Biostatistics and Bioinformatics Shared Resource

Published Research

Citation Reference Language for Use of Shared Resource

Example citation: “The Biostatistics and Bioinformatics Shared Resource services are supported by the Comprehensive Cancer Center of Wake Forest Baptist Medical Center, NCI CCSG P30CA012197 grant.”


Program Key: CPC = Cancer Prevention and Control Program; CRP = Clinical Research Program; TPR = Tumor Progression and Recurrence Program; CBB = Cancer Biology and Biochemistry Program

  1. Gralnek IM, Siersema PD, Halpern Z, Segol O, Melhem A, Suissa A, Santo E, Sloyer A, Fenster J, D'Agostino RB Jr.(CPC), Dik VK, et al.. Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial. Lancet Oncol. 2014;15: 353-60. PMC4062184.
  2. Rapp SR(CRP), Case LD(CRP), Peiffer A, Naughton MM, Chan MD(CRP), Stieber VW, Moore DF, Jr., Falchuk SC, Piephoff JV, Edenfield WJ, Shaw EG(CPC), et al.. Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial. J Clin Oncol. 2015;33(15): 1653-9. PMC4429174.
  3. Vitolins MZ(CPC), Griffin L, Tomlinson WV, Vuky J, Adams PT, Moose D, Frizzell B, Lesser GJ(CRP), Naughton M(CPC), Radford JE, Jr., Shaw EG(CPC). Randomized Trial to Assess the Impact of Venlafaxine and Soy Protein on Hot Flashes and Quality of Life in Men With Prostate Cancer. J Clin Oncol. 2013;31(32): 4092-8. PMC3816959.
  4. Hassan S, Karpova Y, Baiz D, Yancey D, Pullikuth A, Flores A, Register T, Cline JM(TPR), D'Agostino R, Jr.(CPC), Danial N, Kulik G(TPR), et al.. Behavioral stress accelerates prostate cancer development in mice. J Clin Invest. 2013;123(2): 874-86. PMC3561807.
  5. Sun J(CPC), Na R, Hsu FC, Zheng SL(CPC), Wiklund F, Condreay LD, Trent JM, Xu J(CPC). Genetic score is an objective and better measurement of inherited risk of prostate cancer than family history. Eur Urol. 2013;63(3): 585-7. PMC3730447.
  6. Kader AK, Sun J(CPC), Reck BH, Newcombe PJ, Kim ST, Hsu FC, D'Agostino RB, Jr.(CPC), Torti FM(CBB), Zhang Z, Zheng SL(CPC), Xu J(CPC), et al.. Potential Impact of Adding Genetic Markers to Clinical Parameters in Predicting Prostate Biopsy Outcomes in Men Following an Initial Negative Biopsy: Findings from the REDUCE Trial. Eur Urol. 2012;62(6): 953-61. PMC3568765.
  7. Nagalla S, Chou JW, Willingham MC, Ruiz J(CRP), Vaughn JP, Dubey P(TPR), Lash TL(CPC), Hamilton-Dutoit, Bergh J, Sotiriou C, Miller LD(TPR), et al.. Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis. Genome Biol. 2013;14(4): R34. PMC3798758.
  8. Castellino SM(CRP), Geiger AM(CPC), Mertens AC, Leisenring WM, Tooze JA(CPC), Goodman P, Stovall M, Robison LL, Hudson MM. Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. Blood. 2011;117(6): 1806-1816. PMC3056636.
  9. Klepin HD(CRP), Geiger AM(CPC), Tooze JA(CPC), Kritchevsky SB, Williamson JD, Pardee TS(CRP), Ellis LR, Powell BL(CRP). Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Blood. 2013;121(21): 4287-94. PMC3663423.
  10. Wang W, Deng Z, Hatcher H, Miller LD(TPR), Di X, Tesfay L, Sui G(TPR), D'Agostino RB(CPC), Torti FM, Torti SV. IRP2 Regulates Breast Tumor Growth. Cancer Res. 2014;74(2): 497-507. PMC3989290.
  11. Liu L, Jin G, Zhou X(TPR). Modeling the relationship of epigenetic modifications to transcription factor binding. Nucleic Acids Res. 2015;43(8): 3873-85. PMC4417166.
  12. Suresh V, Liu L, Adjeroh D, Zhou X(TPR). RPI-Pred: predicting ncRNA-protein interaction using sequence and structural information. Nucleic Acids Res. 2015;43(3): 1370-9. PMC4330382.
  13. Pardee TS(CRP), Lee K, Luddy J, Maturo C, Rodriguez RJ, Isom S, Miller LD(TPR), Ellis LR, Levitan D, Hurd D(CRP), Powell BL(CRP), et al.. A Phase I Study of the First-in-Class Anti-Mitochondrial Metabolism Agent, CPI-613, in Patients with Advanced Hematologic Malignancies. Clin Cancer Res. 2014;20(20): 5255-64. PMC4199870.
  14. Peiffer AM(CRP), Leyrer CM, Greene-Schloesser DM, Shing E, Kearns WT, Shaw EG(CPC), Tatter SB, Ip EH, Rapp SR(CRP), Robbins ME(CBB), Chan MD(CRP), et al.. Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline. Neurology. 2013;80(8): 747-53. PMC3589296.
  15. Sastry KS, Al-Muftah MA, Li P, Al-Kowari MK, Wang E, Ismail Chouchane A, Kizhakayil D, Kulik G(TPR), Marincola FM, Haoudi A, Chouchane L. Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells. Cell Death Differ. 2014;21(12): 1936-49. PMC4227153.
  16. Rajani KR, Pettit Kneller EL, McKenzie MO, Horita DA(CBB), Chou JW, Lyles DS(TPR). Complexes of vesicular stomatitis virus matrix protein with host rae1 and nup98 involved in inhibition of host transcription. PLoS Pathog. 2012;8(9): e1002929. PMC3460625.
  17. Miller LD(TPR), Coffman LG, Chou JW, Black MA, Bergh J, D'Agostino R, Jr.(CPC), Torti SV(CBB), Torti FM(CBB). An Iron Regulatory Gene Signature Predicts Outcome in Breast Cancer. Cancer Res. 2011;71(21): 6728-6737. PMC3206152.
  18. Burke AR, Singh RN(CBB), Carroll DL(CRP), Wood JCS, D'Agostino RB(CPC), Ajayan PM, Torti FM(CBB), Torti SV(CBB). The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy. Biomaterials. 2012;33(10): 2961-2970. PMC3286596.
  19. Burke AR, Singh RN, Carroll DL(CRP), Owen JD, Kock ND, D'Agostino R(CPC), Torti FM(CBB), Torti SV(CBB). Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials. 2011;32(26): 5970-5978. PMC3130101.
  20. Kongbundansuk S, Hundley WG(CPC). Noninvasive Imaging of Cardiovascular Injury Related to the Treatment of Cancer. JACC Cardiovasc Imaging. 2014;7(8): 824-838. PMC4183055.


Quick Reference

Biostatistics and Bioinformatics Shared Resource
Executive Director
Ralph D'Agostino Jr., PhD


Xiaobo Zhou, PhD

Senior Biostatisticians
Janet Tooze, PhD

Doug Case, PhD

Fang-Chi Hsu, PhD

Senior Bioinformaticians
Carl Langefeld, PhD

Guangxu Jin, PhD

Jing Su, PhD

Scott Isom, MS

Greg Russell, MS

Beverly Levine, PhD

Jeff Chou, PhD

Liang Lui, PhD

Dave McWilliams, PhD

Jian Zhang, PhD

Tina Martin, BSBA


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