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Cancer Genomics Shared Resource

Services We Provide

Tools and Instrumentation Used

    The CGSR has a modern infrastructure that includes:

    • Illumina NextSeq 500 NGS
    • Illumina MiSeq NGS
    • Affymetrix GeneAtlas Microarray System
    • Agilent 2100 Bioanalyzer
    • Custom scripts for data processing (R coding)

    Typical Experiments and Expertise

    Next Generation Sequencing (NGS)

    • RNAseq – gene expression profiling, gene fusion analysis, allele specific expression, splice variant detection, microRNA (miRNA) detection, long non-coding RNA (lncRNA) detection
    • Exome Sequencing – identification and validation of genetic variants (mutations, SNPs, insertion-deletions (InDels)
    • Whole genome sequencing – mutation detection, tumor profiling, denovo genome sequencing
    • Methylation sequencing – whole genome bisulfite sequencing, methylation enrichment (methylation binding protein)
    • ChIPseq – transcription factor binding site identification


    • Expression profiling – mRNA/miRNA/lncRNA profiling, tumor profiling, time course assays
    • Copy number variation (CNV) detection – tumor profiling, genetic association
    • SNP analysis – genome-wide association analysis
    • ChIP-chip – transcription factor binding site identification


    • Data processing and quality control
    • Data normalization
    • Differential expression analysis
    • Mutational analysis
    • Clinico-genomic correlation analysis
    • Data visualization
    • Pathway enrichment analysis
    • Data mining and custom informatics

      How to Schedule Services

      See Sample Submission.


      Quick Reference

      Cancer Genomics Shared Resource
      Lance D. Miller, PhD


      Gregory Hawkins, PhD


      Technical Staff
      Lou Craddock


      Wei Cui


      Jamie Haywood


      Dr. Jeff Chou


      Hanes 4026/4028
      NRC 311/312
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