. 2014 Aug 27. pii: clincanres.1019.2014. PMCID: PMC4199870.
  11. Ayala-Peacock DN, Peiffer AM, Lucas JT, Isom S, Kuremsky JG, Urbanic JJ, Bourland JD, Laxton AW, Tatter SB, Shaw EG, Chan MD. A nomogram for predicting distant brain failure in patients treated with gamma knife stereotactic radiosurgery without whole brain radiotherapy.  Neuro Oncol. 2014 Sep;16(9):1283-8. doi: 10.1093/neuonc/nou018. Epub 2014 Feb 20. PMCID: PMC4136890.

Quick Reference

Biostatistics and Bioinformatics Shared Resource
Executive Director
Ralph D'Agostino Jr., PhD

336-716-9410
336-716-9011

rdagosti@wakehealth.edu

Co-Director
Xiaobo Zhou, PhD

xizhou@wakehealth.edu

Senior Biostatisticians
Janet Tooze, PhD

jtooze@wakehealth.edu

Doug Case, PhD

dcase@wakehealth.edu

Fang-Chi Hsu, PhD

fhsu@wakehealth.edu

Senior Bioinformaticians
Carl Langefeld, PhD

clangefe@wakehealth.edu

Guangxu Jin, PhD

gjin@wakehealth.edu

Jing Su, PhD

jsu@wakehealth.edu

Biostatisticians
Scott Isom, MS

sisom@wakehealth.edu

Greg Russell, MS

grussell@wakehealth.edu

Beverly Levine, PhD

blevine@wakehealth.edu

Bioinformaticians
Jeff Chou, PhD

jchou@wakehealth.edu

Liang Lui, PhD

lliu@wakehealth.edu

Dave McWilliams, PhD

dmcwilli@wakehealth.edu

Jian Zhang, PhD

jizhang@wakehealth.edu

Administrator
Tina Martin, BSBA

timartin@wakehealth.edu

 

    Find A Doctor Ways to Give
    Last Updated: 03-23-2016
    Magnet Hospital RecognitionConsumer Choice2015 Best DoctorsJoint Commission Report

    Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.