James F. Lovato, MS

Lovato_image007 James F. Lovato, MS
Biostatistician IV
Department of Biostatistical Sciences
Section on Biostatistics
Wake Forest University School of Medicine
Medical Center Boulevard
Winston-Salem, NC 27157
Tel: 336-713–4172 or 336-716–9004
Fax: 336-716-5425


University of Washington – MS, Biostatistics
Rice University – BS, Mathematical Science

Research Topics:

Cancer treatment
Group sequential trial design and analysis
Survival analysis
Cognitive and microvascular effects of diabetes and treatment
Dynamic visual display of data

Current Research:

James Lovato is a Biostatistician IV and has been a member of the CCCWFU Biostatistics core since 2000.  He currently works with clinical, cancer control, and basic science researchers in designing new studies, providing assistance in the development of protocols and grants, analyzing data, and assisting with manuscript development. He has extensive experience writing statistical sections for treatment protocols, including plans for interim monitoring of trial results. James actively provides methodologic support to CCCWFU investigators, performs interim and final data analyses, and collaborates in interpreting and publishing results.

Selected Recent Publications:

Center B, Petty WJ, Ayala D, Hinson WH, Lovato J, Capellari J, Oaks T, Miller AA, Blackstock AW. A  phase I study of getitinib with concurrent dose-escalted weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage III non-small cell lung cancer. J Thorac Onoc. 2010 Jan;5(1):69-754.

Saconn PA, Shaw EG, Chan MD, Squire SE, Johnson AJ, McMullen KP, Tatter SB, Ellis TL, Lovato J, Bourland JD, Ekstrand KE, DeGuzman AF, Munley MT. Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: a single-institution retrospective review. Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1142-6.

Aubuchon AC, Chan MD, Lovato JF, Balamucki CJ, Ellis TL, Tatter SB, McMullen KP, Munley MT, Deguzman AF, Ekstrand KE, Bourland JD, Shaw EG. Repeat Gamma Knife Radiosurgery for Trigeminal Neuralgia. Int J Radiat Oncol Biol Phys. 2010 Oct 5.

Barber A, Lovato J, Hill G, McLean TW. Measurement of cerebrospinal fluid protein is unnecessary in children with leukemia. Pediatr Blood Cancer. 2008 May 2.

Kemper KJ, Hamilton CA, McLean TW, Lovato J. Impact of music on pediatric oncology outpatients. Pediatr Res. 2008 Jul;64(1):105-9.

Stieber V, Robbins M, Balamucki C, deGuzman A, Tatter S, Ekstrand K, McMullen K, Branch C, Shaw E, Bourland JD, Lovato J, Munley M, Ellis T. Determination of a clinical value for the repair half-time (T1/2) of the trigeminal nerve based on outcome data from gamma knife radiosurgery for facial pain. Radiat Res. 2007 Aug;168(2):143-8.

Petty WJ, Knight SN, Mosley L, Lovato J, Capellari J, Tucker R, Blackstock AW, Miller MS, Miller AA. A pharmacogenomic study of docetaxel and gemcitabine for the initial treatment of advanced non-small cell lung cancer. J Thorac Oncol. 2007 Mar;2(3):197-202.

Danhauer SC, Rutherford CA, Hurt G, Gentry S, Lovato J, McQuellon RP. Providing psychosocial group support for young women with breast cancer: findings from a wellness-based community collaboration. J Psychosoc Oncol. 2007;25(1):103-20.

Molnár I, Stark N, Lovato J, Powell BL, Cruz J, Hurd DD, Mathieu JS, Chen TC, Holick MF, Cambra S, McQuellon RP, Schwartz GG. Treatment of low-risk myelodysplastic syndromes with high-dose daily oral cholecalciferol (2000-4000 IU vitamin D(3)). Leukemia. 2007 May;21(5):1089-92. Epub 2007 Mar 8.

Danhauer SC, Marler B, Rutherford CA, Lovato JF, Asbury DY, McQuellon RP, Miller BE.  Music or guided imagery for women undergoing colposcopy: a randomized controlled study of effects on anxiety, perceived pain, and patient satisfaction. J Low Genit Tract Dis. 2007 Jan;11(1):39-45.

Balamucki CJ, Stieber VW, Ellis TL, Tatter SB, Deguzman AF, McMullen KP, Lovato J, Shaw EG, Ekstrand KE, Bourland JD, Munley MT, Robbins M, Branch C. Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobalt. J Neurosurg. 2006 Nov;105(5):730-5.

Blackstock AW, Aklilu M, Lovato J, Farmer MR, Mishra G, Melin SA, Oaks T, Geisinger K, Levine EA. Pathologic complete response may not represent the optimal surrogate for survival after preoperative therapy for esophageal cancer. Int J Gastrointest Cancer. 2006;37(1):7-14.

Borden LS Jr, Clark PE, Lovato J, Hall MC, Stindt D, Harmon M, M Mohler R, Torti FM. Vinorelbine, doxorubicin, and prednisone in androgen-independent prostate cancer. Cancer. 2006 Sep 1;107(5):1093-100.

Clark PE, Hall MC, Borden LS Jr, Miller AA, Hu JJ, Lee WR, Stindt D, D'Agostino R Jr, Lovato J, Harmon M, Torti FM. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse of prostate cancer after definitive local therapy.Urology. 2006 Jun;67(6):1257-61.

Hawfield A, Lovato J, Covington D, Kimmick G. “Retrospective study of the effect of comorbidity on use of adjuvant chemotherapy in older women with breast cancer in a tertiary care setting.” Crit Rev Oncol Hematol. 2006 Sep;59(3):250-5. Epub 2006 Mar 9.

Levine EA, Farmer MR, Clark PB, Mishra G, Ho C, Geisinger KR, Melin SA, Lovato J, Oaks T, Blackstock AW. Predictive value of 18-fluoro-deoxy-glucose-positron emission tomography (18FDG-PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer. Annuals of Surgery. 2006 Apr;243(4):472-8.

Edward G. Shaw, Robin Rosdhal, Ralph B. D’Agostino Jr, James Lovato, Michelle J. Naughton, Michael E. Robbins, and Stephen R. Rapp. Phase II Study of Donepezil in Irradiated Brain Tumor Patients: Effect on Cognitive Function, Mood, and Quality of Life. Journal of Clinical Oncology. Mar 20:24(9):1415-20.

Kimmick, G., Lovato, J., McQuellon, J., Robinson, E.,  Muss, H. Randomized, Placebo-Controlled Study of Sertraline (Zolofttm) for the Treatment of Hot Flashes in Women With Early Stage Breast Cancer Taking Tamoxifen. Breast Journal. 2006 Mar-Apr;12(2):114-22.

Peter E. Clark, M. Craig Hall, Lester S. Borden, Jr., Antonius A. Miller, Jennifer J. Hu, W. Robert Lee, Michelle Harmon, Ralph D’Agostino Jr., James Lovato, Diana Stindt, Frank M. Torti. A Phase I/II Prospective Dose Escalating Trial of Lycopene in Patients with Biochemical Relapse of Prostate Cancer following Definitive Local Therapy. Urology. 2006 Jun;67(6):1257-61.

Schwartz GG, Hall MC, Stindt D, Patton SE, Lovato JF, Torti FM. Phase I/II Study of 19-nor-1-25-Dihydroxyvitamin D2 (Paricalcitol) in Advanced, Androgen Insensitive Prostate Cancer. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8680-5.

Hill G, Chauvenet AR, Lovato J, McLean TW. Recent steriod therapy increases severity of varicell infections in children with acute lymphoblastic leukemia. Pediatrics. 2005 Oct;116(4):e525-9.

Blackstock AW, Farmer MR, Lovato J, Mishra G, Melin SA, Oaks T, Aklilu M, Clark PB, Levine EA. A prospective evaluation of the impact of 18-F-fluoro-deoxy-D-glucose positron emission tomography staging on survival for patients with locally advanced esophageal cancer. Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):455-60. Epub 2005 Oct 5.

Kleinpeter KP, Lovato J, Clark PB, Wooldridge T, Norman ES, Bergman S, Perrier ND. Is parathyroid carcinoma indeed a lethal disease? Annals of Surgical Oncology, 2005; 12(3): 1-7.

Clark P, Wooldridge T, Kleinpeter K, Perrier N, Lovato J, Morton K. Providing optimal preoperative localization for recurrent parathroid carcinoma: a combined parathyroid scintigraphy and computed tomography approach. Clinical Nuclear Medicine. 2004 Nov; 29 (11): 681-4.

Last Updated: 10-28-2014
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